Hiroshi Tamura
Kyoto University
OphthalmologyPhysicsInternal medicineSurgeryCardiologyElectrodeInorganic chemistryChemistryPolymer chemistryMaterials scienceMacular degenerationVisual acuityChitosanPercutaneous coronary interventionChitinComputer scienceChemical engineeringTissue engineeringMedicineBiology
789Publications
86H-index
20.3kCitations
Publications 563
Newest
#1Yuichiro Shirafuta (Yamaguchi University)H-Index: 5
#2Isao Tamura (Yamaguchi University)H-Index: 20
Last. Shun Sato (Yamaguchi University)H-Index: 19
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The ovulatory luteinizing hormone (LH) surge induces rapid changes of gene expression and cellular functions in granulosa cells (GCs) undergoing luteinization. However, it remains unclear how the changes in genome-wide gene expression are regulated. H3K4me3 histone modifications are involved in the rapid alteration of gene expression. In this study, we investigated genome-wide changes of transcriptome and H3K4me3 status in mouse GCs undergoing luteinization. GCs were obtained from mice treated w...
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Abstract null Purpose null To report fundamental epidemiological data for choroidal parameters such as choroidal thickness and index of choroidal vascularity in Japanese individuals, and to evaluate their correlations with age, sex, systemic parameters, and other ocular parameters. null Design null Population-based cohort study. null Participants null A total of 9,850 individuals participated in the first follow-up of the Nagahama Prospective Cohort for Comprehensive Human Bioscience (the Nagaha...
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#1Takahashi N (CIT: Center for Information Technology)
#2Saeki S (Ehime University)
Last. Akitaka Tsujikawa (Kyoto University)H-Index: 60
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We developed a novel scotoma detection system using time required for fixation to the random targets, or the "eye-guided scotoma detection method". In order to verify the "eye-guided scotoma detection method", we measured 78 eyes of 40 subjects, and examined the measurement results in comparison with the results of measurement by Humphrey perimetry. The results were as follows: (1) Mariotte scotomas were detected in 100% of the eyes tested; (2) The false-negative rate (the percentage of cases wh...
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#1Isao Tamura (Yamaguchi University)H-Index: 20
#2Hiroshi Tamura (Yamaguchi University)H-Index: 39
Last. Shun Sato (Yamaguchi University)H-Index: 19
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Women usually experience body weight gain with aging, which can put them at risk for many chronic diseases. Previous studies indicated that melatonin treatment attenuates body weight gain and abdominal fat deposition in several male animals. However, it is unclear whether melatonin affects female animals in the same way. This study investigated whether long-term melatonin treatment can attenuate body weight gain with aging and, if it does, what the mechanism is. Ten-week-old female ICR mice were...
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#1Hiroshi TamuraH-Index: 86
#1Hiroshi TamuraH-Index: 39
Last. Isao NagaokaH-Index: 56
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The blue blood of the horseshoe crab is a natural, irreplaceable, and precious resource that is highly valued by the biomedical industry. The Limulus amebocyte lysate (LAL) obtained from horseshoe crab blood cells functions as a surprisingly sophisticated sensing system that allows for the extremely sensitive detection of bacterial and fungal cell-wall components. Notably, LAL tests have markedly contributed to the quality control of pharmaceutical drugs and medical devices as successful alterna...
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#1Sufian Elfandi (Kyoto University)H-Index: 1
#2Sotaro Ooto (Kyoto University)H-Index: 46
Last. Akitaka Tsujikawa (Kyoto University)H-Index: 60
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Purpose To compare the 12-month efficacy of intravitreous aflibercept (IVA) injection between eyes with pachychoroid neovasculopathy and neovascular age-related macular degeneration (AMD). Methods Retrospective, comparative case series analysis. Twenty-seven eyes with pachychoroid neovasculopathy and sixty-three eyes with neovascular AMD. All patients received three initial monthly, followed by bimonthly, IVA injections. Results Twelve months after initial treatment, the mean best-corrected visu...
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#1Ayaka Doi (Kyoto University)
#2Manabu Miyata (Kyoto University)H-Index: 13
Last. Akitaka Tsujikawa (Kyoto University)H-Index: 60
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PURPOSE To investigate long-term visual outcome in inferior posterior staphyloma (IPS) in each group classified based on macular complications and to examine the treatment effect for eyes with IPS with choroidal neovascularization (CNV) DESIGN: Prospective clinical cohort study PARTICIPANTS: We analyzed 56 eyes of 43 consecutive patients with IPS who were followed for 4 years. METHODS We classified eligible eyes into three groups based on baseline findings: eyes without CNV or retinal exudate (n...
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Gender equality is one of the most important issues in the promotion of diversity. The participation status of female urologists in academic activities has not been clarified. In the present study, we analyzed a total of 10,288 articles published by 58,914 authors in Acta Urologica Japonica since the first issue in 1955 to the present. The author's gender was determined by an application program interface for gender estimation in combination with independent manual confirmation by two researcher...
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#1Atsuro Sawada (Kyoto University)H-Index: 4
#2Shusuke Hiragi (Kyoto University)H-Index: 5
Last. Osamu Ogawa (Kyoto University)H-Index: 79
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Abstract Background Renal transplantation improves the quality of life (QOL) of end-stage renal disease (ESRD) patients with renal failure. However, it remains unclear which renal disease-specific QOL aspects determine general health-related QOL of ESRD patients. This study aimed to identify these QOL items by examining the QOL of ESRD patients using the Kidney Disease Quality of Life-Short Form (KDQOL-SF), version 1.3, and EuroQoL-5 dimension-5 levels (EQ-5D-5L) questionnaires. Methods We condu...
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#1Kentaro Fukuda (Juntendo University)H-Index: 3
#2Shinya Okazaki (Juntendo University)H-Index: 19
Last. Tohru Minamino (Juntendo University)H-Index: 62
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BACKGROUND A common complication of endovascular treatment for femoropopliteal lesions is bleeding at the vascular access site. Although risk factors of bleeding-associated complications at the approach site have been reported, the results have been inconclusive. Hence, this study aimed to assess the predictors of bleeding-associated complications at the approach site in patients undergoing endovascular treatment for femoropopliteal lesions. METHODS This retrospective, single-center, observation...
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