Weijuan Han
Guangzhou University of Chinese Medicine
DNA damageChemistryFree radical damage to DNACytosinePetroleum etherAmentoflavoneThymineDeoxyriboseKaempferolAntioxidantCaffeic acidGuanineRose (mathematics)Phenolic acidEthyl acetateFerulic acidABTSProtocatechuic acidQuercetinHylocereus undatusDPPHAtractylodes macrocephalaPlant scienceFood scienceReactive oxygen speciesDNABiochemistryTraditional medicineBotanyBiology
5Publications
4H-index
165Citations
Publications 5
Newest
Objective: Oxidative DNA damage is involved in mutation, cell death, carcinogenesis, and aging. Since biflavonoid amentoflavone exhibited beneficial effects on DNA, we therefore investigated its protection against •OH-induced DNA oxidative damage then discussed the mechanism. It will enhance the understanding of interaction between biflavonoid vs DNA mediated by free radicals. Methods: The protective effect of amentoflavone against •OH-induced DNA damage was measured using our method. To explore...
16 CitationsSource
#1Xican LiH-Index: 19
#1Xican LiH-Index: 1
Last. Dongfeng ChenH-Index: 1
view all 6 authors...
Objective: Oxidative DNA damage is involved in mutation, cell death, carcinogenesis, and aging. Since biflavonoid amentoflavone exhibited beneficial effects on DNA, we therefore investigated its protection againstOH-induced DNA oxidative damage then discussed the mechanism. It will enhance the understanding of interaction between biflavonoid vs DNA mediated by free radicals. Methods: The protective effect of amentoflavone againstOH-induced DNA damage was measured using our method. To explore the...
#1Xican LiH-Index: 19
#1Xican LiH-Index: 2
Last. Dongfeng ChenH-Index: 3
view all 6 authors...
4 CitationsSource
#1Xican Li (Guangzhou University of Chinese Medicine)H-Index: 19
#2Jing Lin (Guangzhou University of Chinese Medicine)H-Index: 4
Last. Dongfeng Chen (Guangzhou University of Chinese Medicine)H-Index: 3
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As a typical Chinese herbal medicine, rhizoma Cimicifugae (RC, 升麻 in Chinese) possesses various pharmacological effects involved in antioxidant activity. However, its antioxidant activity has not been reported so far. The aim of the present study was to systematically evaluate the antioxidant ability of RC in vitro, then discuss the mechanism. Firstly, five RC extracts (i.e. petroleum ether extract PERC, ethyl acetate extract EARC, absolute ethanol extract AERC, 95% ethanol extract 95ERC, and wa...
91 CitationsSource
#1Xican Li (Guangzhou University of Chinese Medicine)H-Index: 19
#2Jian LinH-Index: 7
Last. Dongfeng ChenH-Index: 22
view all 10 authors...
Rhizoma Atractylodes macrocephala (AM) has been used in Traditional Chinese Medicine (TCM) for about 2,000 years. In the study, we firstly determined the antioxidant levels of five AM extracts by •OH-scavenging, •O2−-scavenging, Fe2+-chelating, Cu2+-chelating, DPPH·-scavenging, and ABTS+·-scavenging assays. After measurement of the chemical contents in five AM extracts, we quantitatively analyzed the correlations between antioxidant levels and chemical contents. It was observed that total phenol...
58 CitationsSource