Simone P. Rauh
Public Health Research Institute
StatisticsEpidemiologyFramingham Risk ScoreRisk assessmentInternal medicineEndocrinologyExplained variationOddsSocioeconomic statusDemographyPsychologyRetrospective cohort studyPhysical exercisePhysical therapyProspective cohort studyEmergency medicineCohort studyHazard ratioObservational studyWaistType 2 diabetesPlasma membrane monoamine transporterDepression (differential diagnoses)DiseaseComorbidityInsulinConcomitantPrediabetesMetforminMetabolic syndromePopulationType 2 Diabetes MellitusConfidence intervalBootstrapping (statistics)Diabetes mellitusReceiver operating characteristicMedicineCohortGerontologyArea under the curveBlood pressureGastroenterology
Publications 29
#1Sytske van Bruggen (LEI: Leiden University)
#2Marise J. Kasteleyn (LEI: Leiden University)H-Index: 13
Last. Simone P. Rauh (VU: VU University Amsterdam)H-Index: 10
view all 6 authors...
BACKGROUND Structured primary diabetes care within a collectively supported setting is associated with better monitoring of biomedical and lifestyle-related target indicators among people with type 2 diabetes and with better HbA1c levels. Whether socioeconomic status affects delivery of care in terms of monitoring and its association with HbA1c levels within this approach, is unclear. This study aims to understand whether, within a structured care approach, 1) socioeconomic categories differ con...
#1Sytske van Bruggen (Loyola University Medical Center)
#2Marise J. Kasteleyn (LUMC: Leiden University Medical Center)H-Index: 13
Last. Niels H. Chavannes (LUMC: Leiden University Medical Center)H-Index: 51
view all 7 authors...
BACKGROUND Dutch standard diabetes care is generally protocol-driven. However, considering that general practices wish to tailor diabetes care to individual patients and encourage self-management, particularly in light of current COVID-19 related constraints, protocols and other barriers may hinder implementation. The impact of dispensing with protocol and implementation of self-management interventions on patient monitoring and experiences are not known. This study aims to evaluate tailoring of...
#7Marieke B. Snijder (PHRI: Public Health Research Institute)H-Index: 25
Background Most risk assessment models for type 2 diabetes (T2DM) have been developed in Caucasians and Asians; little is known about their performance in other ethnic groups. Objectives We aimed to identify existing models for the risk of prevalent or undiagnosed T2DM and externally validate them in a multi-ethnic population currently living in the Netherlands. Methods A literature search to identify risk assessment models for prevalent or undiagnosed T2DM was performed in PubMed until December...
#1Carolien Ruijgrok (PHRI: Public Health Research Institute)H-Index: 3
#2Ellen E. Blaak (UM: Maastricht University)H-Index: 79
Last. M.J. Alssema (PHRI: Public Health Research Institute)H-Index: 2
view all 9 authors...
Purpose: Reducing postprandial hyperglycemia has beneficial effects on diabetesrelated risk factors, but the magnitude of the reduction needed to achieve such an effect is unknown. To quantify the relationship of acute glucose and insulin postprandial responses with longer-term effects on diabetes-related risk factors by performing a systematic review and meta-analysis of dietary intervention studies. Methods: We systematically searched EMBASE and MEDLINE. Dietary intervention studies among any ...
#1Sytske van BruggenH-Index: 3
#2Simone P. Rauh (VU: VU University Amsterdam)H-Index: 10
Last. Marise J. Kasteleyn (LUMC: Leiden University Medical Center)H-Index: 13
view all 6 authors...
OBJECTIVE: Whether care group participation by general practitioners improves delivery of diabetes care is unknown. Using 'monitoring of biomedical and lifestyle target indicators as recommended by professional guidelines' as an operationalisation for quality of care, we explored whether (1) in new practices monitoring as recommended improved a year after initial care group participation (aim 1); (2) new practices and experienced practices differed regarding monitoring (aim 2). DESIGN: Observati...
#1Simone P. Rauh (VU: VU University Amsterdam)H-Index: 10
#2Martijn W. Heymans (VU: VU University Amsterdam)H-Index: 67
Last. Jenny T. van der Steen (Radboud University Nijmegen)H-Index: 45
view all 7 authors...
BACKGROUND: We aimed to find the best predictive model for 14-day mortality in antibiotic-treated nursing home residents with dementia and pneumonia by first applying an existing model to the recent PneuMonitor study. Second, we evaluated whether model performance improved by revising variables or adding variables related to recent changes in the care for older people. METHODS: The original prognostic model included gender, respiratory rate, respiratory difficulty, pulse rate, decreased alertnes...
#1Robert W. Koivula (University of Oxford)H-Index: 11
#2Ian M Forgie (Dund.: University of Dundee)H-Index: 5
Last. Femke Rutters (VUmc: VU University Medical Center)H-Index: 19
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Aims/hypothesis Here, we describe the characteristics of the Innovative Medicines Initiative (IMI) Diabetes Research on Patient Stratification (DIRECT) epidemiological cohorts at baseline and follow-up examinations (18, 36 and 48 months of follow-up).
#1Anitra D.M. Koopman (PHRI: Public Health Research Institute)H-Index: 10
#2Joline W.J. BeulensH-Index: 64
Last. Femke RuttersH-Index: 19
view all 8 authors...
Abstract Context Antibodies to the 65 kD isoform of glutamic acid decarboxylase (GAD65) have been associated with incident Type 2 Diabetes Mellitus, however results are inconsistent. Objective To assess the association between GAD65 antibody positivity and incident Type 2 Diabetes Mellitus in a non-diabetic adult (≥18 years) population, in a systematic review and meta-analysis. Data Sources A systematic literature search was conducted in Pubmed (MEDLINE) and Embase until January 14th, 2019. Stud...
#5Neil R. Robertson (University of Oxford)H-Index: 20
OBJECTIVE Gastrointestinal adverse effects occur in 20–30% of patients with metformin-treated type 2 diabetes, leading to premature discontinuation in 5–10% of the cases. Gastrointestinal intolerance may reflect localized high concentrations of metformin in the gut. We hypothesized that reduced transport of metformin via the plasma membrane monoamine transporter (PMAT) and organic cation transporter 1 (OCT1) could increase the risk of severe gastrointestinal adverse effects. RESEARCH DESIGN AND ...
#1Sytske van Bruggen (LUMC: Leiden University Medical Center)H-Index: 3
#2Simone P. Rauh (VU: VU University Amsterdam)H-Index: 10
Last. Mattijs E. Numans (LUMC: Leiden University Medical Center)H-Index: 19
view all 6 authors...
Objective Management of type 2 diabetes mellitus (T2DM) requires frequent monitoring of patients. Within a collective care group setting, doubts on the clinical effects of registration are a barrier for full adoption of T2DM registration in general practice. We explored whether full monitoring of biomedical and lifestyle-related target indicators within a care group approach is associated with lower HbA 1c levels. Design Observational, real-life cohort study. Setting Primary care data registry f...
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