Rajiv Chaturvedi
University of Toronto
Internal medicineRadiologyBalloonSurgeryMagnetic resonance imagingCardiologyFetusHemodynamicsCardiac catheterizationStentTetralogy of FallotVentricleHypoplastic left heart syndromeStenosisHeart diseaseAngioplastyPercutaneousPulmonary arteryAnesthesiaMedicine
116Publications
27H-index
2,103Citations
Publications 102
Newest
#1Sok-Leng Kang (Boston Children's Hospital)H-Index: 1
#1Sok-Leng Kang (Boston Children's Hospital)H-Index: 5
Last. Rajiv Chaturvedi (U of T: University of Toronto)H-Index: 27
view all 3 authors...
Abstract Background Creation of a Potts shunt, a connection between the left pulmonary artery (LPA) and descending aorta (DAo), improves functional status and survival in drug-refractory suprasystemic pulmonary arterial hypertension. We investigated a new approach to transcatheter Potts shunt creation in pigs. Methods and results In six pigs, a steerable SureFlex sheath was used to optimize the trajectory of perforation from the DAo into LPA using a 0.035″ radiofrequency wire. The combination of...
1 CitationsSource
#1Ali Alsagheir (McMaster University)H-Index: 5
#2Alex Koziarz (U of T: University of Toronto)H-Index: 8
Last. Osami HonjoH-Index: 22
view all 9 authors...
Abstract Objective The aim of this systematic review and meta-analysis is to evaluate whether duct stenting (DS) is associated with better survival and other clinical outcomes compared to modified Blalock-Taussig shunt (BTS) in infants with a duct-dependent pulmonary flow. Methods A systematic search of Medline, Embase, and Cochrane databases was performed by four independent reviewers from inception to March 2019. Meta-analysis was performed using DerSimonian and Laird method with inverse-varia...
7 CitationsSource
#1Juan Pablo Sandoval (U of T: University of Toronto)H-Index: 6
#2Sok-Leng Kang (U of T: University of Toronto)H-Index: 2
Last. Rajiv Chaturvedi (U of T: University of Toronto)H-Index: 27
view all 6 authors...
Background: Balloon angioplasty for native coarctation of the aorta (CoA) is successful in children and adults but in neonates results in frequent restenosis. The efficacy of balloon angioplasty fo...
1 CitationsSource
#1Juan Contreras (U of T: University of Toronto)H-Index: 2
#2Badr Bannan (U of T: University of Toronto)
Last. David J. Barron (U of T: University of Toronto)H-Index: 2
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Neoaortic root dilation is a common phenomenon after the Norwood procedure, but the real incidence and its natural history are unclear. Regular surveillance in these patients after the operation is necessary. Herein, we present an 11-year-old boy born with tricuspid atresia, a discordant ventriculo-arterial connection and a hypoplastic aortic arch, who was palliated initially with a hybrid stage I procedure involving a reversed Blalock-Taussig shunt, followed by comprehensive stage II and then, ...
Source
#1Roozbeh ManshaeiH-Index: 6
#2Daniele MericoH-Index: 44
Last. Anne S. Bassett (CAMH: Centre for Addiction and Mental Health)H-Index: 65
view all 23 authors...
Recent genome-wide studies of rare genetic variants have begun to implicate novel mechanisms for tetralogy of Fallot (TOF), a severe congenital heart defect (CHD). To provide statistical support for case-only data without parental genomes, we re-analyzed genome sequences of 231 individuals with TOF (n = 175) or related CHD. We adapted a burden test originally developed for de novo variants to assess ultra-rare variant burden in individual genes, and in gene-sets corresponding to functional pathw...
3 CitationsSource
#1Sok-Leng Kang (U of T: University of Toronto)H-Index: 2
#2Nicholas Shkumat (U of T: University of Toronto)H-Index: 2
Last. Lee N. Benson (U of T: University of Toronto)H-Index: 74
view all 10 authors...
Digital reality is an emerging platform for three-dimensional representation of medical imaging data. In this technical innovation paper, the authors evaluated the accuracy and utility of mixed-reality technology in the morphological evaluation of complex congenital heart disease. The authors converted CT datasets of 12 heart specimens with different subtypes of double-outlet right ventricle to stereoscopic images and interrogated them using a mixed-reality system. The morphological features ide...
1 CitationsSource
#1Roozbeh ManshaeiH-Index: 6
#2Daniele MericoH-Index: 44
Last. Anne S. Bassett (CAMH: Centre for Addiction and Mental Health)H-Index: 65
view all 20 authors...
Recent genome-wide studies of rare genetic variants have begun to implicate novel mechanisms for tetralogy of Fallot (TOF), a severe congenital heart defect (CHD). To provide statistical support for case-only data without parental genomes, we re-analyzed genome sequences of 231 individuals with TOF or related CHD. We adapted a burden test originally developed for de novo variants to assess singleton variant burden in individual genes, and in gene-sets corresponding to functional pathways and mou...
Source
#1Miriam S. ReuterH-Index: 18
#1Miriam S. ReuterH-Index: 5
Last. Rebekah JoblingH-Index: 14
view all 23 authors...
This study investigated the diagnostic utility of nontargeted genomic testing in patients with pediatric heart disease. We analyzed genome sequencing data of 111 families with cardiac lesions for rare, disease-associated variation. In 14 families (12.6%), we identified causative variants: seven were de novo (ANKRD11, KMT2D, NR2F2, POGZ, PTPN11, PURA, SALL1) and six were inherited from parents with no or subclinical heart phenotypes (FLT4, DNAH9, MYH11, NEXMIF, NIPBL, PTPN11). Outcome of the test...
11 CitationsSource
#1Rajiv ChaturvediH-Index: 27
#2Johannes Keunen (MSH: Mount Sinai Hospital, Toronto)H-Index: 13
Last. Edgar Jaeggi (Hospital for Sick Children)H-Index: 49
view all 5 authors...
Source
#1L.K. Taniguchi (U of T: University of Toronto)H-Index: 1
#2Christoph Haller (U of T: University of Toronto)H-Index: 6
Last. Janna L. Morrison (UniSA: University of South Australia)H-Index: 40
view all 18 authors...
1 CitationsSource