Du-Fang Ma
Shandong University of Traditional Chinese Medicine
Cardiac function curveInternal medicineEndocrinologyTyrosine hydroxylaseCardiologyChemistryTraditional Chinese medicineCholine acetyltransferaseLeukemia inhibitory factorDenervationInflammationAutonomic nervous systemHeart failureNerve growth factorSympathectomyStreptozotocinQuercetinGuizhi decoctionCardiac autonomic neuropathyRat modelAnesthesiaCiliary neurotrophic factorHeart rate variabilityMedicineBlood pressurePharmacology
15Publications
6H-index
89Citations
Publications 15
Newest
#1Zhao-Yu Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 2
#2Yong-Cheng Wang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 5
Last. Xiao Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
view all 11 authors...
Objective The anatomical and functional imbalances of sympathetic nerves are associated with cardiovascular disease progression. Xiao-Qing-Long-Tang (XQLT), an ancient Chinese herbal formula, has been used to treat cardiovascular diseases in eastern Asia for thousands of years. We determined the effect of XQLT in maintaining cardiac function during heart failure with reduced ejection fraction (HFrEF) with respect to its neurobiological effects in salt-sensitive rats. Methods Dahl salt-sensitive ...
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#1Yue-Hua Jiang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 10
#2Ling-Yu Jiang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 1
Last. Xiao Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
view all 5 authors...
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#1Yue-Hua Jiang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 10
#2Ling-Yu Jiang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 1
Last. Xiao Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
view all 5 authors...
Background and Aims: Endothelial senescence is an important risk factor leading to atherosclerosis. The mechanism of quercetin against endothelial senescence is worth exploring. Methods: Quercetin (20 mg/kg/d) was administered to ApoE-/- mice intragastrically to evaluate the effectiveness of quercetin on atherosclerotic lesion in vivo. In vitro, human aortic endothelial cells (HAECs) were used to assess the effect of quercetin on cellular senescence induced by oxidized low-density lipoprotein (o...
11 CitationsSource
#1Yong-Cheng Wang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 5
#2Du-Fang Ma (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
Last. Xiao Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
view all 8 authors...
Objective To observe the imbalance of anatomical and functional innervation factors of sympathetic nerves, nerve growth factor (NGF) and leukemia inhibitory factor (LIF), in salt-sensitive hypertensive heart failure rats and to explore the effects of treatment with Guizhi Decoction (桂枝汤) on sympathetic remodeling by inhibiting cholinergic transdifferentiation.
5 CitationsSource
#1Guofeng Zhou (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 3
#2Yue-Hua Jiang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 10
Last. Xiao Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
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Background. Changes in the gut microbiota are associated with cardiovascular disease progression. Xiao-Qing-Long Tang (XQLT), a traditional herbal formula, has an anti-inflammatory effect and regulates the steady state of the immune system, which is also associated with the progression of heart failure with preserved ejection faction (HFpEF). In this study, we investigated whether XQLT could contribute to prevent the development of HFpEF and whether the modulation of the gut microbiota by this h...
6 CitationsSource
#1Du-Fang Ma (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
#2Yong Wang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 1
Last. Xiao Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
view all 5 authors...
: Chronic low-grade inflammation is now widely accepted as one of the most important contributors to metabolic disorders. Glycoprotein 130 (gp130) cytokines are involved in the regulation of metabolic activity. Studies have shown that several gp130 cytokines, such as interleukin-6 (IL-6), leukemia inhibitory factor (LIF), oncostatin M (OSM), ciliary neurotrophic factor (CNTF), and cardiotrophin-1 (CT-1), have divergent effects on adipogenesis, lipolysis, and insulin sensitivity as well as food i...
7 CitationsSource
#1Yong-Cheng WangH-Index: 5
#2Du-Fang MaH-Index: 6
Last. Xiao LiH-Index: 6
view all 6 authors...
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#1Ping Jiang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 5
#2Du-Fang Ma (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
Last. Xiao Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
view all 8 authors...
: Low-grade pro-inflammatory state and leptin resistance are important underlying mechanisms that contribute to obesity-associated hypertension. We tested the hypothesis that Astragaloside IV (As IV), known to counteract obesity and hypertension, could prevent obesity-associated hypertension by inhibiting pro-inflammatory reaction and leptin resistance. High-fat diet (HFD) induced obese rats were randomly assigned to three groups: the HFD control group (HF con group), As IV group, and the As IV ...
22 CitationsSource
#1Xiao Li (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
#2Du-Fang Ma (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 6
Last. Ping Jiang (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 5
view all 6 authors...
Nicotine, as a non-selective agonist of α7 nicotinic acetylcholine receptor (α7nAChR), has been shown to possess anti-obesity and anti-hypertension properties; however, it is not applicable due to its adverse effects. We tested the hypothesis that Astragaloside IV (As IV), known to counteract
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