Lisa Delano-Wood
University of California, San Diego
PsychiatryInternal medicineNeuropsychologyOncologyPsychologyCardiologyNeuroscienceCognitionDiseaseDementiaTraumatic brain injuryWhite matterCognitive declineCognitive impairmentAlzheimer's diseaseAudiologyApolipoprotein ENeuroimagingClinical psychologyMedicine
160Publications
32H-index
3,891Citations
Publications 156
Newest
#1Katherine J. Bangen (Veterans Health Administration)H-Index: 29
#2Denis S. Smirnov (UCSD: University of California, San Diego)H-Index: 4
Last. Douglas Galasko (UCSD: University of California, San Diego)H-Index: 125
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Background null Arterial stiffening has emerged as an important risk factor for Alzheimer's disease (AD) and related dementias. Carotid-femoral pulse wave velocity has been proposed as a non-invasive and reproducible method to assess arterial stiffness. However, the association of pulse wave velocity with performance across multiple cognitive domains as well as interactions with in vivo AD biomarkers and apolipoprotein E (APOE) genotype has received limited study. null Method null We studied 193...
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#1McKenna S. Sakamoto (UCSD: University of California, San Diego)
#2Lisa Delano-Wood (UCSD: University of California, San Diego)H-Index: 32
Last. Victoria C. MerrittH-Index: 13
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OBJECTIVE To examine the association between employment status and neuropsychological functioning in veterans with a history of remote mild traumatic brain injury (mTBI) using 2 approaches to assess cognitive performance: (a) standard, traditional mean cognitive performance; and (b) across-test intraindividual variability (IIV). SETTING Outpatient Veterans Affairs (VA) hospital. PARTICIPANTS Eligibility criteria included veterans with a history of mTBI who performed adequately on performance val...
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#1Katherine J. Bangen (Veterans Health Administration)H-Index: 29
#2Kelsey R. Thomas (Veterans Health Administration)H-Index: 15
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INTRODUCTION Neurofilament light (NFL) reflects neuroaxonal damage and is implicated in mild cognitive impairment (MCI) and Alzheimer's disease (AD). Little is known about NFL in pre-MCI stages, such as in individuals with objectively-defined subtle cognitive decline (Obj-SCD). METHODS Two hundred ninety-four participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI) underwent baseline blood draw and serial neuropsychological testing over 5 years of follow-up. RESULTS Individuals w...
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OBJECTIVE We examined whether intraindividual variability (IIV) across tests of executive functions (EF-IIV) is elevated in Veterans with a history of mild traumatic brain injury (mTBI) relative to military controls (MCs) without a history of mTBI. We also explored relationships among EF-IIV, white matter microstructure, and posttraumatic stress disorder (PTSD) symptoms. METHOD A total of 77 Veterans (mTBI = 43, MCs = 34) completed neuropsychological testing, diffusion tensor imaging (DTI), and ...
2 CitationsSource
#1Lisa V. Graves (SDSU: San Diego State University)H-Index: 4
#2Stephanie M. Simone (UCSD: University of California, San Diego)
Last. Paul E. Gilbert (SDSU: San Diego State University)H-Index: 32
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: The original and second editions of the California Verbal Learning Test (CVLT) used nonparametric and parametric methods, respectively, to assess Total Recognition Discriminability (RD). In a previous study, we found evidence that the nonparametric formula may be more sensitive than the parametric formula to high false positive (FP) rates and provide more accurate assessments of yes/no recognition in neurodegenerative populations prone to high FP rates, including Alzheimer's disease (AD). In t...
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#1Katherine J. BangenH-Index: 29
#2Lisa Delano-Wood (UCSD: University of California, San Diego)H-Index: 32
Last. Melissa Lamar (Rush University Medical Center)H-Index: 30
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Alterations to cerebral white matter tracts have been associated with cognitive decline in aging and Alzheimer's disease (AD). In particular, the fornix has been implicated as especially vulnerable given that it represents the primary outflow tract of the hippocampus. Despite this, little work has focused on the fornix using a potential early marker of white matter degeneration-myelin water fraction (MWF; an in vivo marker of myelin content). Therefore, we sought to (1) clarify associations betw...
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#1Scott F. Sorg (UCSD: University of California, San Diego)H-Index: 16
#2Madeleine L. Werhane (UCSD: University of California, San Diego)H-Index: 9
Last. Lisa Delano-WoodH-Index: 32
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OBJECTIVE The evaluation of memory complaints in mild traumatic brain injury (mTBI) remains an important clinical consideration, especially in the context of comorbid psychiatric symptoms such as posttraumatic stress disorder (PTSD). We compared subjective memory complaints in veterans with and without a history of mTBI, examined ratings between those with single versus multiple mTBIs, and investigated associations between memory complaints and PTSD symptom severity. METHODS 117 outpatient veter...
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#1Erin E. Sundermann (University of California, Berkeley)H-Index: 16
#2Kelsey R. Thomas (University of California, Berkeley)H-Index: 15
Last. Lisa M. Delano-Wood (University of California, Berkeley)H-Index: 1
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Although type 2 diabetes is a well-known risk factor for Alzheimer’s disease (AD), little is known about how its precursor—prediabetes—impacts neuropsychological function and brain health. Thus, we examined the relationship between prediabetes and AD-related biological and cognitive/clinical markers in a well-characterized sample drawn from the Alzheimer’s Disease Neuroimaging Initiative. Additionally, because women show higher rates of AD and generally more atherogenic lipid profiles than men, ...
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#1Victoria C. MerrittH-Index: 13
Last. Lisa Delano-WoodH-Index: 32
view all 7 authors...
We examined the association between cognitive functioning and health-related quality of life (HR-QOL) in military Veterans with a history of mild traumatic brain injury (mTBI) using two methods to assess cognition: mean performance on cognitive composite scores and across-test intra-individual variability (IIV). The sample included 73 Veterans (84.9% male; age: M=32.47 years) who completed neuropsychological testing and self-report questionnaires approximately seven years post-injury. Three cogn...
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#1Alexandra L. Clark (UCSD: University of California, San Diego)H-Index: 13
#2Alexandra J. Weigand (UCSD: University of California, San Diego)H-Index: 8
Last. Lisa Delano-Wood (UCSD: University of California, San Diego)H-Index: 32
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Mild traumatic brain injury (mTBI) is a risk factor for Alzheimer’s disease (AD), and evidence suggests cerebrovascular dysregulation initiates deleterious neurodegenerative cascades. We examined w...
2 CitationsSource