Linda K. McEvoy
University of California, San Diego
Internal medicinePathologyMagnetic resonance imagingPsychologyNeuroscienceCognitionWorking memoryAlzheimer's Disease Neuroimaging InitiativeDiseaseDementiaAtrophyCognitive declineAlzheimer's diseaseElectroencephalographyAudiologyApolipoprotein EMedicineGerontologyBiologyEpisodic memory
196Publications
66H-index
11.5kCitations
Publications 193
Newest
#1Min-Tzu Lo (UCSD: University of California, San Diego)H-Index: 14
#2Karolina Kauppi (UCSD: University of California, San Diego)H-Index: 17
Last. Chi-Hua Chen (UCSD: University of California, San Diego)H-Index: 34
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Abstract The risk of APOE for Alzheimer's disease (AD) is modified by age. Beyond APOE, the polygenic architecture may also be heterogeneous across age. We aim to investigate age-related genetic heterogeneity of AD and identify genomic loci with differential effects across age. Stratified gene-based genome-wide association studies and polygenic variation analyses were performed in the younger (60–79 years, N = 14,895) and older (≥80 years, N = 6559) age-at-onset groups using Alzheimer's Disease ...
11 CitationsSource
#1Linda K. McEvoy (UCSD: University of California, San Diego)H-Index: 66
#2Linda K McEvoy (UCSD: University of California, San Diego)
Last. Jaclyn Bergstrom (UCSD: University of California, San Diego)H-Index: 23
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Source
#1Riki E Slayday (SDSU: San Diego State University)
#2Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
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Source
#1Sindana D. Ilango (UCSD: University of California, San Diego)H-Index: 6
#2Linda K. McEvoyH-Index: 66
Last. Donna Kritz-SilversteinH-Index: 55
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OBJECTIVE: The aim of the study was to examine the association of pregnancy history with trajectories of cognitive function in older women. METHODS: Participants were 1,025 women (mean age = 73.1 ± 9.6 y) enrolled in the Rancho Bernardo Study who attended a clinic visit between 1988 and 1992, when pregnancy history (ever pregnant, number of pregnancies, ages at first and last pregnancy) was recorded and cognitive function was assessed with a battery of four tests repeated up to 7 times through 2...
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#1Sarah J. Banks (UCSD: University of California, San Diego)H-Index: 21
#2Leonardino A. Digma (UCSD: University of California, San Diego)H-Index: 2
Last. James B. Brewer (UCSD: University of California, San Diego)H-Index: 50
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Source
#1William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
#2Jeremy A. Elman (UCSD: University of California, San Diego)H-Index: 15
Last. Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
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#1Emilie T. ReasH-Index: 13
#2Donald J. HaglerH-Index: 88
Last. James B. BrewerH-Index: 50
view all 11 authors...
Source
#1Jeremy A. Elman (UCSD: University of California, San Diego)H-Index: 15
#2Matthew S. Panizzon (UCSD: University of California, San Diego)H-Index: 35
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
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Author(s): Elman, JA; Panizzon, MS; Gillespie, NA; Hagler, DJ; Fennema-Notestine, C; Eyler, LT; McEvoy, LK; Neale, MC; Lyons, MJ; Franz, CE; Dale, AM; Kremen, WS | Abstract: The human hippocampus can be subdivided into subfields with unique functional properties and differential vulnerability to disease or neuropsychiatric conditions. Identifying genes that confer susceptibility to such processes is an important goal in developing treatments. Recent advances in automatic subfield segmentation fr...
8 CitationsSource
#1Emilie T. Reas (UCSD: University of California, San Diego)H-Index: 13
#2Gail A. Laughlin (UCSD: University of California, San Diego)H-Index: 65
Last. Linda K. McEvoy (UCSD: University of California, San Diego)H-Index: 66
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BACKGROUND: physical activity in older age has been associated with better cognitive function, but the role of earlier life physical activity is less well understood. OBJECTIVE: determine associations between physical activity throughout the lifespan and cognitive function in older age. DESIGN: cross-sectional study. SETTING: the Rancho Bernardo Study of Healthy Aging in southern California. SUBJECTS: A total of 1,826 community-dwelling men and women (60-99 years) who attended a research visit i...
11 CitationsSource
#1Iris J. Broce (UCSF: University of California, San Francisco)H-Index: 9
#2Chin Hong Tan (NTU: Nanyang Technological University)H-Index: 15
Last. Rahul S. Desikan (UCSF: University of California, San Francisco)H-Index: 43
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Cardiovascular (CV)- and lifestyle-associated risk factors (RFs) are increasingly recognized as important for Alzheimer’s disease (AD) pathogenesis. Beyond the e4 allele of apolipoprotein E (APOE), comparatively little is known about whether CV-associated genes also increase risk for AD. Using large genome-wide association studies and validated tools to quantify genetic overlap, we systematically identified single nucleotide polymorphisms (SNPs) jointly associated with AD and one or more CV-asso...
45 CitationsSource