Alexander C. Egbe
Mayo Clinic
Internal medicineSurgeryCardiologyRetrospective cohort studyHemodynamicsHazard ratioHeart failureTetralogy of FallotVentricleAtrial fibrillationAortaHeart diseasePulmonary arteryPopulationIn patientIncidence (epidemiology)DiastoleMedicineCohortEjection fractionBlood pressure
187Publications
20H-index
1,417Citations
Publications 183
Newest
#1William R. Miranda (Mayo Clinic)H-Index: 14
#2Donald J. Hagler (Mayo Clinic)H-Index: 88
Last. Alexander C. Egbe (Mayo Clinic)H-Index: 20
view all 6 authors...
OBJECTIVE: To assess the association between elevated ventricular-end diastolic pressures (VEDP) and pulmonary artery wedge pressure (PAWP) on long-term survival in adult Fontan patients. BACKGROUND: The impact of ventricular filling pressures on long-term survival in adults post-Fontan palliation is unknown. METHODS: We included 148 adult Fontan patients (age ≥ 18 years) without atrioventricular valve prosthesis or pulmonary vein stenosis undergoing arterial and venous catheterization between D...
1 CitationsSource
#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2Rahul Vojjini (Mayo Clinic)H-Index: 2
Last. Nathaniel W. Taggart (Mayo Clinic)H-Index: 14
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Abstract Background Inferior vena cava (IVC) size and collapsibility provides a noninvasive estimate of right heart filling pressures, an important determinant of right heart hemodynamic performance that is not measured by cardiac magnetic resonance imaging (CMRI). We hypothesized that compared to CMRI risk model alone, a combined CMRI-IVC risk model will have better correlation with disease severity and peak oxygen consumption (VO2) in patients with tetralogy of Fallot (TOF). Methods Retrospect...
1 CitationsSource
#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2Yogesh N.V. Reddy (Mayo Clinic)H-Index: 26
Last. Barry A. Borlaug (Mayo Clinic)H-Index: 76
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Background: Patients with vascular stiffening may display increased arterial afterload that is out of proportion to systolic blood pressure (SBP). Since vascular and endothelial dysfunction develop...
5 CitationsSource
#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2Keerthana Banala (Mayo Clinic)H-Index: 3
Last. Naser M. Ammash (Mayo Clinic)H-Index: 35
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Abstract Background Left heart filling pressures, as measured by pulmonary artery wedge pressure (PAWP), is associated with heart failure related mortality. Because of the prognostic importance of PAWP, several echocardiographic indices have been proposed for noninvasive assessment of PAWP. However, these indices have not been validated in the congenital heart disease population. The purpose of this study was to determine the correlation between echocardiographic indices of PAWP, and the effect ...
Source
#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2Maria Najam (Mayo Clinic)H-Index: 4
Last. Deshmukh Abhishek (Mayo Clinic)H-Index: 1
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Abstract Background Prevalence of pacemaker-induced cardiomyopathy (PICM) in adults with congenital heart disease is unknown. Tetralogy of Fallot (TOF) is a common diagnosis in the adult congenital heart disease population, and the purpose of this study was to determine association between frequent right ventricular (RV) pacing and temporal decrease in left ventricular ejection fraction (LVEF) from pre-implantation to 2-years post-implantation (LVEFpost-pre) in TOF patients. Methods We studied T...
1 CitationsSource
#1Masaru Obokata (Mayo Clinic)H-Index: 22
#2Garvan C. Kane (Mayo Clinic)H-Index: 50
Last. Barry A. Borlaug (Mayo Clinic)H-Index: 76
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Introduction Identification of elevated pulmonary artery (PA) pressures during exercise has important diagnostic, prognostic, and therapeutic implications. Stress echocardiography is frequently used to estimate PA pressures during exercise testing, but data supporting this practice are limited. This study examined the accuracy of Doppler echocardiography for the estimation of PA pressures at rest and during exercise. Methods Simultaneous cardiac catheterisation-echocardiographic studies were per...
8 CitationsSource
#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2Muhammad Yasir Qureshi (Mayo Clinic)H-Index: 10
Last. Heidi M. Connolly (Mayo Clinic)H-Index: 75
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Background: Coarctation of aorta (COA) results in chronic left ventricular (LV) pressure overload and subsequently leads to LV diastolic dysfunction and heart failure over time. The goal of COA int...
2 CitationsSource
#1Alexander C. Egbe (Mayo Clinic)H-Index: 20
#2Keerthana Banala (Mayo Clinic)H-Index: 3
Last. Naser M. Ammash (Mayo Clinic)H-Index: 35
view all 8 authors...
Abstract Cardiac magnetic resonance imaging derived right ventricular (RV) volumes are often necessary for optimal timing of pulmonary valve replacement in patients with tetralogy of Fallot (TOF). This practice is based on previous studies that reported preoperative RV volumetric thresholds that predicted postoperative RV remodeling. As a result, pulmonary valve replacements are being performed even in asymptomatic patients based on RV volumetric thresholds that predict complete postoperative RV...
1 CitationsSource
#1Saraschandra Vallabhajosyula (Mayo Clinic)H-Index: 23
#1Saraschandra Vallabhajosyula (Mayo Clinic)H-Index: 8
Last. Abhishek DeshmukhH-Index: 35
view all 11 authors...
Refractory ventricular tachycardia (VT) and electrical storm are frequently associated with hemodynamic compromise requiring mechanical support. This study sought to review the current literature on the use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) for hemodynamic support during VT ablation. This was a systematic review of all published literature from 2000 to 2019 evaluating patients with VT undergoing ablation with VA-ECMO support. Studies that reported mortality, safety, a...
12 CitationsSource
#1H. Yang (UvA: University of Amsterdam)H-Index: 5
Last. B. J. M. Mulder (UvA: University of Amsterdam)H-Index: 1
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Abstract Background Current guidelines consider vitamin K antagonists (VKA) the oral anticoagulant agents of choice in adults with atrial arrhythmias (AA) and moderate or complex forms of congenital heart disease, significant valvular lesions, or bioprosthetic valves, pending safety data on non-VKA oral anticoagulants (NOACs). Therefore, the international NOTE registry was initiated to assess safety, change in adherence and quality of life (QoL) associated with NOACs in adults with congenital he...
20 CitationsSource