Valeria Landoni
University of Rome Tor Vergata
PhysicsInternal medicineRadiologyUrologySurgeryOncologyDose fractionationDark matterScintillatorNuclear physicsMedical physicsProstateProstate cancerRectumToxicityNuclear medicineRadiation therapyBreast cancerMedicineDosimetry
80Publications
20H-index
1,517Citations
Publications 79
Newest
PURPOSE The purpose of this study is to evaluate inter- and intra-fraction organ motion as well as to quantify clinical target volume (CTV) to planning target volume (PTV) margins to be adopted in the stereotactic treatment of early stage glottic cancer. METHODS AND MATERIALS Stereotactic body radiotherapy (SBRT) to 36 Gy in 3 fractions was administered to 23 patients with early glottic cancer T1N0M0. Patients were irradiated with a volumetric intensity modulated arc technique delivered with 6 M...
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#1Giuseppe SanguinetiH-Index: 37
#2Raul PelliniH-Index: 21
Last. Valeria LandoniH-Index: 20
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AIM Because the clinical feasibility of stereotactic body radiotherapy (SBRT) for early glottic cancer (T1) is controversial, we report dosimetric results in 27 consecutive patients from a prospective phase I and II study that started in 2017. METHODS In our approach, only the parts of the true vocal cord containing cancer and those immediately adjacent are planned to be treated to 36 Gy and 30 Gy, respectively, in 3 fractions. Several dosimetric metrics for both target volumes and organs at ris...
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Abstract Purpose To assess the toxicity profile of prostate cancer stereotactic radiotherapy (SBRT) in 3 fractions. Methods and Materials This is a prospective, multicenter phase II toxicity study enrolling patients with low to favorable intermediate risk prostate cancer. Before simulation 3-4 fiducial markers along with a rectal spacer were placed. The target (prostate only) was prescribed 40 Gy, while the maximum dose to the urethra was limited to 33 Gy with the highest priority at planning; l...
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#1Andrea BresolinH-Index: 1
#2A. FaiellaH-Index: 5
Last. Cesare CozzariniH-Index: 43
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Abstract Background and purpose To assess bowel dose-volume relationships for acute patient-reported intestinal symptoms of patients treated with whole-pelvis intensity-modulated radiotherapy (WPRT) for prostate cancer. Materials and methods Complete data of 415 patients enrolled in a multi institute, prospective trial (#NCT02803086) treated with radical (31%), adjuvant (33%) and salvage (36%) intent at a median dose to pelvic nodes/lymph-nodal area of 53Gy were available. The most severe change...
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#1Giuseppe SanguinetiH-Index: 37
#2Luca BertiniH-Index: 1
Last. Valeria LandoniH-Index: 20
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OBJECTIVE: To assess the predictive role of response on dynamic contrast enhancement on magnetic resonance imaging (DCE-MRI) of visible local lesions in the setting of salvage radiotherapy (sRT) after radical prostatectomy. METHODS: All patients referred for sRT for biochemical failure after radical prostatectomy from February 2014 to September 2016 were considered eligible if they had been restaged with DCE-MRI and had been found to have a visible lesion in the prostatic bed, but no distant/nod...
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Abstract Background and purpose Dose-volume objectives for the rectum have been proposed to limit long term toxicity after moderately hypofractionated radiotherapy (MHRT) for localized prostate cancer. The purpose of the present study is to validate and possibly refine dose volume objective for the rectal wall after 20-fraction MHRT. Materials and methods All patients treated by 20-fraction MHRT at a single Institution were identified and relative rectal wall (%RW) DVH retrieved. The endpoint of...
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#1Valentina PinziH-Index: 11
#2Valeria LandoniH-Index: 20
Last. Roberto Orecchia (IEO: European Institute of Oncology)H-Index: 71
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Background: The role of radiotherapy and brachytherapy in the management of locally advanced cervical and endometrial cancer is well established. However, in some cases, intracavitary brachytherapy (ICBRT) is not recommended or cannot be carried out. We aimed to investigate whether external-beam irradiation delivered by means of intensity-modulated radiation therapy (IMRT) might replace ICBRT in gynaecological cancer when the standard ICBRT boost delivering cannot be administered for technical o...
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#1Pietro GabrieleH-Index: 23
#2Fernando MunozH-Index: 11
Last. Cesare CozzariniH-Index: 43
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#1Giuseppe SanguinetiH-Index: 37
#2Alessia FarnetiH-Index: 9
Last. Alessandro MagliH-Index: 12
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#1Angelo MaggioH-Index: 11
#2Tiziana RancatiH-Index: 27
Last. Cesare CozzariniH-Index: 43
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