Satoru Ozaki
Kanazawa University
EndocrinologyInnate immune systemPathologyMolecular biologyReceptorImmunohistochemistryBiliary tractCongenital hepatic fibrosisAdventitiaCervical cancerBile ductCaroli diseasePolycystic kidney diseasePrimary biliary cirrhosisFibrosisIntrahepatic bile ductsBiliary cirrhosisCancer researchMedicineBiology
31Publications
19H-index
1,040Citations
Publications 31
Newest
#1Satomi Kasashima (Kanazawa University)H-Index: 21
#2Atsuhiro KawashimaH-Index: 25
Last. Satoru Ozaki (Kanazawa University)H-Index: 19
view all 5 authors...
A 78-year-old male was admitted to our hospital with lumbar pain and was found to have an abdominal aortic aneurysm (AAA) and femoral artery aneurysm (FAA). Initially, the patient underwent endovascular aneurysm repair (EVAR) for the AAA and aneurysmectomy for the FAA. The FAA was diagnosed by histology as immunoglobulin G4-related disease (IgG4-RD). The preoperative serum IgG4 level was within the normal range, although a slight serum interleukin-6 (IL-6) elevation was observed. Four years late...
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#1Satomi Kasashima (Kanazawa University)H-Index: 21
#2Atsuhiro KawashimaH-Index: 25
Last. Hirofumi Takemura (Kanazawa University)H-Index: 16
view all 7 authors...
Abstract Objective Immunoglobulin G4 (IgG4)-related diseases are systemic inflammatory fibrous lesions characterized by elevated serum IgG4 and infiltration of IgG4-positive plasmacytes. They can manifest in vascular lesions as frequently formed aneurysms with prominent thickening of the adventitia (IgG4-related abdominal aortic aneurysm; IgG4-AAA). Matrix metalloproteinases (MMPs) degrade the extracellular matrix, mainly in the tunica media, resulting in destruction of aortic structures to caus...
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#1Satomi Kasashima (Kanazawa University)H-Index: 21
#2Atsuhiro KawashimaH-Index: 25
Last. Mitsutaka SuzukiH-Index: 1
view all 7 authors...
OBJECTIVE: Immunoglobulin (Ig)G4-related disease is a recently described systemic immune-mediated fibro-inflammatory disease that frequently occurs in tumorous form. Herein, we elucidated the clinicopathological and cytological characteristics of IgG4-related pleural lesions (PLs). PATIENTS AND METHODS: Among 22 patients with fibro-inflammatory PLs of idiopathic aetiology, eight cases were diagnosed as IgG4-PL and the remaining 14 as non-IgG4-PL according to comprehensive diagnostic criteria for...
3 CitationsSource
#1Satoru Ozaki (Kanazawa University)H-Index: 19
#2Satomi KasashimaH-Index: 21
Last. Akishi Ooi (Kanazawa University)H-Index: 32
view all 4 authors...
Myxoinflammatory fibroblastic sarcoma (MIFS) is rare low-grade soft-tissue tumor that occurs in extremities. Clinically it is difficult to differentiate from benign lesions, such as nodular fasciitis, and malignant tumors, such as liposarcoma. We report a case of MIFS in the forearm of a 34-year-old man. The resected tumor measured 5.3 × 2.7 × 2.5 cm3, had a lobular structure with indistinct boundary, and consisted of a large amount of translucent and yellow mucous-like substrate. Cytological ex...
1 CitationsSource
#1Satomi KasashimaH-Index: 21
#2Atsuhiro KawashimaH-Index: 25
Last. Kengo KawakamiH-Index: 11
view all 8 authors...
Abstract Objective Immunoglobulin (Ig) G4-related aortic aneurysms (IgG4-AAs) are a special aortic aneurysm among IgG4-related diseases (IgG4-RDs), which are inflammatory and fibrous conditions characterized by tumorous swelling of affected organs and high serum IgG4 concentrations. Recently, IgG4-RD pathogenesis was shown to be associated with T-helper-2 (Th2) and regulatory T (Treg) dominant cytokine production, such as interleukin (IL)-4, IL-10, and IL-13. IL-6 is a key proinflammatory cytoki...
28 CitationsSource
#1Satoru Ozaki (Kanazawa University)H-Index: 19
#2Yuji Mizukami (Kanazawa University)H-Index: 26
Last. Ei Kawahara (Kanazawa University)H-Index: 18
view all 3 authors...
We report four cases of adenoma of the nipple, a rare benign epithelial benign tumor occurring under the nipple and areola. Clinically, erosion findings of the nipple require discrimination from Paget's disease. In addition, a mass found in the nipple warrants discrimination from ductal carcinoma. Two cases underwent aspiration biopsy cytology and the other underwent tumor imprint cytology, respectively, revealing a large number of epithelial cell populations in the necrotic background material....
2 CitationsSource
#1Satoru Ozaki (Kanazawa University)H-Index: 19
#2Ei Kawahara (Kanazawa University)H-Index: 18
Last. Seiji Yano (Kanazawa University)H-Index: 41
view all 8 authors...
The insulin-like growth factor 2 gene (IGF2) is an imprinting gene, which mediates cell growth and apoptosis. The loss of imprinting (LOI) of IGF2 has been associated with the development of cancer. In the present study, loss LOI of IGF2 in lung cancer was analyzed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in combination with DNA sequencing of samples collected by laser capture microdissection. The status of each sample was assigned as imprinting when PC...
2 CitationsSource
#1Satoru Ozaki (Kanazawa University)H-Index: 19
#2Kana KatoH-Index: 2
Last. Masaki Inoue (Kanazawa University)H-Index: 59
view all 8 authors...
Abstract Regional differences in human papillomavirus (HPV) genotypes and the presence of mixed HPV infections may affect adversely the efficacy of the HPV vaccine. Therefore, a simple and high-throughput HPV genotyping system is required. Recently, a novel HPV genotyping kit (the Mebgen™ HPV kit) was developed. This kit uses multiplex PCR and Luminex xMAP™ technology to detect 13 types of high-risk HPVs and an internal control in a 96-well format. In the present study, the analytical performanc...
25 CitationsSource
#1Yoshiaki Norimatsu (UHSA: University of Health Sciences Antigua)H-Index: 13
#2Shingo SakamotoH-Index: 3
Last. Tadao K. Kobayashi (Osaka University)H-Index: 20
view all 10 authors...
We compared the cytoarchitectural features used for the cytologic diagnosis of endometrial adenocarcinoma (EC) using ThinPrep® (TPS = ThinPrep Sample) and BD SurePath™ (SPS = SurePath Sample) preparations. In 20 patients, a direct endometrial sample using the Uterobrush was obtained. Nineteen cases of EA and one case of carcinosarcoma were studied. TPS and SPS were performed according to the manufacturer's recommendations. Moreover, after the TPS preparation, the residual material was also used ...
21 CitationsSource
#1Satoru Ozaki (Kanazawa University)H-Index: 19
#2Seiko KitamuraH-Index: 1
Last. Masaki InoueH-Index: 59
view all 8 authors...
Abstract Of the more than 100 strains of human papillomavirus (HPV) reported to date, 13 strains are clinically significant due to the highly associated risk of cervical cancer. HPV test reagents are currently being developed to aid detection of these strains. The present study compared a novel HPV genotyping reagent using a Luminex device, which enables simultaneous quantitation of multiple targets using fluorescent beads, and gene-specific multiplex polymerase chain reaction (Luminex method) w...
2 Citations