Teik Choon See
Cambridge University Hospitals NHS Foundation Trust
Internal medicineRadiologySurgeryMagnetic resonance imagingUltrasoundCardiologyRandomized controlled trialProspective cohort studyRadiological weaponAdverse effectPsychological interventionEmbolizationAneurysmRenal arteryEmbolectomyHepatectomyAortic aneurysmRadiofrequency ablationVascular diseaseHepatocellular carcinomaMagnetic resonance angiographySepsisStentAbdominal wallPortal veinThrombolysisLiver transplantationAortaAbdominal aortic aneurysmStenosisKidneyCalcificationAngioplastyAngiographyPercutaneousAbdominal painComputed tomography angiographyPercutaneous transhepatic biliary drainageTransplantationComputed tomographicSurgical repairIntraluminal thrombusWall stressIn patientPerioperativeRadiographyConfidence intervalPeripheralInterventional radiologyComputed tomographyMedical emergencyGeneral surgeryInformed consentMedicineComplication
Publications 52
#1Gregory C. Makris (St Thomas' Hospital)H-Index: 6
#1Gregory C. Makris (St Thomas' Hospital)H-Index: 14
Last. Andrew Wigham (University of Oxford)H-Index: 5
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The purpose of this study was to evaluate the predictive value of a ‘Modified Karnofsky Scoring System’ on outcomes and provide real-world data regarding the UK practice of biliary interventions. A prospective multi-centred cohort study was performed. The pre-procedure modified Karnofsky score, the incidence of sepsis, complications, biochemical improvement and mortality were recorded out to 30 days post procedure. A total of 292 patients (248 with malignant lesions) were suitable for inclusion ...
#1Fotios Sampaziotis (University of Cambridge)H-Index: 12
#2Daniele MuraroH-Index: 12
Last. Ludovic Vallier (University of Cambridge)H-Index: 58
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Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. We address this challenge using cholangiocyte organoids in the context of cholangiopathies, which represent a key reason for liver transplantation. Using single-cell RNA sequencing, we show that primary human cholangiocytes display transcriptional diversity that is lost in organoid culture. However, cholangiocyte organoids remain plastic and resume their in vivo signatures when transplanted ...
16 CitationsSource
As per the recently published British Society of Gastroenterology guideline, salvage transjugular intrahepatic portosystemic stent-shunt (TIPSS) is not recommended where the Child-Pugh score is >13 because of futility; however data is sparse, and case series have largely predated the use of covered stents and the modern era of Intensive Care management. Aim We sought to determine whether Child-Pugh score >13 is indeed a marker of futility in patients undergoing salvage TIPSS, and whether alterna...
#1James HawkenH-Index: 1
#2Sara UpponiH-Index: 7
Last. J.A. LeitheadH-Index: 3
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A 59-year-old woman presented to the emergency department of a hospital with tertiary hepatology services reporting upper abdominal pain and black stools. She was known to have alcohol-related cirrhosis (Child Pugh A6) under routine hepatology follow-up, and was an active drinker. Medical history included hypertension, hypothyroidism and a Roux-en-Y (RNY) gastric bypass for obesity 10 years previously. The patient was tachycardic but normotensive with melaena on digital rectal examination. Haemo...
#1Teik Choon See (Cambridge University Hospitals NHS Foundation Trust)H-Index: 12
Acute biliary conditions include cholangitis, obstruction, and biliary leakage. All these conditions may lead to severe biliary sepsis, which can be life threatening. Infected obstructed cholangitis is a medical emergency that requires active medical therapy and early biliary decompression is recommended. This article provides an overview of the clinical presentations and management of biliary sepsis. The technique, clinical applications, and outcomes of percutaneous transhepatic biliary drainag...
1 CitationsSource
#1Judith White (Cardiff and Vale University Health Board)H-Index: 11
#2Grace Carolan-Rees (Cardiff and Vale University Health Board)H-Index: 9
Last. Ricky A. Sharma (NIHR: National Institute for Health Research)H-Index: 27
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Abstract Purpose To evaluate the safety and efficacy of yttrium-90 transarterial radioembolization (TARE) for the treatment of unresectable, chemotherapy-refractory intrahepatic cholangiocarcinoma (ICC). Methods A prospective, observational study was carried out in 10 centers between 2013 and 2017. TARE plus standard care was delivered to patients with unresectable, chemotherapy-refractory or chemotherapy-intolerant ICC. Primary outcome was overall survival. Secondary outcomes included safety, p...
11 CitationsSource
#1Irum AminH-Index: 4
#2Neil RussellH-Index: 5
Last. Andrew J. ButlerH-Index: 45
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#1C. Miller (Leeds Teaching Hospitals NHS Trust)H-Index: 1
#2R. Frood (Leeds Teaching Hospitals NHS Trust)H-Index: 6
Last. C.J. Hammond (Leeds Teaching Hospitals NHS Trust)H-Index: 2
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AIM To provide an update of current practice in iliac artery intervention in the UK. MATERIALS AND METHODS Ninety-nine interventional units across the UK completed online submission forms for iliac angioplasty and stent procedures between 2011 and 2014 (inclusive) for the British Iliac Angioplasty and Stenting (BIAS) IV registry. RESULTS Data for 8,294 procedures were submitted during the study period. A total of 12,253 iliac segments were treated in 10,311 legs. The commonest indication was cla...
1 CitationsSource
#1Judith White (Cardiff and Vale University Health Board)H-Index: 11
#2Grace Carolan-Rees (Cardiff and Vale University Health Board)H-Index: 9
Last. Ricky A. Sharma (UCL: University College London)H-Index: 27
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Abstract Aims Patients with chemotherapy-refractory colorectal cancer liver metastases have limited therapeutic options. Selective internal radiation therapy (SIRT) delivers yttrium 90 microspheres as a minimally invasive procedure. This prospective, single-arm, observational, service-evaluation study was part of National Health Service England Commissioning through Evaluation. Methods Patients eligible for treatment had histologically confirmed carcinoma with liver-only/liver-dominant metastase...
10 CitationsSource