Tetsuo Himi
Sapporo Medical University
SurgeryPathologyMolecular biologyAntibodyReceptorTight junctionImmunologyOccludinOtitisMiddle earCytokineDiseaseIgG4-related diseasePathogenesisBarrier functionAudiologyMucous membrane of noseMedicineBiologyCell biology
406Publications
35H-index
4,587Citations
Publications 383
Newest
#1Tetsuji Takabayashi (University of Fukui)H-Index: 16
#2Daiya Asaka (Jikei University School of Medicine)H-Index: 15
Last. Shigeharu Fujieda (University of Fukui)H-Index: 35
view all 23 authors...
BackgroundStrong eosinophil infiltration in chronic rhinosinusitis with nasal polyp (CRSwNP) is highly associated with recalcitrance and higher nasal polyp recurrence rate after surgery. The preval...
Source
#1Akito Kakiuchi (Sapporo Medical University)H-Index: 3
#2Takuya Kakuki (Sapporo Medical University)H-Index: 8
Last. Takashi Kojima (Sapporo Medical University)H-Index: 44
view all 14 authors...
In human head and neck squamous cell carcinoma (HNSCC), the invasion and metastatic properties of cancer cells are promoted by junctional adhesion molecule‑A (JAM‑A) and claudin‑1; these are epithelial tight junction molecules regulated by histone deacetylases (HDACs) and transcription factor p63. HDAC expression is reportedly upregulated in HNSCC, and HDAC inhibitors suppress cancer cell proliferation by initiating proliferative arrest or apoptosis. However, little is known of the anti‑cancer m...
Source
#1Kenichi Takano (Sapporo Medical University)H-Index: 23
#2Aya Kaizaki (Sapporo Medical University)H-Index: 1
Last. Tetsuo Himi (Sapporo Medical University)H-Index: 35
view all 7 authors...
Purpose This study aims to describe the recommended equipment and procedures required for successful telefitting, based on our experience, document and evaluate patient satisfaction with telefittin...
Source
#1Risa Yadomura (Sapporo Medical University)
#2Sumito JitsukawaH-Index: 7
Last. Tetsuo Himi (Sapporo Medical University)H-Index: 35
view all 6 authors...
Source
#1Akira Yorozu (Sapporo Medical University)H-Index: 4
#2Tsuyoshi Okuni (Sapporo Medical University)H-Index: 2
Last. Tetsuo Himi (Sapporo Medical University)H-Index: 35
view all 6 authors...
Source
#1Noriko Ogasawara (NU: Northwestern University)H-Index: 17
#2Julie A. Poposki (NU: Northwestern University)H-Index: 13
Last. Atsushi Kato (NU: Northwestern University)H-Index: 56
view all 18 authors...
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by type 2 inflammation with accumulation of activated group 2 innate lymphoid cells (ILC2s) and elevation of thymic stromal lymphopoietin (TSLP). A member of the TNF superfamily (TNFSF), TNFSF15, is known to induce the production of type 2 cytokines in ILC2s. Although ILC2s have been implicated in CRSwNP, the presence and role of TNFSFs in ILC2-mediated type 2 inflammation in CRSwNP has not been elucidated. Here, we investigate t...
8 CitationsSource
#1Noriko Ogasawara (NU: Northwestern University)H-Index: 17
#2Julie A. Poposki (NU: Northwestern University)H-Index: 13
Last. Atsushi Kato (NU: Northwestern University)H-Index: 56
view all 16 authors...
TNF receptor II is expressed on ILC2s and TNF is able to induce production of type 2 cytokines in human ILC2s. TNF may play a role in causing or amplifying type 2 immunity contributing to health and disease.
3 CitationsSource
#1Motohisa Yamamoto (Sapporo Medical University)H-Index: 35
#2Kenichi Takano (Sapporo Medical University)H-Index: 23
Last. Hiroki Takahashi (Sapporo Medical University)H-Index: 9
view all 9 authors...
AbstractObjectives: Immunoglobulin (Ig) G4-related disease (IgG4-RD) is often complicated by allergic disorders. This study was conducted to investigate the mechanism of type 2 helper T-inflammatio...
2 CitationsSource
Source
#1Akito Kakiuchi (Sapporo Medical University)H-Index: 3
#2Takayuki Kohno (Sapporo Medical University)H-Index: 14
Last. Takashi Kojima (Sapporo Medical University)H-Index: 44
view all 12 authors...
Primary cilia, regulated via distinct signal transduction pathways, play crucial roles in various cellular behaviors. However, the full regulatory mechanism involved in primary cilia development du...
Source