Yubao Li
Sichuan University
Composite numberBiomedical engineeringNuclear chemistryComposite materialChemistryPolyamideMaterials scienceScanning electron microscopeBiocompatibilityBiomaterialBone tissuePolyurethaneChitosanBone regenerationCompressive strengthMembraneChemical engineeringPorosityBone healingScaffold
181Publications
31H-index
3,481Citations
Publications 185
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#1Miaomiao He (Sichuan University)H-Index: 3
#2Yong Huang (Sichuan University)H-Index: 3
Last. Li Zhang (Sichuan University)H-Index: 32
view all 8 authors...
Abstract Polyetheretherketone (PEEK) is a popular thermoplastic material widely used in engineering applications due to its favorable mechanical properties and stability at high temperatures. With the first implantable grade PEEK being commercialized in 1990s, the use of PEEK has since grown exponentially in the biomedical field and has rapidly transformed a large section of the medical devices landscape. Nowadays, PEEK is a standard biomaterial used across a wide range of implant applications, ...
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#1Wei Fang (Sichuan University)
#2Fuhua SunH-Index: 4
Last. Yubao Li (Sichuan University)H-Index: 31
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In order to improve the processability of conductive polyurethane (CPU) containing aniline oligomers, a new CPU containing aniline trimer (AT) and l-lysine (PUAT) are designed and synthesized. Further, the 3D porous PUAT membranes have been prepared by a simple gel cooperated with freeze-drying method. Chemical testings and conductive properties testify a self- doping model of PUAT based on the rich electronic l-lysine and electroaffinity AT moities. The self-doping behavior further endows the P...
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#1Shue Jin (Sichuan University)H-Index: 5
#2Xue Xia (Sichuan University)H-Index: 1
Last. Jidong Li (Sichuan University)H-Index: 17
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Bone regeneration is an interdisciplinary complex lesson, including but not limited to materials science, biomechanics, immunology, and biology. Having witnessed impressive progress in the past decades in the development of bone substitutes; however, it must be said that the most suitable biomaterial for bone regeneration remains an area of intense debate. Since its discovery, poly (lactic-co-glycolic acid) (PLGA) has been widely used in bone tissue engineering due to its good biocompatibility a...
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#1Jing Gao (Sichuan University)
#2Jinhui Huang (Sichuan University)H-Index: 2
Last. Jidong Li (Sichuan University)H-Index: 17
view all 9 authors...
Doxorubicin (Dox)-loaded or selenium-substituted hydroxyapatite (HA) has been developed to achieve anti-osteosarcoma or bone regeneration in a number of studies. However, currently, there is a lack of studies on the combination of Dox and selenium loading in/on HA and comparative research studies on which form and size of HA are more suitable for drug loading and release in the treatment osteogenesis after osteosarcoma resection. Herein, selenium-doped rod-shaped nano-HA (n-HA) and spherical mes...
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#1Lei Xiaoyu (Sichuan University)
#2Jian Wang (Sichuan University)H-Index: 3
Last. Yi Zuo (Sichuan University)H-Index: 25
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To solve the high instances of failure caused by endodontic reinfection, herein, an improved root filling material was produced to meet the multi-functional demand of sealers for root canal therapy. In this study, polyurethane (PU)-based nanocomposites were prepared by loading bismuth oxide, hydroxyapatite and antibacterial agents, namely Ag3PO4 and ZnO nanoparticles, which were named CP-Ag and CP-Zn sealers, respectively. A parallel biological evaluation at bacterial and cellular levels was per...
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#1Jinhui Huang (Sichuan University)H-Index: 2
#2Xue Xia (Sichuan University)H-Index: 1
Last. Yubao Li (Sichuan University)H-Index: 31
view all 8 authors...
Abstract A bi-solvent system (ethanol and water) with the presence of L-glutamic acid (L-glu) was developed to achieve the controlled synthesis of whisker-like or urchin-like Sr-substituted HA (SrHA) through hydrothermal treatment. The effects of initial temperature of aqueous solution (ASIT), the presence of Sr, and ethanol proportion on HA morphology were investigated and the underlying mechanisms were illustrated. The results indicate that Sr and ethanol have antagonistic effects on the size ...
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#1Miaomiao He (Sichuan University)H-Index: 3
#2Ce Zhu (Sichuan University)H-Index: 1
Last. Li Zhang (Sichuan University)H-Index: 32
view all 9 authors...
The use of polyetheretherketone (PEEK) has grown exponentially in the biomedical field in recent decades because of its outstanding biomechanical properties. However, its lack of bioactivity/osteointegration remains an unresolved issue toward its wide use in orthopedic applications. In this work, graphene nanosheets have been incorporated into PEEK to obtain multifunctional nanocomposites. Because of the formation of an electrical percolation network and the π-π* conjugation between graphene and...
1 CitationsSource
#1Chen Yuan (Sichuan University)
#2Xin Ren (Sichuan University)H-Index: 1
Last. Yubao Li (Sichuan University)H-Index: 31
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Mechanical and degradation properties are crucial factors of guided tissue/bone regeneration (GTR/GBR) membranes. In this work, a series of fibrous membranes with different ratios of polycaprolactone (PCL) and gelatin (Gel) were prepared (PCL:Gel = 1:9 (P1G9), 3:7 (P3G7), 5:5 (P5G5), 7:3 (P7G3), and 9:1 (P9G1)) by electrospinning, and their physicochemical properties and In Vitro degradation behaviors were systematically investigated. Mechanical tests showed that tensile strength was enhanced wi...
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#1Jinhui Huang (Sichuan University)H-Index: 2
#2Jiawei Wei (Sichuan University)H-Index: 1
Last. Yubao Li (Sichuan University)H-Index: 31
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Attributed to their structure and composition manipulated to mimic natural bone tissue, porous scaffolds composed of inorganic nano-hydroxyapatite (n-HA) and organic polymers with different degrees of degradability have been proven to be a promising bone regeneration strategy. However, long-term and in-depth comparative research on the effects of scaffolds with different matrices and degrees of degradability on bone reconstruction is still lacking. In this study, the ultralong-term osteogenic pe...
1 CitationsSource