G. Dréan
French Institute of Health and Medical Research
Internal medicineRadiologySurgeryOncologyArtificial intelligenceImage registrationPattern recognitionMedical physicsCross-validationPrincipal component analysisExternal beam radiotherapyProstateContext (language use)Prostate cancerRectumPlanned DosePopulationToxicityNuclear medicineRectal toxicityDose distributionSub regionComputer visionComputer scienceRadiation therapyVoxelMedicineCohortImage-guided radiation therapy
47Publications
8H-index
431Citations
Publications 34
Newest
#1Cedrik LafondH-Index: 7
#2J. N’GuessanH-Index: 1
Last. R. de CrevoisierH-Index: 20
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1 CitationsSource
#1A. Fargeas (French Institute of Health and Medical Research)H-Index: 5
#2Oscar Acosta (French Institute of Health and Medical Research)H-Index: 21
Last. R. de-Crevoisier (French Institute of Health and Medical Research)
view all 13 authors...
Objectif de l’etude Les objectifs etaient : de proposer un nouveau modele predictif de rectorragies apres radiotherapie pour cancer de la prostate base sur l’analyse en composantes independantes (ICA), utilisant a la fois l’information dosimetrique et non-dosimetrique (les caracteristiques specifiques aux patients, a la tumeur et au traitement). De comparer ce nouveau modele avec les modeles predictifs de la litterature utilisant ces memes informations : le Normal Tissue Complication Probability...
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#1G. Dréan (University of Rennes)H-Index: 8
#2Oscar Acosta (University of Rennes)H-Index: 21
Last. Renaud de Crevoisier (University of Rennes)H-Index: 28
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Abstract Background and purpose To identify rectal subregions at risks (SRR) highly predictive of 3-year rectal bleeding (RB) in prostate cancer IMRT. Materials and methods Overall, 173 prostate cancer patients treated with IMRT/IGRT were prospectively analyzed, divided into "training" ( n =118) and "validation" cohorts ( n =53). Dose–volume histograms (DVHs) were calculated in three types of rectal subregions: "geometric", intuitively defined (hemi-rectum,…); "personalized", obtained by non-rig...
32 CitationsSource
#1G. Dréan (University of Rennes)H-Index: 8
#2Oscar Acosta (University of Rennes)H-Index: 21
Last. Pascal Haigron (University of Rennes)H-Index: 21
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Purpose: Recent studies revealed a trend toward voxelwise population analysis in order to understand the local dose/toxicity relationships in prostate cancer radiotherapy. Such approaches require, however, an accurate interindividual mapping of the anatomies and 3D dose distributions toward a common coordinate system. This step is challenging due to the high interindividual variability. In this paper, the authors propose a method designed for interindividual nonrigid registration of the rectum a...
16 CitationsSource
Nov 5, 2015 in EMBC (International Conference of the IEEE Engineering in Medicine and Biology Society)
#1Juan David Ospina (University of Rennes)H-Index: 8
#2A. Fargeas (University of Rennes)H-Index: 5
Last. R De CrevoisierH-Index: 1
view all 6 authors...
In external beam radiotherapy for prostate cancer limiting toxicities for dose escalation are bladder and rectum toxicities. Normal tissue complication probability models aim at quantifying the risk of developping adverse events following radiotherapy. These models, originally proposed in the context of uniform irradiation, have evolved to implementations based on the state-of-the-art classification methods which are trained using empirical data. Recently, the use of image processing techniques ...
2 CitationsSource
#1L.H. Liu (University of Rennes)
#2Amar Kachenoura (University of Rennes)H-Index: 11
Last. Laurent Albera (University of Rennes)H-Index: 24
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Abstract External beam radiotherapy is one of the standard treatments for prostate cancer. Despite advanced radiotherapy techniques allowing precise dose delivery on cancer targets, efficiency of the treatment is limited by the risk of side-effects due to the irradiation to the surrounding organs. Characterizing the local dose–toxicity relationship is crucial to provide new recommendations for treatment planning. Standing on a voxel wise analysis, in this paper we proposed a new method, named Di...
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#1Julie Coloigner (French Institute of Health and Medical Research)H-Index: 7
#2A. Fargeas (French Institute of Health and Medical Research)H-Index: 5
Last. Laurent Albera (French Institute of Health and Medical Research)H-Index: 24
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The understanding of dose/side-effects relationships in prostate cancer radiotherapy is crucial to define appropriate individual's constraints for the therapy planning. Most of the existing methods to predict side-effects do not fully exploit the rich spatial information conveyed by the three-dimensional planned dose distributions. We propose a new classification method for three-dimensional individuals’ doses, based on a new semi-nonnegative ICA algorithm to identify patients at risk of present...
7 CitationsSource
#1G. DréanH-Index: 8
#2Oscar AcostaH-Index: 21
Last. R. de CrevoisierH-Index: 20
view all 9 authors...
Source
#1A. Fargeas (University of Rennes)H-Index: 5
#2Laurent Albera (University of Rennes)H-Index: 24
Last. Oscar Acosta (University of Rennes)H-Index: 21
view all 10 authors...
Abstract External beam radiotherapy is commonly prescribed for prostate cancer. Although new radiation techniques allow high doses to be delivered to the target, the surrounding healthy organs (rectum and bladder) may suffer from irradiation, which might produce undesirable side-effects. Hence, the understanding of the complex toxicity dose–volume effect relationships is crucial to adapt the treatment, thereby decreasing the risk of toxicity. In this paper, we introduce a novel method to classif...
9 CitationsSource
#1G. Dréan (University of Rennes)H-Index: 8
#2Oscar Acosta (University of Rennes)H-Index: 21
Last. R. de CrevoisierH-Index: 20
view all 9 authors...
Objectif En cas d’irradiation prostatique, les contraintes de dose portent sur le rectum en totalite. Il est probable qu’une sous-region rectale soit particulierement impliquee dans le risque de toxicite. L’objectif etait de caracteriser cette sous-region rectale. Patients et methodes Cent dix-huit patients ont recu une radiotherapie conformationnelle avec modulation d’intensite (RCMI) guidee par l’image pour un cancer de la prostate a la dose de 80 Gy. Trente et un ont souffert d’un evenement d...
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