J-Matthias Löhr
Karolinska University Hospital
EpidemiologyCancerMajor duodenal papillaSurgeryPathologyRetrospective cohort studyPancreatitisWarfarinExocrine pancreatic insufficiencyCachexiaAutoimmune pancreatitisPancreasDiseasePancreatic ductPancreatic cancerPancreatitis, chronicRisk factorDiabetes mellitusMedicineGastroenterology
30Publications
10H-index
371Citations
Publications 29
Newest
#1Maximilian Kordes (KI: Karolinska Institutet)H-Index: 2
#2Lars Larsson (KI: Karolinska Institutet)H-Index: 48
Last. J-Matthias Löhr (KI: Karolinska Institutet)H-Index: 10
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Cancer cachexia is a multifactorial syndrome that is characterised by a loss of skeletal muscle mass, is commonly associated with adipose tissue wasting and malaise, and responds poorly to therapeutic interventions. Although cachexia can affect patients who are severely ill with various malignant or non-malignant conditions, it is particularly common among patients with pancreatic cancer. Pancreatic cancer often leads to the development of cachexia through a combination of distinct factors, whic...
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#1J-Matthias Löhr (Karolinska University Hospital)H-Index: 10
#2Ulrich Beuers (UvA: University of Amsterdam)H-Index: 66
Last. Heiko Witt (TUM: Technische Universität München)H-Index: 40
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The overall objective of these guidelines is to provide evidence-based recommendations for the diagnosis and management of immunoglobulin G4 (IgG4)-related digestive disease in adults and children. IgG4-related digestive disease can be diagnosed only with a comprehensive work-up that includes histology, organ morphology at imaging, serology, search for other organ involvement, and response to glucocorticoid treatment. Indications for treatment are symptomatic patients with obstructive jaundice, ...
13 CitationsSource
#1K. J. Norberg (KI: Karolinska Institutet)H-Index: 1
#2Xinwang Liu (KI: Karolinska Institutet)H-Index: 24
Last. Johannes-Matthias Löhr (KI: Karolinska Institutet)H-Index: 11
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Pancreatic ductal adenocarcinoma is a devastating disease with poor outcome, generally characterized by an excessive stroma component. The purpose of this study was to develop a simple and reproducible in vitro 3D-assay employing the main constituents of pancreatic ductal adenocarcinoma, namely pancreatic stellate and cancer cells. A spheroid assay, directly co-culturing human pancreatic stellate cells with human pancreatic tumour cells in 3D was established and characterized by electron microsc...
7 CitationsSource
#1Ana Dugic (KI: Karolinska Institutet)H-Index: 1
#2Sara Nikolic (KI: Karolinska Institutet)H-Index: 1
Last. Miroslav Vujasinovic (Karolinska University Hospital)H-Index: 11
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Background: Except for pancreas divisum (PD), the prevalence of anatomic variants of the main pancreatic duct (MPD) seems to be insufficiently investigated. To date, their role in the occurrence of...
1 CitationsSource
#1Miroslav Vujasinovic (Karolinska University Hospital)H-Index: 11
#2Pia Maier (Karolinska University Hospital)H-Index: 1
Last. J-Matthias Löhr (KI: Karolinska Institutet)H-Index: 10
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BackgroundAutoimmune pancreatitis is a special form of chronic pancreatitis with strong lymphocytic infiltration and two histopathological distinct subtypes, a lymphoplasmacytic sclerosing pancreat...
1 CitationsSource
#1Sara Regnér (Lund University)H-Index: 23
#2J-Matthias Löhr (KI: Karolinska Institutet)H-Index: 10
: Patients with chronic pancreatitis have an impaired quality of life and are at risk for several long-term complications. It is important to diagnose and treat these patients to minimize the effects of the disease. Clinical manifestations of chronic pancreatitis include a wide range of symptoms and patients are managed differenth between medical centers. In recent years, there have been improvements in knowledge about treatment and management of patients with chronic pancreatitis. This is a sho...
#1Aleksandra Hedström (Karolinska University Hospital)H-Index: 4
#2Corinna Steiner (Karolinska University Hospital)H-Index: 1
Last. Miroslav Vujasinovic (Karolinska University Hospital)H-Index: 11
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INTRODUCTION: According to the European evidence-based consensus, published by European Crohn's and Colitis Organization (ECCO), diseases of the pancreas are included as extra-intestinal manifestations in IBD in the forms of acute pancreatitis (AP), chronic pancreatitis (CP), autoimmune pancreatitis (AIP), pancreatic duct abnormalities and pancreatic exocrine insufficiency (PEI). Presence of pancreatic autoantibodies directed against the exocrine of the pancreas has been reported in about one-th...
1 CitationsSource
#1Sara Nikolic (KI: Karolinska Institutet)H-Index: 1
#2Katharina Brehmer (Karolinska University Hospital)H-Index: 1
Last. Miroslav Vujasinovic (KI: Karolinska Institutet)H-Index: 1
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Introduction: Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated disease characterised pathologically by the infiltration of IgG4-bearing plasma cells into the involved organs. Autoimmune pancreatitis (AIP) is a form of chronic pancreatitis with a heavy lymphocytic infiltration and two distinct histopathological subtypes, namely: lymphoplasmacytic sclerosing pancreatitis (AIP type 1) and idiopathic duct-centric pancreatitis (AIP type 2). Lung involvement and aortic involve...
2 CitationsSource
#1Nikola PanicH-Index: 11
#1Nikola Panic (University of Belgrade)H-Index: 1
Last. J-Matthias Löhr (KI: Karolinska Institutet)H-Index: 10
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IntroductionAlthough pancreatic tuberculosis (TB) is traditionally considered to be a rare clinical entity, in recent times, an increase in the number of reports of pancreatic TB has been noted. We...
5 CitationsSource
#1Sara Nikolic (KI: Karolinska Institutet)H-Index: 1
#2Ana DugicH-Index: 1
Last. Miroslav Vujasinovic (KI: Karolinska Institutet)H-Index: 1
view all 7 authors...
BACKGROUND: It has been suggested that chronic pancreatitis (CP) may be an independent risk factor for development of cardiovascular disease (CVD). At the same time, it seems that congestive heart failure (CHF) and CP share the responsibility for the development of important clinical conditions such as sarcopenia, cachexia and malnutrition due to development of cardiac cachexia and pancreatic exocrine insufficiency (PEI), respectively. AIM: To explore the evidence regarding the association of CP...
1 CitationsSource