Tatsuya Atsumi
Hokkaido University
Internal medicineEndocrinologySurgeryPathologyAntibodyAutoantibodyRheumatologyImmunologyLupus erythematosusAntiphospholipid syndromeType 2 diabetesRheumatoid arthritisLupus anticoagulantThrombosisBeta 2-Glycoprotein IIn patientClinical trialDiabetes mellitusMedicineBiologyGastroenterology
561Publications
65H-index
14.4kCitations
Publications 556
Newest
#1Shuhei Shimoyama (Hokkaido University)H-Index: 1
#2Ikuma Nakagawa (Hokkaido University)H-Index: 6
Last. Masaaki Murakami (Hokkaido University)H-Index: 61
view all 16 authors...
Sjogren's syndrome (SS) is an autoimmune disease characterized by inflammation with lymphoid infiltration and destruction of the salivary glands. Although many genome-wide association studies have revealed disease-associated risk alleles, the functions of the majority of these alleles are unclear. Here, we show previously unrecognized roles of GTF2I molecules by using two SS-associated SNPs, rs73366469 and rs117026326 (GTF2I SNPs). We found that the risk alleles of GTF2I SNPs increased GTF2I exp...
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#1Tomonori Sekizaki (Hokkaido University)H-Index: 1
#2Hiraku Kameda (Hokkaido University)H-Index: 7
Last. Tatsuya Atsumi (Hokkaido University)H-Index: 65
view all 12 authors...
Dipeptidyl peptidase-4 (DPP-4), namely CD26, is expressed on the surface of immune cells, suggesting that inhibition of DPP-4 may affect the immune system. The current multicenter observational case-control study was conducted to investigate the effects of DPP-4 inhibitor (DPP-4i) administration on Graves' disease (GD) activity. This study comprised patients with GD and type 2 diabetes, who were administered an oral hypoglycemic agent (OHA) including DPP-4i. Exacerbation of GD was defined as an ...
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#1Keita Ninagawa (Hokkaido University)H-Index: 1
#2Masaru Kato (Hokkaido University)H-Index: 16
Last. Tatsuya Atsumi (Hokkaido University)H-Index: 65
view all 10 authors...
OBJECTIVES Systemic sclerosis associated pulmonary arterial hypertension (SSc-PAH) is of clinical significance owing to its poor outcome. One of the explanations for the outcome is the co-presence of left heart disease (LHD). The aim of this study is to assess LHD phenotype in patients with SSc and pulmonary hypertension (PH). METHODS This study included consecutive patients with SSc who underwent right heart catheterisation to diagnose PAH. Heart failure with preserved ejection fraction (HFpEF)...
#1Yuichiro Fujieda (Hokkaido University)H-Index: 15
#2Tetsuya HoritaH-Index: 23
Last. Tatsuya Atsumi (Hokkaido University)H-Index: 65
view all 24 authors...
No evidence has shown the efficacy of Sodium Risedronate (Risedronate) for glucocorticoid-induced osteoporosis (GIO) in patients with Rheumatoid arthritis (RA). The aim of this study was to explore...
1 CitationsSource
#1Hiroyuki Nakamura (Hokkaido University)H-Index: 10
#2Yuichiro Fujieda (Hokkaido University)H-Index: 15
Last. Tatsuya Atsumi (Hokkaido University)H-Index: 65
view all 4 authors...
Glucocorticoid-induced hyperglycemia (GIH) is an important complication to be managed by rheumatologists as it can affect morbidity and mortality of patients. Before administration of glucocorticoi...
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#1Tomonori Sekizaki (Hokkaido University)H-Index: 1
#2Hiraku Kameda (Hokkaido University)H-Index: 7
Last. Tatsuya Atsumi (Hokkaido University)H-Index: 65
view all 9 authors...
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#1Yuki Oe (Hokkaido University)
#2Hiraku Kameda (Hokkaido University)H-Index: 7
Last. Hideaki Miyoshi (Hokkaido University)H-Index: 16
view all 11 authors...
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#1Aika Miya (Hokkaido University)H-Index: 5
#2Akinobu Nakamura (Hokkaido University)H-Index: 20
Last. Tatsuya Atsumi (Hokkaido University)H-Index: 65
view all 9 authors...
AIMS/INTRODUCTION To identify the coefficient of variation (CV) threshold for unstable glucose variability (GV) and hypoglycemia, and to characterize a patient population with unstable GV and hypoglycemia. MATERIALS AND METHODS This was an observational study that enrolled 284 Japanese outpatients with type 2 diabetes who underwent continuous glucose monitoring. The C-peptide index (CPI = [(fasting serum C-peptide) / (plasma glucose)] × 100) was used as a marker of endogenous insulin secretion. ...
3 CitationsSource
#1Akiko YunoH-Index: 5
#2Yoshiyuki KenmotsuH-Index: 1
Last. Akira ShimatsuH-Index: 43
view all 19 authors...
We provide the details of the successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia. The patient was a 27-year-old Japanese female healthcare worker who was scheduled to undergo pituitary surgery for Cushing's disease. She had been in close contact with an undiagnosed patient infected with COVID-19 and then developed COVID-19 pneumonia. Despite a lack of known risk factors associated with severe COVID-19 infection, the pat...
2 CitationsSource
#1Aika Miya (Hokkaido University)H-Index: 5
#2Akinobu Nakamura (Hokkaido University)H-Index: 20
Last. Tatsuya Atsumi (Hokkaido University)H-Index: 65
view all 10 authors...
The contribution of endogenous insulin secretion to glycemic variability (GV) may differ between patients with impaired insulin secretion and those with preserved secretion. Our objective was to determine the linearity of the relationship between fasting C-peptide (CPR) as a marker of endogenous insulin secretion and GV in type 2 diabetes (T2DM), regardless of the type of antidiabetic treatment. We conducted a prospective observational study using continuous glucose monitoring obtained from 284 ...
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