Yoo Li Lim
Yonsei University
CD90Internal medicineEndocrinologyBalloonSurgeryPathologyOncologyOdds ratioResectionHepatic stellate cellAdverse effectMesenchymal stem cellClinical endpointHazard ratioPositron emission tomographyBiopsyHepatitisSurvival rateHepatitis CTenosynovitisTendon sheathAdenoviridaeCombination therapyIschemic colitisLiver diseaseCirrhosisHepatitis BHematopoietic stem cell transplantationMelenaAlcoholic liver diseaseEsophageal varicesLiver biopsyVaricesHepatocellular carcinomaPropranololCutoffInternational Prognostic IndexDecompensationPortal hypertensionEndoscopic mucosal resectionRifaximinChronic liver diseaseLymphomaApelinB symptomsDecorinAbdomenForeign bodyBone marrowCreatinineProthrombin timeAscitesFibrosisPolypectomyLeptinAlcoholic hepatitisDifferential diagnosisAbdominal painSMADPopulationAnal vergeLiver stiffnessRas InhibitorTransplantationArea under the roc curveLiver functionHepatic fibrosisComplete resectionTumor sizeSingle surgeonIn patientNon invasiveAnatomical resectionHepatologyAnesthesiaConfidence intervalDoubling timeCancer researchLiver function testsPortal venous pressureReceiver operating characteristicEndoglinMedicineAnastomosisBiologyGastroenterologyMeta-analysis
13Publications
7H-index
189Citations
Publications 13
Newest
#1Yoo Li Lim (Yonsei University)H-Index: 7
#2Young Woo Eom (Yonsei University)H-Index: 17
Last. Moon Young Kim (Yonsei University)H-Index: 32
view all 8 authors...
Background and objectives Autologous or allogeneic bone marrow-derived mesenchymal stem cells (BMSCs) have been applied in clinical trials to treat liver disease. However, only a few studies are comparing the characteristics of autologous MSCs from patients and allogeneic MSCs from normal subjects. Methods and results We compared the characteristics of BMSCs (BCs and BPs, respectively) isolated from six healthy volunteers and six patients with cirrhosis. In passage 3 (P3), senescent population a...
1 CitationsSource
#1Min Sun Park (Yonsei University)H-Index: 1
#2Soonchang Hong (Yonsei University)H-Index: 9
Last. Moon Young Kim (Yonsei University)H-Index: 32
view all 6 authors...
Background/Aims: Acute hepatic dysfunction combined with alcoholic hepatitis (AH) in alcoholic cirrhosis is related to hepatic hypo-perfusion secondary to intrahepatic necroinflammation, neoangiogenesis, and shunt. The hepatic vein arrival time (HVAT) assessed by microbubble contrast-enhanced ultrasonography (CEUS) is closely correlated with the severity of intrahepatic changes. We investigated the usefulness of HVAT to predict short-term mortality of AH in cirrhosis. Methods: Thirty-nine patien...
4 CitationsSource
#1Yoo Li Lim (Yonsei University)H-Index: 7
#2Moon Young Kim (Yonsei University)H-Index: 32
Last. Sang Ok Kwon (Yonsei University)H-Index: 25
view all 5 authors...
Background/Aims: Non-selective beta blockers (NSBBs) are currently the only accepted regimen for preventing portal hypertension (PHT)-related complications. However, the effect of NSBBs is insufficient in many cases. Bacterial translocation (BT) is one of the aggravating factors of PHT in cirrhosis; therefore, selective intestinal decontamination by rifaximin is a possible therapeutic option for improving PHT. We investigated whether the addition of rifaximin to propranolol therapy can improve h...
13 CitationsSource
#1Yoon Ok Jang (Yonsei University)H-Index: 10
#2Mee Yon Cho (Yonsei University)H-Index: 20
Last. Sang Ok Kwon (Yonsei University)H-Index: 25
view all 10 authors...
Abstract : Bone marrow-derived mesenchymal stem cells (BM-MSCs) are known to have an antifibrotic effect and could be used as vehicles for targeted gene delivery. Decorin plays a protective role against fibrogenesis by modulating the degradation of the extracellular matrix. The aim of this study was to determine whether the antifibrotic effect of a combination treatment consisting of BM-MSCs and decorin on hepatic fibrosis is superior to BM-MSCs alone. The effects of BM-MSCs infected with decori...
26 CitationsSource
#1Chang Jo Im (Yonsei University)
#2Ji Hoon Na (Yonsei University)
Last. Hee Man Kim (Yonsei University)H-Index: 22
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Most ingested foreign bodies pass readily throughout intestinal tract if they reach the stomach. In some cases, foreign bodies may be impacted behind a luminal constriction but are rare in colon. Here, we report the case of a 59-year-old man who did laparoscopic anterior resection due to sigmoid colon cancer 2 years ago and ischemic colitis was repeated on the anastomosis site. He initially presented with symptoms of abdominal pain 3 months before and melena 1 day before admission. Abdomen compu...
Source
#1Hyun Soo Kim (Yonsei University)H-Index: 51
#2H Jung (Yonsei University)H-Index: 4
Last. Mee Yon ChoH-Index: 20
view all 9 authors...
Source
#1Gaeun Kim (KMU: Keimyung University)H-Index: 14
#2Juyoung Kim (KMU: Keimyung University)H-Index: 1
Last. Soon Koo Baik (Yonsei University)H-Index: 42
view all 5 authors...
Background and aims The renin–angiotensin system (RAS) has an important role in hepatic fibrosis and portal hypertension. RAS inhibitors are already accepted in clinical fields for antihypertensive management, but their effects on hepatic fibrosis are controversial. The aim of this study was to systematically review the effects of RAS inhibitors on hepatic fibrosis based on histological assessment.
28 CitationsSource
#1Yoo Li Lim (Yonsei University)H-Index: 7
#2Eunhee Choi (Yonsei University)H-Index: 27
Last. Moon Young Kim (Yonsei University)H-Index: 32
view all 8 authors...
Levels of serum apelin (s-apelin), an endogenous ligand for angiotensin-like receptor 1, have been shown to be related to hepatic fibrosis and hemodynamic abnormalities in preclinical studies. We investigated the clinical implications of s-apelin as a noninvasive prognostic biomarker for chronic liver disease (CLD).From January 2009 to December 2012, 215 CLD patients were enrolled and underwent clinical data collection, hepatic venous pressure gradient (HVPG) measurement, and liver biopsy. s-ape...
22 CitationsSource
#2Yoo Li LimH-Index: 7
#3Sunghoon KimH-Index: 13
Last. Soon Koo BaikH-Index: 4
view all 4 authors...
Aims: The positivity of stemness markers in hepatocellular carcinoma (HCC) has been reported to have a correlation with aggressive tumor factors and poor survival. Additionally, the effectiveness of anatomical resection is still debate. We analyzed the effectiveness of anatomical resection in patients with HCC in aspect of CD 133 expression. Methods: We retrospectively reviewed the medical records of 94 patients who underwent liver resection from Mar. 2012 to Oct. 2015 by single surgeon. We inve...
#1Gaeun Kim (KMU: Keimyung University)H-Index: 14
#2Young Woo Eom (Yonsei University)H-Index: 17
Last. Sei Jin Chang (Yonsei University)H-Index: 26
view all 8 authors...
Based on their ability to differentiate into multiple cell types including hepatocytes, the transplantation of mesenchymal stem cells (MSCs) has been suggested as an effective therapy for chronic liver diseases. The aim of this study was to evaluate the safety, efficacy and therapeutic effects of MSCs in patients with chronic liver disease through a literature-based examination. We performed a systematic review (SR) and meta-analysis (MA) of the literature using the Ovid-MEDLINE, EMBASE and Coch...
38 CitationsSource