Michael Larsen
Copenhagen University Hospital
OphthalmologyInternal medicineSurgeryCohort studyMacular degenerationFundus photographyRetinaVisual acuityRetinopathyOptical coherence tomographyDiabetic retinopathyFluorescein angiographyRetinalRanibizumabPopulationDiabetes mellitusMedicineBiology
486Publications
62H-index
9,447Citations
Publications 453
Newest
#1Christina Eckmann-Hansen (Glostrup Hospital)H-Index: 1
#2Mathias Hvidtfelt Hansen (Glostrup Hospital)
Last. Michael Larsen (Glostrup Hospital)H-Index: 62
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PURPOSE To examine cone density in relation to gestational and morphological parameters in the Copenhagen Child Cohort (CCC2000). METHODS The macula was imaged using adaptive optics in 1,296 adolescents aged 16-17 years. Axial length and distance visual acuity were determined. Absolute and angular cone photoreceptor density were analysed for an 80 × 80-pixel area, 2 degrees temporal to the fovea. Association with axial length was analysed with linear regression. Correlation with visual acuity wa...
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#1Jakob Bjerager (Glostrup Hospital)
#2Sami Dabbah (Glostrup Hospital)
Last. Michael Larsen (Glostrup Hospital)H-Index: 62
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Lens and skin fluorescence are related to the systemic accumulation of advanced glycation end products, which is accelerated in diabetes. We have examined lens fluorescence and skin fluorescence in healthy adult twins. The study enrolled twins aged median 59 years from a national population-based registry. Diabetic individuals were excluded from analysis. The interrelatedness between fluorescence parameters and relations between fluorescence and age, current HbA1c and smoking pack years were exa...
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#1Bente Mertz Nørgård (University of Southern Denmark)H-Index: 29
#2Mette Wod (University of Southern Denmark)H-Index: 7
Last. Jens Fedder (University of Southern Denmark)H-Index: 28
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Objective null To examine whether medications used to treat rheumatoid arthritis (RA)/chronic inflammatory bowel disease (IBD), or factors related to the assisted reproductive technology (ART) procedures, impact the success of ART. In women with RA/IBD, initial studies have shown a reduced chance of a live-born child after ART. null null null Design null Cohort study. null null null Setting null Nationwide Danish health registries. null null null Patients null All Danish women with a fresh embry...
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#1Abdullah Amini (UCPH: University of Copenhagen)H-Index: 1
#2Daniel El Fassi (Herlev Hospital)
Last. Anne Willerslev (Glostrup Hospital)H-Index: 3
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#1Michael Patrick Achiam (Copenhagen University Hospital)H-Index: 15
#2Marianne Nordsmark (Aarhus University Hospital)H-Index: 32
Last. S Dikinis (AAU: Aalborg University)
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Background null Decisions regarding tumor staging, operability, resectability, and treatment strategy in patients with esophageal cancer are made at multidisciplinary team (MDT) conferences. We aimed to assess interobserver agreement from four national MDT conferences and whether this would have a clinical impact. null Methods null A total of 20 patients with esophageal cancer were included across all four upper gastrointestinal (GI) cancer centers. Fully anonymized patient data were distributed...
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#1Sofie BeierH-Index: 4
Last. Michael Larsen (UCPH: University of Copenhagen)H-Index: 62
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Abstract Low vision readers depend on magnification, but magnification reduces the amount of text that can be overviewed and hampers text navigation. In this study, we evaluate the effects that font variations letter spacing, letter width, and letter boldness have on low vision reading. We tested 20 low-vision patients with age-related macular degeneration (AMD) and used the Radner Reading Chart, which measures reading acuity (logRAD), maximum reading speed, and critical print size. The results ...
1 CitationsSource
#1Mohamed Belmouhand (Copenhagen University Hospital)H-Index: 2
#2Christina Eckmann-Hansen (Copenhagen University Hospital)H-Index: 1
Last. Michael Larsen (Copenhagen University Hospital)H-Index: 62
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BACKGROUND Deferoxamine retinopathy is the informally designated term used to describe a characteristic pattern of outer retinal degeneration in iron-overloaded chronic anemia patients who are treated with deferoxamine. We hypothesize that insufficiently treated iron overloading and not only deferoxamine is the cause of the retinal degeneration. Our case report is based on exposure histories of two anemia patients and literature review. CASE PRESENTATION Both anemia patients presented with bilat...
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#1Jean-François Korobelnik (French Institute of Health and Medical Research)H-Index: 39
#2Michael Larsen (UCPH: University of Copenhagen)H-Index: 62
Last. Varun Chaudhary (St. Joseph's Healthcare Hamilton)H-Index: 9
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PURPOSE To evaluate the efficacy and safety of intravitreal aflibercept (IVT-AFL) treat-and-extend (TE P<0.0001 [test against threshold of 40%]) of patients gained ≥15 letters; and, during the TE P=0.8822 [test against threshold of 50%]) of patients achieved a mean treatment interval ≥8 wks. A last and next planned treatment interval of ≥8 wks was achieved by 63.1% (n=101) and 67.5% (n=108) of patients, respectively. Mean (standard deviation) best-corrected visual acuity increased from 51.9 (16....
3 CitationsSource
#1Bente Mertz Nørgård (University of Southern Denmark)H-Index: 29
#2Laura Catalini (University of Southern Denmark)
Last. Jens Fedder (University of Southern Denmark)H-Index: 28
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Assisted reproductive technology (ART) treatments in women with underlying chronic diseases have become increasingly frequent. The objective of this review is to provide an overview of the literature examining the chance of having a live born child after ART in women with chronic diseases, compared to other women receiving ART. We focused on some of the most prevalent chronic diseases in women during their reproductive years, ie ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple...
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#1Xavier Benoit D’Journo (AMU: Aix-Marseille University)H-Index: 26
#2David Boulate (AMU: Aix-Marseille University)H-Index: 1
Last. J. Jan B. van Lanschot (EUR: Erasmus University Rotterdam)H-Index: 25
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Importance null Ninety-day mortality rates after esophagectomy are an indicator of the quality of surgical oncologic management. Accurate risk prediction based on large data sets may aid patients and surgeons in making informed decisions. null Objective null To develop and validate a risk prediction model of death within 90 days after esophagectomy for cancer using the International Esodata Study Group (IESG) database, the largest existing prospective, multicenter cohort reporting standardized p...
1 CitationsSource