Donald J. Hagler
Mayo Clinic
AnatomyInternal medicineRadiologySurgeryMagnetic resonance imagingPsychologyCardiologyNeuroscienceCognitionHemodynamicsCardiac catheterizationVentricleHeart diseasePercutaneousPulmonary arteryTemporal lobeWhite matterBrain mappingMagnetoencephalographyMedicineBiology
455Publications
88H-index
20.5kCitations
Publications 449
Newest
#1William R. Miranda (Mayo Clinic)H-Index: 14
#2C. Charles Jain (Mayo Clinic)H-Index: 4
Last. Donald J. Hagler (Mayo Clinic)H-Index: 88
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Abstract Although the arterial switch operation has become the standard form of surgical repair for complete transposition of the great arteries, a large number of adults post-atrial switch are still followed in current practice. Pulmonary venous baffle obstruction is a well-known complication of the atrial switch operation, mimicking heart failure. Its recognition is important as it is a potentially treatable disease. In the past, retrograde pulmonary venous atrium (PVA)/pulmonary venous baffle...
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#1Talha Niaz (Mayo Clinic)H-Index: 8
#2Jonathan N. Johnson (Mayo Clinic)H-Index: 30
Last. Donald J. Hagler (Mayo Clinic)H-Index: 88
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Abstract null null Objective null To elucidate sex differences in valve morphology, disease phenotype, progression, and outcomes among children and young adults with bicuspid aortic valve (BAV). null null null Patients and Methods null This is a retrospective cohort study examining all children and young adults (aged ≤22 years) with isolated BAV diagnosed, by excluding patients with concomitant congenital heart defects or genetic syndromes, from January 1, 1990, through December 1, 2016, at Mayo...
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#1Chun Chieh Fan (UCSD: University of California, San Diego)H-Index: 26
#2R. J. Loughnan (UCSD: University of California, San Diego)H-Index: 4
Last. Anders M. Dale (UCSD: University of California, San Diego)H-Index: 166
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It is important to understand the molecular determinants for microstructures of human brain. However, past genome-wide association studies (GWAS) on microstructures of human brain have had limited results due to methodological constraints. Here, we adopt advanced imaging processing methods and multivariate GWAS on two large scale imaging genetic datasets (UK Biobank and Adolescent Brain Cognitive Development study) to identify and validate key genetic association signals. We discovered 503 uniqu...
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#1Marybel Robledo Gonzalez (UCSD: University of California, San Diego)H-Index: 4
#2William F.C. Baaré (Copenhagen University Hospital)H-Index: 32
Last. Kathrine Skak Madsen (Copenhagen University Hospital)H-Index: 10
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Abstract null null Verbal fluency is the ability to retrieve lexical knowledge quickly and efficiently and develops during childhood and adolescence. Few studies have investigated associations between verbal fluency performance and brain structural variation in children. Here we examined associations of verbal fluency performance with structural measures of frontal and temporal language-related brain regions and their connections in 73 typically-developing children aged 7–13 years. Tract-based s...
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#1Bader Chaarani (UVM: University of Vermont)H-Index: 12
#2Sage Hahn (UVM: University of Vermont)H-Index: 2
Last. Matthew D. Albaugh (UVM: University of Vermont)H-Index: 21
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The Adolescent Brain Cognitive Development (ABCD) Study® is a 10-year longitudinal study of children recruited at ages 9 and 10. A battery of neuroimaging tasks are administered biennially to track neurodevelopment and identify individual differences in brain function. This study reports activation patterns from functional MRI (fMRI) tasks completed at baseline, which were designed to measure cognitive impulse control with a stop signal task (SST; N = 5,547), reward anticipation and receipt with...
2 CitationsSource
#1Clare E. Palmer (University of California, Berkeley)H-Index: 11
#2Diliana Pecheva (UCSD: University of California, San Diego)H-Index: 5
Last. Anders M. DaleH-Index: 166
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During late childhood behavioral changes, such as increased risk-taking and emotional reactivity, have been associated with the maturation of cortico-subcortical circuits. null Understanding microstructural changes in subcortical regions may aid our understanding of how individual differences in these behaviors emerge. null Restriction spectrum imaging (RSI) is a framework for modelling diffusion-weighted imaging that decomposes the diffusion signal from a voxel into hindered and restricted comp...
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#1Clare E. Palmer (University of California, Berkeley)H-Index: 11
#2Diliana Pecheva (UCSD: University of California, San Diego)H-Index: 5
Last. Anders M. DaleH-Index: 166
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Development in late childhood has been associated with microstructural changes in white matter (WM) that are hypothesized to underpin concurrent changes in cognitive and behavioral function. Restriction spectrum imaging (RSI) is a framework for modelling diffusion-weighted imaging that can probe microstructural changes within hindered and restricted compartments providing greater specificity than diffusion tensor imaging for characterizing intracellular diffusion. Using RSI, we modelled voxelwis...
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#1Michael V. Lombardo (IIT: Istituto Italiano di Tecnologia)H-Index: 56
#2Lisa T. Eyler (UCSD: University of California, San Diego)H-Index: 47
Last. Eric Courchesne (UCSD: University of California, San Diego)H-Index: 116
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Cortical regionalization develops via genomic patterning along anterior-posterior (A-P) and dorsal-ventral (D-V) gradients. Here we find that normative A-P and D-V genomic patterning of cortical surface area (SA) and thickness (CT) present in typically developing and autistic toddlers with good early language outcome, is absent in autistic toddlers with poor early language outcome. Autistic toddlers with poor early language outcome are instead specifically characterized by secondary and independ...
1 CitationsSource
#1Michael V. Lombardo (IIT: Istituto Italiano di Tecnologia)H-Index: 56
#2Lisa T. Eyler (UCSD: University of California, San Diego)H-Index: 47
Last. Natasha Bertelsen (IIT: Istituto Italiano di Tecnologia)H-Index: 1
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Cortical regionalization develops via genomic patterning along anterior-posterior (A-P) and dorsal-ventral (D-V) gradients. Here we find that normative A-P and D-V genomic patterning of cortical surface area (SA) and thickness (CT) present in typically developing and autistic toddlers with good early language outcome, is absent in autistic toddlers with poor early language outcome. Autistic toddlers with poor early language outcome are instead specifically characterized by secondary and independ...
1 CitationsSource
#1Yi Li (UCSF: University of California, San Francisco)H-Index: 94
#2Wesley K. Thompson (UCSD: University of California, San Diego)H-Index: 68
Last. Sandra A. Brown (UCSD: University of California, San Diego)H-Index: 124
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Importance Incidental findings (IFs) are unexpected abnormalities discovered during imaging and can range from normal anatomic variants to findings requiring urgent medical intervention. In the case of brain magnetic resonance imaging (MRI), reliable data about the prevalence and significance of IFs in the general population are limited, making it difficult to anticipate, communicate, and manage these findings. Objectives To determine the overall prevalence of IFs in brain MRI in the nonclinical...
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