Huayu Yang
Capital Medical University
Matrix metalloproteinaseInternal medicineEndocrinologyPathologyOncologyGene expressionRenal functionStage (cooking)LipocalinAlbuminuriaWestern blotValsartanKidney diseaseStreptozotocinOverdiagnosisDiabetic nephropathyKidneyIntraperitoneal injectionPrognostic factorNephrologyDiabetes mellitusMedicineUrinary system
Publications 3
#1Huayu Yang (Capital Medical University)H-Index: 2
#2Haiping Chen (Capital Medical University)H-Index: 3
Last. Qing Ma (Capital Medical University)H-Index: 5
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BACKGROUND Matrix metalloproteinases-9 (MMP-9) can regulate extracellular matrix deposition in diabetic glomerular injury. However, it remains unknown whether MMP-9 is involved in the renal tubular injury. Meanwhile, neutrophil gelatinase-associated lipocalin (NGAL), defined as a biomarker of proximal tubular injury, may influence MMP-9 by forming the MMP-9/NGAL complex. The aim of this study was to investigate MMP-9 expression in proximal renal tubules and the relationship of MMP-9 and NGAL in ...
#1Fenghua Liu (Capital Medical University)H-Index: 1
#2Huayu Yang (Capital Medical University)H-Index: 2
Last. Qing Ma (Capital Medical University)H-Index: 5
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Abstract Purpose Recent evidence suggests that neutrophil gelatinase-associated lipocalin (NGAL) plays important roles in many physiological and pathological processes including diabetic nephropathy (DN), in which a markedly increasing in NGAL levels in patient's serum and urine has been reported. This study investigated the expression of NGAL in the kidney of diabetic rats. Materials/methods Sixty-four Sprague Dawley rats were randomly divided into 2 groups: non-diabetic control groups and diab...
15 CitationsSource
#1Conghui Liu (Capital Medical University)H-Index: 1
#2Haiping Chen (Capital Medical University)H-Index: 3
Last. Qing Ma (Capital Medical University)H-Index: 5
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Background Estimated glomerular filtration rate (eGFR) is the sole diagnostic criterion for stage 3a chronic kidney disease (CKD). Because eGFR decreases with age, its prognostic utility in the elderly is controversial. Albuminuria is an important prognostic factor. To confirm that eGFR use may lead to the overdiagnosis of CKD and to examine the utility of eGFR combined with albuminuria for diagnosing stage 3a CKD in the elderly.
4 CitationsSource