Limei Yu
Zunyi Medical College
EndocrinologyPathologyCellGene expressionMolecular biologyAndrologyFetusChemistryMesenchymal stem cellVascular smooth muscleStem cellPopulationTransplantationCancer researchFlow cytometryCell growthMedicineEvolutionary biologyBiologyCell biology
Publications 37
#1Wan XueH-Index: 1
#2Linyan Li (Zunyi Medical College)
Last. Limei Yu (Zunyi Medical College)H-Index: 12
view all 5 authors...
BACKGROUND Recurrent spontaneous abortion (RSA) is often idiopathic, but structural chromosomal abnormality is an important nosogenesis. Balanced translocations or inversions can lead to unbalanced gametes depending on the specific recombination and segregation patterns during meiosis. An unbalanced karyotype in the conceptus of a couple when one partner has a structural chromosomal abnormality may result in failure to implant, miscarriage, or ongoing pregnancy of a fetus with an unbalanced kary...
#1Kuang Wei (Zunyi Medical College)H-Index: 1
#2Tao Liu (Zunyi Medical College)H-Index: 2
Last. Changyin Yu (Zunyi Medical College)H-Index: 3
view all 6 authors...
#1Kuang Wei (Zunyi Medical College)H-Index: 1
#2Tao Liu (Zunyi Medical College)H-Index: 2
Last. Changyin Yu (Zunyi Medical College)H-Index: 3
view all 6 authors...
The purpose of this study is to observe the effect of icariside II (ICS II) on the differentiation of human amniotic mesenchymal stem cells (hAMSCs) into dopaminergic neuron-like cells, the involvement of PI3K signaling pathway inhibitors. After identifying hAMSCs by flow cytometry, hAMSCs were induced and treated with ICS II at 10 μmol/L, 3 μmol/L, 1 μmol/L, and 0 μmol/L. hAMSCs in the LY294002+3μM ICS II group were pretreated with 20 μmol/L LY294002, a PI3K-specific inhibitor, for 1 h, and the...
#1Anling Hu (CAS: Chinese Academy of Sciences)H-Index: 1
#1An-Ling HuH-Index: 3
Last. Shang-Fu Xu (Zunyi Medical College)H-Index: 7
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Abstract Ethnopharmacological relevance Panax ginseng C. A. Mey. is a traditional tonic that has been used for thousands of years, and has positive effects on vascular diseases. Ginsenoside Rg1 (GS-Rg1) is one of the active ingredients of Panax ginseng C. A. Mey., and has been shown to have beneficial effects against ischemia/reperfusion injury. Our previously study has found that GS-Rg1 can mobilize bone marrow stem cells and inhibit vascular smooth muscle proliferation and phenotype transforma...
2 CitationsSource
#1Li LuoH-Index: 3
#2Hongyan GaoH-Index: 4
Last. Pengyu ChenH-Index: 11
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BACKGROUND X-chromosome short tandem repeats (X-STRs) with unique sex-linkage inheritance models play a complementary role in forensic science. Guizhou is a multiethnic province located in southwest China and some genetic evidence focusing on X-STRs for various minorities was reported. However, population data of Guizhou Tujia are scarce. METHODS A total of 507 Guizhou Tujia individuals were profiled using the AGCU X-19 STR kit. Allele frequencies and forensic parameters were calculated. Additio...
#1Rui YangH-Index: 2
#2Hongfei GaoH-Index: 1
Last. Tao Zhang
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Introduction Mesenchymal stem cells (MSCs) have always been the center of the experimental exploration of regenerative therapy together with other stem cells. Among with, peripheral blood-derived mesenchymal stem cells (PBMSCs) have been regarded as promising in clinical applications for its convenience of acquisition from peripheral blood. However, few reported experiments so far to elucidate the exact mechanisms of how PBMSC influence regeneration. As the ability of immunomodulatory is one of ...
3 CitationsSource
#1Fang HeH-Index: 1
#2Wang YuyingH-Index: 3
Last. Limei YuH-Index: 12
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Abstract Aims To investigate the therapeutic effects of human amniotic mesenchymal stem cells (hAMSCs) on paraquat (PQ)-induced pulmonary fibrosis in rats and investigate the inflammatory mechanisms. Main methods hAMSCs were identified by morphological, flow cytometry and immunocytochemistry. A pulmonary fibrosis model was induced by administering PQ to rats. The hAMSC group was treated with hAMSCs after 6 h of PQ poisoning. At 21 days after hAMSC transplantation, lungs were harvested for H&E, M...
6 CitationsSource
#1Zhong-Yuan ZhangH-Index: 1
#2Jin YangH-Index: 1
Last. Chang-Yin YuH-Index: 1
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Suture and autologous nerve transplantation are the primary therapeutic measures for completely severed nerves. However, imbalances in the microenvironment and adhesion of surrounding tissues can affect the quality of nerve regeneration and repair. Previous studies have shown that human amniotic membrane can promote the healing of a variety of tissues. In this study, the right common peroneal nerve underwent a 5-mm transection in rats. Epineural nerve repair was performed using 10/0 non-absorbab...
4 CitationsSource
#1Pengyu ChenH-Index: 11
#2Jian WuH-Index: 2
Last. Guanglin HeH-Index: 13
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Modern East Asians derived from the admixture of aborigines and incoming farmers expanding from Yellow and Yangtze River Basins. Distinct genetic differentiation and subsequent admixture between Northeast Asians and Southeast Asians subsequently evidenced by the mitochondrial DNA, Y-chromosomal variations, and autosomal SNPs. Recently, population geneticists have paid more attention to the genetic polymorphisms and background of southern-Han Chinese and southern native populations. The genetic l...
11 CitationsSource
#1Rongxia LiuH-Index: 1
#2Xiaoyu ZhangH-Index: 1
Last. Limei Yu (Zunyi Medical College)H-Index: 12
view all 9 authors...
Many adult women younger than 40 years old have premature ovarian failure (POF) and infertility. Previous studies confirmed that different tissue-derived stem cells could restore ovarian function and folliculogenesis in chemotherapy-induced POF mice. The aim of this study was to explore the therapeutic efficacy and underlying mechanisms of human amniotic mesenchymal stem cells (hAMSCs) transplantation for hydrogen peroxide-induced ovarian damage. Bilateral ovaries of female mice were burned with...
15 CitationsSource