Eugène van Puijenbroek
University of Groningen
PharmacyInternal medicineOdds ratioIntensive care medicinePediatricsProspective cohort studyAdverse effectCohort studyAlternative medicinePharmacoepidemiologyPregnancyMEDLINEDrugAdverse drug reactionDrug reactionHealth professionalsAnesthesiaFamily medicineMedical emergencyPharmacovigilanceMedicinePharmacology
Publications 194
#1Naomi T. JessurunH-Index: 5
#2Marjolein Drent (UM: Maastricht University)H-Index: 65
Last. Aalt Bast (UM: Maastricht University)H-Index: 91
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Simvastatin has previously been associated with drug-induced interstitial lung disease. In this retrospective observational study, cases with non-specific interstitial pneumonia (NSIP) or idiopathic pulmonary fibrosis (IPF) with simvastatin-associated pulmonary toxicity (n = 34) were evaluated. To identify whether variations in genes encoding cytochrome P450 (CYP) enzymes or in the SLCO1B1 gene (Solute Carrier Organic anion transporting polypeptide 1B1 gene, encoding the organic anion transporti...
#1Nanno Schreuder (UG: University of Groningen)H-Index: 2
#2Iris de Romijn (UU: Utrecht University)
Last. Eugène van Puijenbroek (UG: University of Groningen)H-Index: 25
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Patients with chronic kidney disease (CKD) may need to have their radiopharmaceutical dosage adjusted to prevent adverse effects and poor outcomes, but there are few recommendations on radiopharmaceutical dosing for this group of patients. The aim of this study is to provide an overview of the available information on radiopharmaceutical dose recommendations for patients with CKD. We performed a systematic literature review according to the Preferred Reporting Items for Systematic Reviews and Me...
Patient-reported outcomes (PROs) on adverse drug reactions (ADRs) are increasingly used in cohort event monitoring (CEM) to obtain a better understanding of patients’ real-world experience with dru...
#1Agnes KantH-Index: 5
#2Florence van HunselH-Index: 15
Last. Eugène van Puijenbroek (UG: University of Groningen)H-Index: 25
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Due to the high intensity of the COVID-19 vaccination campaigns and heightened attention for safety issues, the number of spontaneous reports has surged. In the Netherlands, pharmacovigilance centre Lareb has received more than 100 000 reports on adverse events following immunization (AEFI) associated with Covid-19 vaccination. It is tempting to interpret absolute numbers of reports of AEFIs in signal detection. Signal detection of spontaneously reported adverse drug reactions has its origin in ...
#1Naomi T. Jessurun (UG: University of Groningen)H-Index: 5
#2Hieronymus J. Derijks (Radboud University Nijmegen)H-Index: 3
Last. Koen GrootensH-Index: 1
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The antipsychotic drug clozapine is associated with weight gain. The proposed mechanisms include blocking of serotonin (5-HT2a/2c ), dopamine (D2 ) and histamine (H1 ) receptors. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2) to norclozapine, a metabolite with more 5-HT2c -receptor and less H1 blocking capacity. We hypothesized that norclozapine serum levels correlate with body mass index (BMI), waist circumference and other parameters of the metabolic syndrome. We performed a retrospe...
#1Tanja FensH-Index: 2
#2Denise Hope (Griffith University)H-Index: 5
Last. Katja TaxisH-Index: 24
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The utilization of serious games and simulations in health professional education has increased. The Pharmacy Game is one such concept that intersects gamification and simulation, in which pharmacy student teams competitively manage simulated pharmacies; a concept included in the pharmacy curricula of seven international universities. This study aimed to compare the implementation and conduct of the Pharmacy Game of participant universities and their students’ performance in the same educational...
#1L. F. Perez-Garcia (EUR: Erasmus University Rotterdam)H-Index: 2
#2Radboud J E M Dolhain (EUR: Erasmus University Rotterdam)H-Index: 28
Last. Martijn B.A. van Doorn (EUR: Erasmus University Rotterdam)H-Index: 12
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Abstract Introduction Information about the possible effects of cutaneous immune-mediated diseases (cIMDs) on male sexual function and reproduction is scarce. Factors known to impair sexual health and reproduction, such as inflammation, medication use, and hypogonadism, can be present in a significant proportion of male patients with cIMD. Objectives To systematically review the literature for the influence of paternal cIMD on many aspects of male sexual and reproductive health, such as sexual f...
#1Hardjit Kharagjitsing (Albert Schweitzer Hospital)
#2Rike van Eekeren (UG: University of Groningen)H-Index: 5
Last. Eric F.H. van Bommel (Albert Schweitzer Hospital)H-Index: 12
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Aims Retroperitoneal fibrosis (RPF) is a rare chronic fibro-inflammatory disorder that may be secondary to certain drugs, including β-blocking agents (BBAs). However, their causative role is unclear. We aimed to investigate this association. Methods Disproportionality analysis was carried out on cases from 1985 to 4 October 2020 in VigiBase, the World Health Organization pharmacovigilance database. The Bayesian-based IC025 metric and reporting odds ratio were used in order to assess the adverse ...
OBJECTIVE We aimed to describe the nature and frequency of gastrointestinal adverse drug reactions (GI-ADRs) of etanercept (ETN) using patient-reported and healthcare professional (HCP)-registered data and compared this frequency with the GI-ADR frequency of the widely used TNFα-inhibitor adalimumab. METHODS Reported GI-ADRs of ETN for rheumatic diseases were collected from the Dutch Biologic Monitor and DREAM registries. We described the clinical course of GI-ADRs and compared the frequency wit...
#1Tanja FensH-Index: 2
#3Maarten J. PostmaH-Index: 71