Subhash C. Chauhan
University of Texas at Austin
PhysicsCancerInternal medicinePathologyChemistryApoptosisImmunologyOrmeloxifeneCervical cancerCurcuminMetastasisDrug deliveryProstate cancerPancreatic cancerCell cycleCancer researchCell growthMedicineBiologyCancer cellPharmacology
277Publications
49H-index
6,392Citations
Publications 255
Newest
#1Subhash C. ChauhanH-Index: 49
Last. Amar Kant GautamH-Index: 6
view all 6 authors...
Source
#1Mohammed Sikander (University of Texas at Austin)H-Index: 7
#1Mohammed Sikander (University of Texas at Austin)
Last. Meena Jaggi (University of Texas at Austin)H-Index: 36
view all 9 authors...
COVID-19 is known as one of the deadliest pandemics of the century. The rapid spread of this deadly virus at incredible speed has stunned the planet and poses a challenge to global scientific and medical communities. Patients with COVID-19 are at an increased risk of co-morbidities associated with liver dysfunction and injury. Moreover, hepatotoxicity induced by antiviral therapy is gaining importance and is an area of great concern. Currently, alternatives therapies are being sought to mitigate...
1 CitationsSource
#1Elham Hatami (UTHSC: University of Tennessee Health Science Center)H-Index: 6
#2Prashanth K.B. Nagesh (UTHSC: University of Tennessee Health Science Center)H-Index: 10
Last. Murali M. Yallapu (University of Texas at Austin)H-Index: 34
view all 5 authors...
Abstract Non-small cell lung cancer (NSCLC) is the most frequent type of lung cancer accounting up to 80–85% of all lung cancer (LC) cases. Gemcitabine (Gem), a pyrimidine nucleoside antimetabolite, is widely used chemotherapy offering several months survival benefit in patients with NSCLC. The emergence of Gem resistance is a main clinical concern in cancer treatment and thus a continuous demand for development of new therapeutic strategies to improve its antitumor activity. Hence, we report an...
2 CitationsSource
#1Vivek K. Kashyap (University of Texas at Austin)H-Index: 8
#2Anupam Dhasmana (University of Texas at Austin)H-Index: 7
Last. Meena Jaggi (University of Texas at Austin)H-Index: 1
view all 5 authors...
Source
#1Deepak S. ChauhanH-Index: 10
#2Rajendra Prasad (IITB: Indian Institute of Technology Bombay)H-Index: 9
Last. Murali M. YallapuH-Index: 34
view all 6 authors...
COVID-19 has dramatically challenged the healthcare system of almost all countries. The authorities are struggling to minimize the mortality along with ameliorating the economy downturn. Unfortunately, till now, there has been no promising medicine or vaccine available. Herein, we deliver a perspective of nanotechnology for increasing the specificity and sensitivity of current interventional platforms towards the urgent need of quickly deployable solutions. This review summarizes the recent invo...
18 CitationsSource
#1Vivek K. KashyapH-Index: 8
#2Anupam Dhasmana (University of Texas at Austin)H-Index: 7
Last. Subhash C. Chauhan (The University of Texas Rio Grande Valley)H-Index: 5
view all 8 authors...
The coronavirus disease 2019 (COVID-19) pandemic, an infection caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2), has led to more than 771,000 deaths worldwide. Tobacco smoking is a major known risk factor for severe illness and even death from many respiratory infections. The effects of smoking on COVID-19 are currently controversial. Here, we provide an overview of the current knowledge on the effects of smoking on the clinical manifestations, disease progression, inflam...
7 CitationsSource
#1Neeraj Chauhan (University of Texas at Austin)H-Index: 8
#1Neeraj Chauhan (University of Texas at Austin)H-Index: 24
Last. Murali M. YallapuH-Index: 34
view all 5 authors...
microRNAs (miRNAs) are a class of small non-coding RNAs that regulate the expression of their target mRNAs post transcriptionally. miRNAs are known to regulate not just a gene but the whole gene network (signaling pathways). Accumulating evidence(s) suggests that miRNAs can work either as oncogenes or tumor suppressors, but some miRNAs have a dual nature since they can act as both. miRNA 205 (miR-205) is one such highly conserved miRNA that can act as both, oncomiRNA and tumor suppressor. Howeve...
4 CitationsSource
#1Anupam Dhasmana (The University of Texas Rio Grande Valley)H-Index: 1
#2Vivek Kumar Kashyap (The University of Texas Rio Grande Valley)H-Index: 1
Last. Subhash C. Chauhan (The University of Texas Rio Grande Valley)H-Index: 49
view all 9 authors...
Previously human society has faced various unprecedented pandemics in the history and viruses have majorly held the responsibilities of those outbreaks. Furthermore, due to amplified global connection and speedy modernization, epidemic outbreaks caused by novel and re­emergingviruses signify potential risk to community health. Despite, great advancements in immunization and drug discovery processes, still various viruses lack prophylactic vaccines and efficient antiviral therapies. Although, vac...
1 CitationsSource
#1Kyle Doxtater (UTHSC: University of Tennessee Health Science Center)H-Index: 3
#2Chidi Zacheaus (UTHSC: University of Tennessee Health Science Center)H-Index: 2
Last. Manish K. TripathiH-Index: 13
view all 14 authors...
Background: Colorectal carcinoma (CRC) is the second leading cause of cancer related deaths in the United States. The five-year survival rate of patients diagnosed with distant stages declines to 14%, which is of concern when compared to 90% for localized-stage and 71% for regional stage disease. This necessitates the need for early diagnostic biomarkers, to minimize poor drug response/resistance, recurrence, metastasis and mortality. Disproportionate biochemical stressors increase the risk of d...
Source
#1Sonam KumariH-Index: 8
#2Sheema Khan (The University of Texas Rio Grande Valley)
Last. Meena Jaggi (The University of Texas Rio Grande Valley)H-Index: 1
view all 6 authors...
Background Pancreatic cancer is one of the deadliest malignancies, and fourth leading cause of cancer-related deaths in the United States. Aberrant glucose metabolism in cancer cells leads to enhanced tumor growth and aggressiveness. Herein, we have identified an important constituent, steviol from the plant Stevia rebaudiana, which inhibits pancreatic cancer cells via modulation of glucose metabolism and protein translation. Methods Glucose and Lactate assays were performed in pancreatic cancer...
Source