Toshihiro Koyama
Okayama University
PharmacyHistamineVasodilationInternal medicineEndocrinologyPublic healthDemographyOdds ratioAdrenergicCalcitonin gene-related peptideRetrospective cohort studyMortality rateChemistryMedical prescriptionGuanethidineEndotheliumVasoconstrictionMethoxamineMesenteric arteriesPopulationAnesthesiaIncidence (epidemiology)Confidence intervalAntibioticsMedicinePharmacology
60Publications
13H-index
457Citations
Publications 60
Newest
#1Koichi Keitoku (U.H.: University of Hawaii at Manoa)
#2Yoshito Nishimura (U.H.: University of Hawaii at Manoa)
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 5 authors...
OBJECTIVES To evaluate the impact of the World Antimicrobial Awareness Week (WAAW) on public awareness of antimicrobial resistance using Google Trends analysis. METHODS The impact of WAAW on public awareness of 'antimicrobial resistance' (AMR), 'antibacterial', and 'antibiotics' in Japan, the UK, the United States, and worldwide from 2015 to 2020 was analyzed, using the relative search volume (RSV) of Google Trends as a surrogate. A joinpoint regression analysis was performed to identify a stati...
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#1Krixie Silangcruz (U.H.: University of Hawaii at Manoa)
#2Yoshito Nishimura (U.H.: University of Hawaii at Manoa)
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 7 authors...
Abstract null Background null More than 6 million people are affected by inflammatory bowel disease (IBD) globally. World IBD Day (WID; May 19) and Crohn’s and Colitis Awareness Week (CCAW; December 1–7) occur yearly as national health observances to raise public awareness of IBD, but their effects are unclear. null Methods null This study evaluates the impact of WID and CCAW on the public awareness of IBD in the United States (US) and worldwide from 2016 to 2020 using the relative search volume...
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#1Ko Harada (Okayama University)H-Index: 3
#2Hideharu Hagiya (Okayama University)H-Index: 13
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 6 authors...
BACKGROUND The incidence of nontuberculous mycobacterial (NTM) infections has been increasing worldwide, becoming a significant healthcare burden especially among elderly people. This study aimed to evaluate the trends in NTM-associated mortality in Japan. METHODS This study used vital statistics data and data on all NTM-associated deaths (N=18,814) among individuals aged ≥40 years in Japan from 1997 to 2016. We calculated the crude and age-adjusted mortality rates by age and sex and used joinpo...
1 CitationsSource
#1Jun Matsumoto (Okayama University)H-Index: 5
#2Yumi Kotera (Okayama University)
Last. Noritaka Ariyoshi (Okayama University)H-Index: 29
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BACKGROUND/AIM This study aimed to elucidate the detailed characteristics of CYP3A5 expression and the association between CYP3A5 expression and clinical outcomes in patients with renal cell carcinoma (RCC). PATIENTS AND METHODS This study retrospectively enrolled 124 Japanese patients with RCC treated at the Okayama University Hospital. The commonest CYP3A5 gene polymorphism, CYP3A5*3, and expression levels of CYP3A5 mRNA and protein in each tissue were examined. RESULTS Expression of CYP3A5 mR...
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#1Hideharu Hagiya (Okayama University)H-Index: 13
#2Toshihiro Koyama (Okayama University)H-Index: 13
Last. Mitsunobu R. Kano (Okayama University)H-Index: 35
view all 13 authors...
BACKGROUND AND AIM The current prevalence of hepatitis C virus infection and hepatitis C virus-associated mortality in Japan falls short of the World Health Organization goal of viral hepatitis elimination by 2030. We aimed to evaluate the trends in hepatitis C virus-associated mortality in Japan. METHODS This nationwide observational study used the Japanese Vital Statistics from 1998 to 2017 and included all Japanese hepatitis C virus-associated deaths (84,936) of adults aged ≥40 years. We calc...
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#3Hideharu Hagiya (Okayama University)H-Index: 13
Adverse drug events (ADEs) are a major cause of mortality. We examined long-term trends for ADE-related deaths in Japan. This observational study was conducted using the Japanese Vital Statistics from 1999 to 2016. Data for all ADE-related deaths were extracted using International Classification of Diseases, Tenth Revision codes. We analysed ADE-related deaths by age and sex and calculated crude and age-standardised mortality rates (ASMR) per 100,000 people. We used Joinpoint regression analysis...
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#1Shinnosuke Fukushima (Okayama University)
#2Hideharu Hagiya (Okayama University)H-Index: 13
Last. Fumio Otsuka (Okayama University)H-Index: 35
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This study examined temporal trend, seasonality, and geographical variations of legionellosis incidence and mortality in Japan. This nationwide observational study used the Japanese Vital Statistics and Infectious Diseases Weekly Report (1999-2017) data to calculate legionellosis crude and age-adjusted incidence and mortality rates per 100,000 population by age and sex. Incidence was compared among the 4 seasons and regional incidence among 47 prefectures. Of 13,613 (11,194 men) people with legi...
1 CitationsSource
#1Yoshito Nishimura (Okayama University)H-Index: 5
#2Ko Harada (Okayama University)H-Index: 3
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 5 authors...
In the era of hyper-ageing, Creutzfeldt-Jakob disease (CJD) can become more prevalent as an important cause of dementia. This study aimed to evaluate the trends in crude and age-adjusted CJD-associated mortality and incidence rates in Japan using national vital statistics data on CJD-associated deaths among individuals aged over 50 years, as well as the government-funded nationwide CJD surveillance data (pertaining to the years 2005-2014) in Japan. The data were analysed using the Joinpoint Regr...
2 CitationsSource
#1Toshihiro Koyama (Okayama University)H-Index: 13
#2Hideharu Hagiya (Osaka University)H-Index: 13
Last. Mitsunobu R. KanoH-Index: 35
view all 15 authors...
Abstract Objectives Appropriate antibiotic prescriptions for outpatients with acute respiratory tract infections (ARTIs) are urgently needed in Japan. However, the empirical proof of this need is under-documented. Therefore, we aimed to determine antibiotic prescription rates, and the proportions of antibiotic classes prescribed for Japanese patients with ARTIs. Methods We analysed health insurance claims data over 2013–2015 among Japanese patients aged Results Among 8.65 million visits due to A...
3 CitationsSource
#1Toshihiro Koyama (Okayama University)H-Index: 13
#2Hideharu Hagiya (Okayama University)H-Index: 13
Last. Mitsunobu R. Kano (UTokyo: University of Tokyo)H-Index: 35
view all 13 authors...
Background: Globally, the number of deaths is estimated to increase to 74 million per year by 2030. Place of death (PoD) is increasingly being recognized as an important aspect of end-of-life care....
1 CitationsSource