Ralph L. Sacco
University of Miami
EpidemiologyInternal medicineSurgeryDemographyOdds ratioCardiologyPhysical therapyProspective cohort studyCohort studyHazard ratioVascular diseaseDiseasePopulationIschemic strokeRisk factorStrokeDiabetes mellitusMedicineCohortGerontology
Publications 1012
#1Larry B. GoldsteinH-Index: 95
#2Sudha SeshadriH-Index: 114
Last. Ralph L. SaccoH-Index: 157
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#1Martin BretznerH-Index: 3
#2Anna K BonkhoffH-Index: 3
Last. Marco NardinH-Index: 4
view all 56 authors...
#1Sungmin Hong (Harvard University)H-Index: 4
#2Anne-Katrin Giese (UHH: University of Hamburg)H-Index: 1
Last. Kathleen L. Donahue (Harvard University)H-Index: 4
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Objective: To personalize the prognostication of post-stroke outcome using MRI-detected cerebrovascular pathology, we sought to investigate the association between the excessive white matter hyperintensity (WMH) burden unaccounted for by the traditional stroke risk profile of individual patients and their long-term functional outcomes after a stroke. Methods: We included 890 patients who survived after an acute ischemic stroke from the MRI-Genetics Interface Exploration (MRI-GENIE) study, for wh...
#1Negar Asdaghi (UM: University of Miami)H-Index: 18
#2Jose G. Romano (UM: University of Miami)H-Index: 25
Last. Eric E. Smith (U of C: University of Calgary)H-Index: 102
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Background and Purpose: Mild ischemic stroke patients enrolled in randomized controlled trials of thrombolysis may have a different symptom severity distribution than those treated in routine clini...
#1Emily M. Briceño (UM: University of Michigan)H-Index: 14
#2Alden L. Gross (Johns Hopkins University)H-Index: 35
Last. Clinton B. Wright (NIH: National Institutes of Health)H-Index: 59
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BACKGROUND Meta-analyses of individuals' cognitive data are increasing to investigate the biomedical, lifestyle, and sociocultural factors that influence cognitive decline and dementia risk. Pre-statistical harmonization of cognitive instruments is a critical methodological step for accurate cognitive data harmonization, yet specific approaches for this process are unclear. OBJECTIVE To describe pre-statistical harmonization of cognitive instruments for an individual-level meta-analysis in the b...
#1Gillian L. Gordon Perue (UM: University of Miami)H-Index: 1
#2Susan E. Fox-Rosellini (UM: University of Miami)
Last. Heidi Allespach (UM: University of Miami)H-Index: 1
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Racial inequities as illustrated by the health disparities in COVID19 infections and deaths, the recent killings of Black men and women by law enforcement, and the widening socioeconomic inequality and have brought systemic racism into a national conversation. These unprecedented times may have deleterious consequences, increasing stress, and trauma for many members of the neurology workforce. The Equity, Diversity, Inclusion and Anti-Racism Committee within our Department of Neurology provides ...
1 CitationsSource
Abstract null null Background null Intracranial atherosclerotic stenosis (ICAS) is one of the most common causes of stroke worldwide and confers a high risk of stroke recurrence, despite aggressive management of risk factors. null null null Objectives null This study identified the role of risk factors and risk of vascular events in subjects with asymptomatic ICAS for improved risk stratification. null null null Methods null Stroke-free participants in the NOMAS (Northern Manhattan Study) trial,...
1 CitationsSource
#1Nina A. Hilkens (UU: Utrecht University)H-Index: 6
#2Ale Algra (UU: Utrecht University)H-Index: 98
Last. Jean-Louis Mas (Paris V: Paris Descartes University)H-Index: 72
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Background and Purpose: Lifelong treatment with antiplatelet drugs is recommended following a transient ischemic attack or ischemic stroke. Bleeding complications may offset the benefit of antiplat...
#1Mitchell S.V. Elkind (Columbia University)H-Index: 91
#2Michelle P. Moon (Columbia University)
Last. Mady Hornig (Columbia University)H-Index: 50
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Abstract null null Objective null To determine whether immune protein panels add significant information to correlates of cognition. null null null Background null Immune mechanisms in vascular cognitive aging are incompletely characterized. null null null Design/methods null A subsample of the prospective Northern Manhattan Study underwent detailed neuropsychological testing. Cognitive scores were converted into Z-scores and categorized into four domains (memory, language, processing speed, and...
#1Kenji Matsumoto (Columbia University)H-Index: 3
#2Zhezhen Jin (Columbia University)H-Index: 50
Last. Marco R. Di Tullio (Columbia University)H-Index: 55
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Hypertension is the most prevalent modifiable risk factor for stroke. Office blood pressure (BP) measurements may have limitations in defining the impact of hypertension on stroke. Our aim was to compare the stroke risk for office, central, and ambulatory BP measurements in a predominantly older population-based prospective cohort. Participants in the CABL study (Cardiovascular Abnormalities and Brain Lesions; n=816; mean age, 70.8±9.0 years; 39.8% men) underwent applanation tonometry of the rad...