Michael J. Young
Massachusetts Eye and Ear Infirmary
OphthalmologyNeural stem cellPathologyCellular differentiationChemistryGlial cell line-derived neurotrophic factorProgenitor cellImmunologyRetinaNestinRetinalRetinal degenerationRecoverinStem cellTransplantationTissue engineeringMedicineBiologyCell biology
170Publications
43H-index
6,008Citations
Publications 160
Newest
#1Michael J. Young (Harvard University)H-Index: 43
#2Brian L. Edlow (Harvard University)H-Index: 25
Growing awareness of shortcomings of standard behavioral approaches to the diagnosis and prognosis of patients with disorders of consciousness (DoC) has paved the way for neurotechnological discove...
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#1Michael J. Young (Harvard University)H-Index: 43
#2Rachel A Caplan (Harvard University)
Last. Farrah J. Mateen (Harvard University)H-Index: 29
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#1Michael J. Young (Harvard University)H-Index: 43
#2Brian L. Edlow (Harvard University)H-Index: 25
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#1Caleb R. S. McEntire (Harvard University)
#2Kun-Wei Song (Harvard University)
Last. Farrah J. Mateen (Harvard University)H-Index: 29
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The World Health Organization (WHO) monitors the spread of diseases globally and maintains a list of twenty diseases with epidemic or pandemic potential: Chikungunya, cholera, Crimean-Congo hemorrhagic fever, ebola virus disease, Hendra virus infection, influenza, Lassa fever, Marburg virus disease, Neisseria meningitis, MERS-CoV, monkeypox, Nipah virus infection, novel coronavirus (2019-nCoV), plague, Rift Valley fever, SARS, smallpox, tularemia, yellow fever, and Zika virus disease. These path...
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#1Robert W. Regenhardt (Harvard University)H-Index: 15
#2Michael J. Young (Harvard University)H-Index: 43
Last. Thabele M Leslie-Mazwi (Harvard University)H-Index: 25
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The coronavirus disease 2019 (COVID-19) pandemic has had widespread effects across healthcare systems worldwide.1–3 Mounting evidence supports a relationship between COVID-19 and both stroke pathophysiology4 5 and stroke systems of care, with decreased stroke presentations and delays in care.6 7 The pandemic’s effects have been felt at the patient level where fears of contagion may foster avoidance of the hospital environment,8 at the provider level where working conditions have been strained, a...
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#1Leonard L. Sokol (NU: Northwestern University)H-Index: 4
#2Joshua Hauser (NU: Northwestern University)H-Index: 13
Last. Michael J. Young (Harvard University)H-Index: 43
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: Stroke is a leading cause of disability and mortality worldwide. Recent advances in stroke care now enable patients with severe ischemic stroke owing to large vessel occlusion to safely undergo endovascular thrombectomy (EVT) up to 24 hours since their time of last known well, with the goal of improving functional outcomes by recanalization of the occluded vessel and reperfusion of downstream ischemic brain tissue. The objective of this analysis is to highlight clinical and ethical challenges ...
1 CitationsSource
#1Pierre C. Dromel (MIT: Massachusetts Institute of Technology)H-Index: 1
#2Deepti SinghH-Index: 14
Last. Michael J. YoungH-Index: 43
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#1Alicia Arranz-Romera (Complutense University of Madrid)H-Index: 4
#2Maria Hernandez (University of Navarra)H-Index: 7
Last. Irene Bravo-Osuna (Complutense University of Madrid)H-Index: 19
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We assessed the sustained delivery effect of poly (lactic-co-glycolic) acid (PLGA)/vitamin E (VitE) microspheres (MSs) loaded with glial cell-derived neurotrophic factor (GDNF) alone (GDNF-MSs) or combined with brain-derived neurotrophic factor (BDNF; GDNF/BDNF-MSs) on migration of the human adult retinal pigment epithelial cell-line-19 (ARPE-19) cells, primate choroidal endothelial (RF/6A) cells, and the survival of isolated mouse retinal ganglion cells (RGCs). The morphology of the MSs, partic...
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#1Deepti Singh (Harvard University)H-Index: 14
#2Pierre C. Dromel (MIT: Massachusetts Institute of Technology)H-Index: 1
Last. Michael J. Young (Harvard University)H-Index: 43
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The optic pathway glioma (OPG) is a slow-growing brain tumor that arises along the optic nerve or its downstream connections and causing vision to gradually worsen with time. This tumor forms in ch...
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#1Robert W. Regenhardt (Harvard University)H-Index: 15
#2Michael J. Young (Harvard University)H-Index: 43
Last. Thabele M Leslie-Mazwi (Harvard University)H-Index: 25
view all 10 authors...
Background Persons with pre-existing disabilities represent over one-third of acute stroke presentations, but account for a far smaller proportion of those receiving endovascular thrombectomy (EVT) and thrombolysis. This is despite existing ethical, economic, legal, and social directives to maximize equity for this vulnerable population. We sought to determine associations between baseline modified Rankin Scale (mRS) and outcomes after EVT. Methods Individuals who underwent EVT were identified f...
2 CitationsSource