Gill Levitt
Great Ormond Street Hospital
CancerInternal medicineSurgeryPathologyOncologyHealth carePediatricsAdverse effectYoung adultWilms' tumorChemotherapyAnthracyclineDiseaseMEDLINEGuidelinePopulationChildhood cancerRadiation therapyFamily medicineMedicine
Publications 87
#1Edit Bardi (Boston Children's Hospital)H-Index: 1
#2Renée L. MulderH-Index: 17
Last. Daniel M. Green (St. Jude Children's Research Hospital)H-Index: 57
view all 19 authors...
Abstract null null Background null Survivors of childhood, adolescent and young adult (CAYA) cancer may develop treatment-induced chronic liver disease. Surveillance guidelines can improve survivors’ health outcomes. However, current recommendations vary, leading to uncertainty about optimal screening. The International Late Effects of Childhood Cancer Guideline Harmonization Group has developed recommendations for the surveillance of late hepatotoxicity after CAYA cancer. null null null Methods...
#1Elvira C. van DalenH-Index: 28
#2Renée L. MulderH-Index: 17
Last. Eva Frey (Boston Children's Hospital)H-Index: 11
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BACKGROUND Coronary artery disease (CAD) is a concerning late outcome for cancer survivors. However, uniform surveillance guidelines are lacking. AIM To harmonise international recommendations for CAD surveillance for survivors of childhood, adolescent and young adult (CAYA) cancers. METHODS A systematic literature review was performed and evidence graded using the Grading of Recommendations, Assessment, Development and Evaluation criteria. Eligibility included English language studies, a minimu...
#1Julianne ByrneH-Index: 20
#2Irene Schmidtmann (University of Mainz)H-Index: 25
Last. Eva Frey (Boston Children's Hospital)H-Index: 11
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Late mortality of European five-year survivors of childhood or adolescent cancer has dropped over the last 60 years, but excess mortality persists. There is little information concerning secular trends in cause-specific mortality among older European survivors. PanCareSurFup pooled data from 12 cancer registries and clinics in 11 European countries from 77 423 five-year survivors of cancer diagnosed before age 21 between 1940 to 2008 followed for an average age of 21 years and a total of 1.27 mi...
Last. Riccardo Haupt (Istituto Giannina Gaslini)H-Index: 44
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Abstract null null Background null Long-term follow-up (LTFU) care for childhood, adolescent, and young adult (CAYA) cancer survivors is essential to preserve health and quality of life (QoL). Evidence-based guidelines are needed to inform optimal surveillance strategies, but many topics are yet to be addressed by the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG). Therefore, the PanCareFollowUp Recommendations Working Group collaborated with stakeholders to ...
#1Anne Lotte Lolkje Femke van der Kooi (Erasmus University Medical Center)H-Index: 1
#2Renée L. MulderH-Index: 17
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ABSTRACT Objective Female childhood, adolescent, and young adult (CAYA) cancer survivors have an increased risk of adverse pregnancy outcomes related to their cancer or treatment-associated sequelae. Optimal care for CAYA cancer survivors can be facilitated by clinical practice guidelines that identify specific adverse pregnancy outcomes and the clinical characteristics of at-risk subgroups. However, national guidelines are scarce and vary in content. Here, the International Late Effects of Chil...
2 CitationsSource
#2Elvira C. van DalenH-Index: 28
Last. Leontien C M KremerH-Index: 7
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Objective: In this report, we determine the cumulative incidence of symptomatic cardiac ischaemia and its risk factors among European 5-year childhood cancer survivors (CCS) participating in the PanCareSurFup study. Methods: Eight data providers (France, Hungary, Italy (two cohorts), the Netherlands, Slovenia, Switzerland and the UK) participating in PanCareSurFup ascertained and validated symptomatic cardiac events among their 36 205 eligible CCS. Data on symptomatic cardiac ischaemia were grad...
5 CitationsSource
#1Renée L. MulderH-Index: 17
#2Melissa M. Hudson (St. Jude Children's Research Hospital)H-Index: 104
Last. Kevin C. Oeffinger (Duke University)H-Index: 87
view all 18 authors...
PURPOSEAs new evidence is available, the International Late Effects of Childhood Cancer Guideline Harmonization Group has updated breast cancer surveillance recommendations for female survivors of ...
9 CitationsSource
#1Gisela Michel (University of Lucerne)H-Index: 29
#2Renée L. MulderH-Index: 17
Last. Gill Levitt (Great Ormond Street Hospital for Children NHS Foundation Trust)H-Index: 35
view all 11 authors...
Purpose To facilitate the implementation of long-term follow-up (LTFU) care and improve equality of care for childhood, adolescent, and young adult (CAYA) cancer survivors, the PanCareSurFup Guidelines Working Group developed evidence-based recommendations for the organization of LTFU.
26 CitationsSource
#1Julianne ByrneH-Index: 20
#2Daniela Alessi (CEU: Cancer Epidemiology Unit)H-Index: 11
Last. Lars Hjorth (Lund University)H-Index: 24
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Background: Second malignant neoplasms and cardiotoxicity are among the most serious and frequent adverse health outcomes experienced by childhood and adolescent cancer survivors (CCSs) and contribute significantly to their increased risk of premature mortality. Owing to differences in health-care systems, language and culture across the continent, Europe has had limited success in establishing multi-country collaborations needed to assemble the numbers of survivors required to clarify the healt...
14 CitationsSource
#1Riccardo Haupt (Istituto Giannina Gaslini)H-Index: 44
#2Samira EssiafH-Index: 6
Last. Janine Vetsch (University of Lucerne)H-Index: 13
view all 40 authors...
Background: Currently, there are between 300,000 and 500,000 childhood cancer survivors (CCSs) in Europe. A significant proportion is at high risk, and at least 60% of them develop adverse health-related outcomes that can appear several years after treatment completion. Many survivors are unaware of their personal risk, and there seems to be a general lack of information among healthcare providers about pathophysiology and natural history of treatment-related complications. This can generate inc...
32 CitationsSource