Chiara Costa
University of Messina
CancerInternal medicineRadiologyEndocrinologyPathologyPesticideKinaseChemistryImmunologyOxidative stressParaoxonaseAntioxidantProstate cancerPopulationToxicityEnvironmental exposureOccupational exposureFood scienceReactive oxygen speciesCancer researchAsbestosBiochemistryBioinformaticsMedicineBiomarker (medicine)BiologyImmune systemPharmacology
64Publications
23H-index
1,322Citations
Publications 71
Newest
#1Giusi Briguglio (UNIME: University of Messina)H-Index: 8
#2Chiara Costa (UNIME: University of Messina)H-Index: 23
Last. Concettina Fenga (UNIME: University of Messina)H-Index: 26
view all 6 authors...
Source
#1Federica Giambò (UCSC: Catholic University of the Sacred Heart)H-Index: 1
#2Gian Marco Leone (University of Catania)H-Index: 2
Last. Concettina Fenga (UNIME: University of Messina)H-Index: 26
view all 0 authors...
Environmental or occupational exposure to pesticides is considered one of the main risk factors for the development of various diseases. Behind the development of pesticide-associated pathologies, there are both genetic and epigenetic alterations, where these latter are mainly represented by the alteration in the expression levels of microRNAs and by the change in the methylation status of the DNA. At present, no studies have comprehensively evaluated the genetic and epigenetic alterations induc...
Source
#1Chiara Costa (UNIME: University of Messina)H-Index: 23
#2Manuela Pollicino (UNIME: University of Messina)H-Index: 3
Last. Concettina Fenga (UNIME: University of Messina)H-Index: 26
view all 0 authors...
Background: null null null Work ability consists in the balance between employee’s capabilities and work demands. It can be measured by the Work Ability Index, a validated questionnaire that has been used in Europe since 1980s. This study is the first evaluating work ability among dock workers, a workforce which carries out complex activities requiring physical and mental engagement (night shifts, irregular shifts, constant demand for attention and concentration and significant physical effort)....
Source
#1Chiara Costa (UNIME: University of Messina)H-Index: 23
#2Michele Teodoro (UNIME: University of Messina)H-Index: 8
Last. Concettina Fenga (UNIME: University of Messina)H-Index: 26
view all 9 authors...
Since the novel coronavirus (SARS-CoV-2) has spread worldwide, healthcare workers-resident physicians in particular-have been hugely involved in facing the COVID-19 pandemic, experiencing unprecedented challenges in fighting the disease. We aimed to evaluate the prevalence of poor sleep quality, daytime sleepiness, and alterations in mood state profiles in this category. This cross-sectional study, conducted in 2020, enrolled 119 subjects from a university hospital in southern Italy. Epworth Sle...
Source
In recent years, new targets have been included between the health outcomes induced by pesticide exposure. The gastrointestinal tract is a key physical and biological barrier and it represents a primary site of exposure to toxic agents. Recently, the intestinal microbiota has emerged as a notable factor regulating pesticides’ toxicity. However, the specific mechanisms related to this interaction are not well known. In this review, we discuss the influence of pesticide exposure on the gut microbi...
Source
#1Chiara CostaH-Index: 23
#2Giusi BriguglioH-Index: 8
Last. Concettina FengaH-Index: 26
view all 9 authors...
Stressful life events, are differently handled by women and men. This study evaluates gender differences in perceived stress and health status among a sample of subjects going through a transition period from unemployment to work. This cross-sectional study enrolled 395 participants, 245 men (62%) and 150 (38%) women, between 19 and 67 years, that were going to be hired for a 6-month contract. Before being employed, all participants underwent a mandatory protocol consisting in a general medical ...
Source
Work organization, such as shifts and night work, can interfere with the perception of work-related stress and therefore on the development of pathological conditions. Night shift work, particularly, can have a negative impact on workers' wellbeing by interfering with the biological sphere. The aim of this study is to evaluate the associations between work activities, shift work effects and stress-related responses in 106 dock workers enrolled in southeast Italy. Dock workers' tasks consist of c...
Source
#1Federica Giambò (UNIME: University of Messina)H-Index: 5
#2Sebastiano Italia (UNIME: University of Messina)H-Index: 2
Last. Concettina Fenga (UNIME: University of Messina)H-Index: 26
view all 8 authors...
Source
#1Concettina Fenga (UNIME: University of Messina)H-Index: 26
#2Briguglio Giusi (UNIME: University of Messina)
Last. Chiara Costa (UNIME: University of Messina)H-Index: 23
view all 3 authors...
Abstract null null There is a growing public health concern regarding the possibility that occupational and environmental exposure to pesticides can cause transient and permanent changes in the immune system resulting in the onset of serious disorders such as neurodegenerative inflammatory bowel disease, cancer, rheumatoid arthritis, and other inflammatory disorders, as well as conditions related to metabolic syndrome, through the activation of oxidative stress. Nonetheless, most studies on huma...
Source
#1Giusi Briguglio (UNIME: University of Messina)H-Index: 8
#2Chiara Costa (UNIME: University of Messina)H-Index: 23
Last. Concettina Fenga (UNIME: University of Messina)H-Index: 26
view all 6 authors...
Source
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