Sanjun Cai
Fudan University
Survival analysisEpidemiologyCancerInternal medicineRadiologySurgeryOncologyRetrospective cohort studyStage (cooking)MetastasisLymph nodeNomogramMultivariate analysisCancer researchProportional hazards modelRadiation therapyColorectal cancerMedicineBiologyGastroenterology
Publications 248
#1Guo X Cai (Fudan University)
#2Ming-Yan Cai (Fudan University)H-Index: 21
Last. Ping-Hong Zhou (Fudan University)H-Index: 32
view all 6 authors...
#1X. Guan (Southern Medical University)
#2S. Cai (Southern Medical University)
Last. Y. Chen (Southern Medical University)
view all 8 authors...
#7Lei Shen (Fudan University)H-Index: 26
#1Yaqi Wang (Fudan University)H-Index: 4
#2Lifeng Yang (Fudan University)H-Index: 6
Last. Xue WuH-Index: 21
view all 19 authors...
BACKGROUND For locally advanced rectal cancer (LARC) patients who receive neoadjuvant chemoradiotherapy (nCRT), there are no reliable indicators to accurately predict pathological complete response (pCR) before surgery. For patients with clinical complete response (cCR), a "Watch and Wait" (WW however, its ability to predict pCR needs to be improved. In this prospective cohort study, we explored the value of circulating tumor DNA (ctDNA) in combination with MRI in the prediction of pCR before su...
#1Dakui Luo (Fudan University Shanghai Medical College)H-Index: 6
#2Yufei Yang (Fudan University Shanghai Medical College)
Last. Xinxiang Li (Fudan University Shanghai Medical College)H-Index: 17
view all 7 authors...
Late recurrence (five or more years) after radical resection of colorectal cancer is rare. Our present study aims to investigate the features of late recurrence in stage I-III colorectal cancer. A total of 9754 stage I-III colorectal cancer patients who underwent radical surgery without receiving neoadjuvant therapy in Fudan University Shanghai Cancer Center were enrolled in this study. These patients were divided into three groups: early recurrence (3 month-2 years), intermediate recurrence (2 ...
#1Senlin Zhao (Fudan University)H-Index: 1
#2Bingjie Guan (SJTU: Shanghai Jiao Tong University)H-Index: 1
Last. Dongwang Yan (SJTU: Shanghai Jiao Tong University)H-Index: 25
view all 12 authors...
Glycolysis plays a crucial role in reprogramming the metastatic tumor microenvironment. A series of lncRNAs have been identified to function as oncogenic molecules by regulating glycolysis. However, the roles of glycolysis-related lncRNAs in regulating colorectal cancer liver metastasis (CRLM) remain poorly understood. In the present study, the expression of the glycolysis-related lncRNA MIR17HG gradually increased from adjacent normal to CRC to the paired liver metastatic tissues, and high MIR1...
Lymph node metastasis (LNM) is closely related to the postoperative recurrence of colorectal cancer (CRC), and greatly affects patient survival. Conducting Gene set variation analysis (GSVA) and gene set enrichment analysis (GSEA), we found that the epithelial-mesenchymal transition (EMT) signaling pathway is the signaling pathway most relevant to the process of LNM. An EMT-related gene signature was identified from a discovery dataset obtained 489 patients using LIMMA and LASSO Cox methods. Six...
#1Yuchen WuH-Index: 8
#2Tianan Guo (Fudan University)H-Index: 2
Last. Ye XuH-Index: 23
view all 7 authors...
#9Junxin WuH-Index: 8
#10Xin Wang (Sichuan University)H-Index: 55
#1Gong Chen (Peking Union Medical College)H-Index: 27
#2Junjie Peng (Fudan University)H-Index: 18
Last. Feng Wang (SYSU: Sun Yat-sen University)H-Index: 24
view all 18 authors...
BACKGROUND Precise methods for postoperative risk stratification to guide the administration of adjuvant chemotherapy (ACT) in localized colorectal cancer (CRC) are still lacking. Here, we conducted a prospective, observational, and multicenter study to investigate the utility of circulating tumor DNA (ctDNA) in predicting the recurrence risk. METHODS From September 2017 to March 2020, 276 patients with stage II/III CRC were prospectively recruited in this study and 240 evaluable patients were r...
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