Carla Sini
Vita-Salute San Raffaele University
IrradiationPhysicsInternal medicineRadiologyUrologySurgeryOncologyProbability distributionAtomic physicsMaterials scienceTomotherapyAdjuvantUrinary incontinenceNeuroendocrine tumorsContouringProstatectomyLymphDiarrheaProstate cancerWhole-PelvisToxicityNuclear medicinePost prostatectomy radiotherapyIn patientPelvic radiotherapyPost prostatectomyIntestinal toxicityObserver variationMathematicsComputer scienceRadiation therapyProtonTerm (time)Medicine
54Publications
9H-index
182Citations
Publications 54
Newest
#1Andrea BresolinH-Index: 1
#2A. FaiellaH-Index: 5
Last. Cesare CozzariniH-Index: 43
view all 24 authors...
Abstract Background and purpose To assess bowel dose-volume relationships for acute patient-reported intestinal symptoms of patients treated with whole-pelvis intensity-modulated radiotherapy (WPRT) for prostate cancer. Materials and methods Complete data of 415 patients enrolled in a multi institute, prospective trial (#NCT02803086) treated with radical (31%), adjuvant (33%) and salvage (36%) intent at a median dose to pelvic nodes/lymph-nodal area of 53Gy were available. The most severe change...
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#1Giulia BenedettiH-Index: 14
#2M. MoriH-Index: 5
Last. Francesco De CobelliH-Index: 45
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PURPOSE To assess the ability of radiomic features (RF) extracted from contrast-enhanced CT images (ceCT) and non-contrast-enhanced (non-ceCT) in discriminating histopathologic characteristics of pancreatic neuroendocrine tumors (panNET). METHODS panNET contours were delineated on pre-surgical ceCT and non-ceCT. First- second- and higher-order RF (adjusted to eliminate redundancy) were extracted and correlated with histological panNET grade (G1 vs G2/G3), metastasis, lymph node invasion, microsc...
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#1M. MoriH-Index: 5
#2Giulia BenedettiH-Index: 14
Last. Francesco De CobelliH-Index: 45
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Abstract Purpose The aim of this study was to quantify the impact of CT delineation uncertainty of pancreatic neuroendocrine neoplasms (panNEN) on Radiomic features (RF). Methods Thirty-one previously operated patients were considered. Three expert radiologists contoured panNEN lesions on pre-surgical high-resolution contrast-enhanced CT images and contours were transferred onto pre-contrast CT. Volume agreement was quantified by the DICE index. After images resampling and re-binning, 69 RF were...
11 CitationsSource
#1Lucia PernaH-Index: 17
#2M. MoriH-Index: 5
Last. C. FiorinoH-Index: 7
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Purpose To assess inter-fraction bowel loops (BL) motion and quantify its impact on BL DVHs in prostate radiotherapy including pelvic nodes irradiation. Methods Ten patients treated by Helical Tomotherapy, with adjuvant (5) or radical (5) intent, delivering 52.5/51.8 Gy to pelvic-nodes in 30/28 fractions respectively, were enrolled. For each patient, BL contours were drawn on fifteen daily MVCTs, using a validated method for segmentation: BL were propagated from the planning CT to in-room MVCTs ...
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#1Carla SiniH-Index: 9
#2M. MoriH-Index: 5
Last. C. FiorinoH-Index: 7
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Purpose High accuracy in delineating pancreatic neuroendocrine tumors (NET) is a pre-requisite for the assessment of CT-based biomarkers, including radiomic features (RF). The aim of this study was to quantify inter-observer variability in delineating NET on CT images and its impact on RF. Methods Three radiologists contoured volumes of 32 NET patients. The contours were delineated using arterial or venous phase. The contours delineated on contrast enhanced images were overlayed onto CT images a...
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#1Nicola DinapoliH-Index: 21
#1Nicola DinapoliH-Index: 22
Last. Vincenzo Valentini (UCSC: Catholic University of the Sacred Heart)H-Index: 66
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Purpose The objective of this study is finding an intensity based histogram (IBH) signature to predict pathologic complete response (pCR) probability using only pre-treatment magnetic resonance (MR) and validate it externally in order to create a workflow for the external validation of an MR IBH signature and to apply the model out of the environment where it has been tuned. The impact of pCR and the final predictors on the survival outcome were also evaluated. Methods and Materials Three center...
35 CitationsSource
#1Tiziana RancatiH-Index: 27
#2Carla SiniH-Index: 9
Last. Cesare CozzariniH-Index: 43
view all 25 authors...
1 CitationsSource
#1Fernando MunozH-Index: 11
#2Pietro GabrieleH-Index: 23
Last. Cesare CozzariniH-Index: 43
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#1Pietro GabrieleH-Index: 23
#2Barbara AvuzziH-Index: 11
Last. Cesare CozzariniH-Index: 43
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#1Lucia PernaH-Index: 17
#2M. MoriH-Index: 5
Last. C. FiorinoH-Index: 7
view all 7 authors...
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