Jorge R. Kizer
University of California, San Francisco
Internal medicineEndocrinologyCardiologyProspective cohort studyHazard ratioInsulin resistanceHeart failureDiseaseAtrial fibrillationBody mass indexPopulationCardiovascular healthConfidence intervalMyocardial infarctionProportional hazards modelRisk factorStrokeDiabetes mellitusMedicineCohort
Publications 324
BACKGROUND Persistent inflammation in HIV infection is associated with elevated cardiovascular disease risk, even with viral suppression. Identification of novel surrogate biomarkers can enhance cardiovascular disease risk stratification and suggest novel therapies. We investigated the potential of IL-32, a proinflammatory multi-isoform cytokine, as a biomarker for subclinical carotid artery atherosclerosis in virologically-suppressed women living with HIV (WLWH). METHODS AND RESULTS Nested with...
#1Monali Shah (RU: Rutgers University)
#2Carlos J. Rodriguez (Albert Einstein College of Medicine)H-Index: 4
Last. John S. Gottdiener (UMB: University of Maryland, Baltimore)H-Index: 106
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Heart failure (HF) and myocardial infarction are serious complications of major noncardiac surgery in older adults. Many factors can contribute to the development of HF during the postoperative period. The incidence of, and risk factors for, procedure-associated heart failure (PHF) occurring at the time of, or shortly after, medical procedures in a population-based sample ≥ 65 years of age have not been fully characterized, particularly in comparison with HF not proximate to medical procedures. ...
#1David S. Owens (UW: University of Washington)H-Index: 25
#2Traci M. Bartz (UW: University of Washington)H-Index: 40
Last. Jorge R. KizerH-Index: 60
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OBJECTIVES Current estimates of aortic stenosis (AS) frequency have mostly relied on cross-sectional echocardiographic or longitudinal administrative data, making understanding of AS burden incomplete. We performed case adjudications to evaluate the frequency of AS and assess differences by age, sex and race in an older cohort with long-term follow-up. METHODS We developed case-capture methods using study echocardiograms, procedure and diagnosis codes, heart failure events and deaths for targete...
1 CitationsSource
#1Anna E. BortnickH-Index: 5
#2Sanyog G. ShitoleH-Index: 8
Last. Jorge R. KizerH-Index: 60
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BACKGROUND Higher residual anatomic disease was associated with increased mortality in a recent randomized controlled trial of revascularization after ST-elevation myocardial infarction (STEMI). Less is known about the impact of residual disease post-STEMI in race-ethnic minorities. METHODS Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX)- II (SS-II) score is an established scoring method for anatomic disease and prevalent co-morbidities to describe pati...
#1Julio A. Lamprea-Montealegre (UCSF: University of California, San Francisco)H-Index: 8
#2Alice M. Arnold (UW: University of Washington)H-Index: 69
Last. Jorge R. KizerH-Index: 60
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Background: Advanced glycation end-products (AGEs) have been linked to cardiovascular disease (CVD) in populations with and without diabetes. There are limited data, however, regarding the longitud...
#1Seth B Newman (Montefiore Medical Center)
#2Vaishnavi Kundel (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 3
Last. Neomi A. Shah (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 9
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Study objectives Evaluate the association between obstructive sleep apnea (OSA), coronary artery calcium (CAC) density, and cardiovascular events in the Multi-Ethnic Study of Atherosclerosis (MESA). Methods We analyzed 1041 participants with non-zero CAC scores who had polysomnography and CAC density data from the fifth examination of MESA. OSA was defined as apnea-hypopnea index [AHI] ≥ 15 events/hour. Multivariable linear regression models were used to evaluate the independent association betw...
#1Sanyog G. ShitoleH-Index: 8
#2Jason M. Lazar (SUNY: State University of New York System)H-Index: 3
Last. Jorge R. KizerH-Index: 60
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Background HIV and HCV have each been linked with cardiac dysfunction. Studies of HIV have often lacked appropriate controls and primarily involved men, while data for HCV are sparse. Methods We performed repeat echocardiography over a median interval of 12 years in participants from the Women's Interagency HIV Study in order to evaluate the relationships of HIV and HCV with incident left ventricular (LV) dysfunction (systolic or diastolic). Results Of the 311 women included (age 39 ± 9), 70% we...
#1Mohamed El-Far (UdeM: Université de Montréal)H-Index: 19
#2Madeleine Durand (UdeM: Université de Montréal)H-Index: 16
Last. Cécile Tremblay (UdeM: Université de Montréal)H-Index: 32
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Despite the success of antiretroviral therapy (ART), people living with HIV (PLWH) are still at higher risk for cardiovascular diseases (CVDs) that are mediated by chronic inflammation. Identification of novel inflammatory mediators with the inherent potential to be used as CVD biomarkers and also as therapeutic targets is critically needed for better risk stratification and disease management in PLWH. Here, we investigated the expression and potential role of the multi-isoform proinflammatory c...