Emiliano Votta
Polytechnic University of Milan
AnatomyInternal medicineRadiologyFinite element methodBiomedical engineeringSurgeryMagnetic resonance imagingCardiologySystoleBiomechanicsHemodynamicsMaterials scienceMitral valveVentricleFluid–structure interactionAortic valveBicuspid aortic valveAortic rootPatient specificComputer scienceMedicineCardiac cycle
152Publications
24H-index
2,088Citations
Publications 153
Newest
#1Silvia Pozzi (Polytechnic University of Milan)H-Index: 1
#2Alberto Redaelli (Polytechnic University of Milan)H-Index: 49
Last. Paolo Zunino (Polytechnic University of Milan)H-Index: 28
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In this work we propose a mathematical and numerical model to describe the early stages of atherosclerotic plaque formation, which is based on the interaction of processes with different spatial and temporal scales. A fluid–structure interaction problem, used to describe the cardiovascular mechanics arising between blood and the artery wall, is coupled to a set of differential problems describing the evolution of solute concentrations. In order to manage the multiscale-in-space nature of the inv...
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#2A Riva (Polytechnic University of Milan)
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#1Michal Jaworek (Polytechnic University of Milan)H-Index: 4
#2Andrea ManginiH-Index: 16
Last. Riccardo Vismara (Polytechnic University of Milan)H-Index: 15
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Transcatheter therapies are emerging for functional mitral regurgitation (FMR) treatment, however there is lack of pathological models for their preclinical assessment. We investigated the applicability of deer hearts for this purpose.8 whole deer hearts were housed in a pulsatile flow bench. At baseline, all mitral valves featured normal coaptation. The pathological state was induced by 60-minutes intraventricular constant pressurization. It caused mitral annulus dilation (antero-posterior diam...
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#1Alessandra Riva (Polytechnic University of Milan)
#2Francesco Sturla (Polytechnic University of Milan)H-Index: 11
Last. Emiliano Votta (Polytechnic University of Milan)H-Index: 24
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Abstract Blood is generally modeled as a Newtonian fluid, assuming a standard and constant viscosity; however, this assumption may not hold for the highly pulsatile and recirculating intracavitary flow in the left ventricle (LV), hampering the quantification of fluid dynamic indices of potential clinical relevance. Herein, we investigated the effect of three viscosity models on the patient-specific quantification of LV blood energetics, namely on viscous energy loss ( EL ), from 4D Flow magnetic...
1 CitationsSource
#1G Rossini (Polytechnic University of Milan)H-Index: 1
#1G. Rossini (Polytechnic University of Milan)
Last. Emiliano Votta (Polytechnic University of Milan)H-Index: 24
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A Finite Element workflow for the multiscale analysis of the aortic valve biomechanics was developed and applied to three physiological anatomies with the aim of describing the aortic valve interstitial cells biomechanical milieu in physiological conditions, capturing the effect of subject-specific and leaflet-specific anatomical features from the organ down to the cell scale. A mixed approach was used to transfer organ-scale information down to the cell-scale. Displacement data from the organ m...
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#2Hector I. Michelena (Mayo Clinic)H-Index: 47
Last. Amalia ForteH-Index: 15
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Abstract The current management of aortic dilatation associated with congenital bicuspid aortic valve (BAV aortopathy) is based on dimensional parameters (diameter of the aneurysm, growth of the diameter over time) and few other criteria. The disease is however heterogeneous in terms of natural and clinical history and risk of acute complications, i.e. aortic dissection. Dimensional criteria are now admitted to have limited value as predictors of such complications. Thus, novel principles for ri...
15 CitationsSource
#2Matteo Frigelli (Polytechnic University of Milan)H-Index: 1
Last. Emiliano Votta (Polytechnic University of Milan)H-Index: 24
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Abstract Objective To elucidate the mechanisms of left ventricle (LV) functional recovery in terms of endocardial contractility and synchronicity after surgical ventricular reconstruction (SVR). Methods Real-time 3D transthoracic echocardiography (RT3DTTE) was performed on twenty patients with anterior LV remodelling and ischemic heart failure (HF) before SVR and at 6-months follow-up, and on 15 healthy controls matched by age and body surface area. RT3DTTE datasets were analysed through TomTec ...
2 CitationsSource
#1Silvia Pozzi (Polytechnic University of Milan)H-Index: 1
#2Maurizio Domanin (University of Milan)H-Index: 9
Last. Christian Vergara (Polytechnic University of Milan)H-Index: 24
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We propose a surrogate model for the fluid-structure interaction (FSI) problem for the study of blood dynamics in carotid arteries in presence of plaque. This is based on the integration of a numerical model with subject-specific data and clinical imaging. We propose to model the plaque as part of the tissues surrounding the vessel wall through the application of an elastic support boundary condition. In order to characterize the plaque and other surrounding tissues, such as the close-by jugular...
1 CitationsSource
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#1Giordano Tasca (Polytechnic University of Milan)H-Index: 12
#2Matteo Selmi (Polytechnic University of Milan)H-Index: 5
Last. Emiliano Votta (Polytechnic University of Milan)H-Index: 24
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In Sleeve procedure, the leaflets-sinus unit is maintained. We hypothesized that this feature partially preserves aortic root dynamics and leaflets kinematics and limits tensions in the leaflets. We tested our hypothesis based on in vivo and computational assessment of leaflets and aortic root dynamics. Aortic root and aortic leaflet kinematics was assessed by transthoracic echocardiography in 10 patients treated with the Sleeve procedure and in 10 healthy patients. Numerical calculations with t...
2 CitationsSource