Rachele Ciccocioppo
University of Verona
Internal medicinePathologyStromal cellReceptorTissue transglutaminaseApoptosisMesenchymal stem cellImmunologyLamina propriaInflammatory bowel diseaseDiseaseCrohn's diseaseCoeliac diseaseStem cellIn patientIntestinal mucosaCancer researchMedicineBiologyImmune systemGastroenterology
218Publications
30H-index
3,158Citations
Publications 218
Newest
#1Sowmya ViswanathanH-Index: 19
#2Rachele Ciccocioppo (University of Verona)H-Index: 30
Last. Yufang Shi (Soochow University (Suzhou))H-Index: 84
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Abstract null null The Cellular Therapy Coding and Labeling Advisory Group of the International Council for Commonality in Blood Banking Automation and the International Society for Cell & Gene Therapy mesenchymal stromal cell (MSC) committee are providing specific recommendations on abbreviating tissue sources of culture-adapted MSCs. These recommendations include using abbreviations based on the ISBT 128 terminology model that specifies standard class names to distinguish cell types and tissue...
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#1Rachele Ciccocioppo (University of Verona)H-Index: 30
#2Davide Gibellini (University of Verona)H-Index: 40
Last. Vincenzo Bronte (University of Verona)H-Index: 82
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Coronavirus disease 2019 (COVID-19) may result in a life-threatening condition due to a hyperactive immune reaction to severe acute respiratory syndrome-coronavirus-2 infection, for which no effective treatment is available. Based on the potent immunomodulatory properties of mesenchymal stromal cells (MSCs), a growing number of trials are ongoing. This prompted us to carry out a thorough immunological study in a patient treated with umbilical cord-derived MSCs and admitted to the Intensive Care ...
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#1Giovanni Arpa (UNIPV: University of Pavia)H-Index: 6
#2Alessandro Vanoli (UNIPV: University of Pavia)H-Index: 24
Last. Enrico Solcia (UNIPV: University of Pavia)H-Index: 89
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Most Crohn's disease-associated small bowel carcinomas (CrD-SBCs) are diagnosed in advanced stage and have poor prognosis. To improve diagnosis and therapy, a better knowledge of tumour precancerous lesions, histotypes and prognostic factors is needed. We investigated histologically and immunohistochemically 52 CrD-SBCs and 51 small bowel carcinomas unrelated to inflammatory disease, together with their tumour-associated mucosa, looking for Crohn-selective changes. Histologic patterns and phenot...
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#1Sandra Mersakova (Comenius University in Bratislava)H-Index: 7
#2Zora Lasabova (Comenius University in Bratislava)H-Index: 14
Last. Peter Mikolajčík (Comenius University in Bratislava)H-Index: 2
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Colorectal cancer (CRC) is one of the leading cancers in both genders. TNM staging system is still the most commonly used tumor classification and prognostic system. The disadvantage of TNM is that the prognostic information it provides is incomplete, and patients with the same histological tumor stages may differ significantly in the clinical outcome. Therefore, the identification of new prognostic parameters is crucial. The carcinogenic process that gives rise to an individual tumor is unique ...
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#1Allison L. Speer (University of Texas Health Science Center at Houston)H-Index: 12
#2Xi Ren (CMU: Carnegie Mellon University)H-Index: 15
Last. Giuseppe Orlando (Wake Forest Baptist Medical Center)H-Index: 56
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Abstract The field of regenerative medicine is developing technologies that, in the near future, will offer alternative approaches to either cure diseases affecting the gastrointestinal tract or slow their progression by leveraging the intrinsic ability of our tissues and organs to repair after damage. This article will succinctly illustrate the three technologies that are closer to clinical translation—namely, human intestinal organoids, sphincter bioengineering and decellularization, whereby t...
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#1Karin Jasek (Comenius University in Bratislava)H-Index: 9
#2Marian Grendar (Comenius University in Bratislava)H-Index: 13
Last. Zora Lasabova (Comenius University in Bratislava)H-Index: 14
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Single nucleotide polymorphisms can create a genetic microenvironment in some tumors that affects the course of treatment, resistance, etc. Whether single nucleotide polymorphisms have an impact on gastrointestinal stromal tumor (GIST) development and disease progression is not yet accurately verified. KIT SNPM541L in exon 10 correlates with a worse prognosis of many cancers. The impact of KIT SNPM541L in GISTs is relatively unknown and, therefore, its analyses could have potential in patient th...
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#1Rachele Ciccocioppo (University of Verona)H-Index: 30
#2Caterina Mengoli (UNIPV: University of Pavia)H-Index: 6
Last. Fausto BaldantiH-Index: 70
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Human Cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) are endowed with the ability of establishing lifelong latency in human hosts and reactivating in immunocompromised subjects, including patients suffering from ulcerative colitis (UC). We, therefore, aimed to investigate virus-specific immunity in UC patients. A cohort of 24 UC patients (14 responders and 10 refractory to therapy) and 26 control subjects was prospectively enrolled to undergo virus-specific serology (by ELISA assay) and ass...
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#1Annalisa Schiepatti (UNIPV: University of Pavia)H-Index: 8
#2Sara Bacchi (UNIPV: University of Pavia)H-Index: 2
Last. Rachele Ciccocioppo (University of Verona)H-Index: 30
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Abstract Background Duodenal dysbiosis has been suggested to possibly influence the clinical manifestations of coeliac disease (CD), both at onset and when symptoms persist despite a gluten-free diet (GFD). AIMS To evaluate the relationship between duodenal microbiota composition and: i) clinical phenotype of untreated CD (UCD); ii) presence and type of persistent symptoms despite a satisfactory serological and histological response to a strict GFD. Methods Duodenal microbiota was analyzed by 16...
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#1Na Song (Harvard University)H-Index: 1
#2Hiroaki Wakimoto (Harvard University)H-Index: 57
Last. Khalid Shah (Harvard University)H-Index: 47
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The Coronavirus disease 2019 (COVID-19) pandemic has grown to be a global public health crisis with no safe and effective treatments available yet. Recent findings suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the coronavirus pathogen that causes COVID-19, could elicit a cytokine storm that drives edema, dysfunction of the airway exchange, and acute respiratory distress syndrome in the lung, followed by acute cardiac injury and thromboembolic events leading to multio...
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