Georgina Arrambide
Autonomous University of Barcelona
Internal medicineRadiologyPathologyMagnetic resonance imagingMcDonald criteriaProspective cohort studyImmunologyHazard ratioOptic neuritisDiseaseMyelin oligodendrocyte glycoproteinMultiple sclerosisExpanded Disability Status ScaleClinically isolated syndromeNeuromyelitis opticaConfidence intervalProportional hazards modelMedicineCohortGastroenterology
58Publications
20H-index
1,608Citations
Publications 65
Newest
#1Steve Simpson-Yap (University of Melbourne)H-Index: 4
#2Edward De Brouwer (Katholieke Universiteit Leuven)H-Index: 3
Last. Geys L (University of Hasselt)H-Index: 1
view all 47 authors...
BACKGROUND: People with multiple sclerosis (MS) are a vulnerable group for severe COVID- 19, particularly those taking immunosuppressive disease-modifying therapies (DMTs). We examined the characteristics of COVID-19 severity in an international sample of people with MS. METHODS: Data from 12 data-sources in 28 countries were aggregated (sources could include patients from 1-12 countries). Demographic (age, sex), clinical (MS-phenotype, disability), and DMT (untreated, alemtuzumab, cladribine, d...
1 CitationsSource
#1Jordi RíoH-Index: 40
#2Alex Rovira (Autonomous University of Barcelona)H-Index: 76
Last. Luciana MidagliaH-Index: 12
view all 20 authors...
Different treatment response scoring systems in treated MS patients exist. The objective was to assess the long-term predictive value of these systems in RRMS patients treated with self-injectable DMTs. RRMS-treated patients underwent brain MRI before the onset of therapy and 12 months thereafter, and neurological assessments every 6 months. Clinical and demographic characteristics were collected at baseline. After the first year of treatment, several scoring systems [Rio score (RS), modified Ri...
Source
#1Mar Tintoré (Autonomous University of Barcelona)H-Index: 62
#2Alvaro Cobo-Calvo (Autonomous University of Barcelona)H-Index: 13
Last. María Jesús Arévalo (Autonomous University of Barcelona)H-Index: 15
view all 21 authors...
Background and Objectives null To explore whether time to diagnosis, time to treatment initiation, and age to reach disability milestones have changed in patients with clinically isolated syndrome (CIS) according to different multiple sclerosis (MS) diagnostic criteria periods. null Methods null This retrospective study was based on data collected prospectively from the Barcelona-CIS cohort between 1994 and 2020. Patients were classified into 5 periods according to different MS criteria, and the...
2 CitationsSource
#1Steve Simpson-Yap (University of Melbourne)H-Index: 4
#2Edward De BrouwerH-Index: 3
Last. Tina ParciakH-Index: 3
view all 44 authors...
Abstract null null null null null null null null null null null null null null null null null null null null null null null null null null null null null null null null Background null null null null null null null null null null null null null null null null null People with multiple sclerosis (MS) are a vulnerable group for severe COVID-19, particularly those taking immunosuppressive disease-modifying therapies (DMTs). We examined the characteristics of COVID-19 severity in an international sa...
Source
#1Francisco Pérez-Miralles (Autonomous University of Barcelona)H-Index: 16
#2Jordi Río (Autonomous University of Barcelona)H-Index: 40
Last. Jaume Sastre-Garriga (Autonomous University of Barcelona)H-Index: 52
view all 11 authors...
PURPOSE Brain volume changes (BVC) on therapy in MS are being considered as predictor for treatment response at an individual level. We ought to assess whether adding BVC as a factor to monitor interferon-beta response improves the predictive ability of the (no) evidence of disease activity (EDA-3) and Rio score (RS-3) criteria for confirmed disability progression in a historical cohort. METHODS One hundred one patients from an observational cohort treated with interferon-beta were assessed for ...
Source
#1Georgina Arrambide (Autonomous University of Barcelona)H-Index: 20
Last. Mayra Gómez-MorenoH-Index: 1
view all 40 authors...
Objective null To understand COVID-19 characteristics in people with multiple sclerosis (MS) and identify high-risk individuals due to their immunocompromised state resulting from the use of disease-modifying treatments. null Methods null Retrospective and multicenter registry in patients with MS with suspected or confirmed COVID-19 diagnosis and available disease course (mild = ambulatory; severe = hospitalization; and critical = intensive care unit/death). Cases were analyzed for associations ...
2 CitationsSource
#1Susana Otero-Romero (Autonomous University of Barcelona)H-Index: 12
#2Luciana Midaglia (Autonomous University of Barcelona)H-Index: 12
Last. Mar Tintoré (Autonomous University of Barcelona)H-Index: 62
view all 21 authors...
Objective to evaluate the effect of menopause on disability accumulation in women followed from their clinically isolated syndrome (CIS). Methods We examined the longitudinal changes in EDSS from CIS until the last follow-up in women belonging to the Barcelona CIS prospective cohort, followed through their menopausal transition. The analysis is based on 13,718 EDSS measurements with an average of 28 EDSS per patient. Differences in EDSS trajectories between menopausal and non-menopausal women, c...
2 CitationsSource
#1Luciana Midaglia (Autonomous University of Barcelona)H-Index: 12
#2Jaume Sastre-Garriga (Autonomous University of Barcelona)H-Index: 52
Last. Alex Rovira (Autonomous University of Barcelona)H-Index: 76
view all 17 authors...
BACKGROUND Multiple sclerosis (MS) misdiagnosis may cause physical and emotional damage to patients. OBJECTIVES The objective of this study is to determine the frequency and characteristics of MS misdiagnosis in patients referred to the Multiple Sclerosis Centre of Catalonia. METHODS We designed a prospective study including all new consecutive patients referred to our centre between July 2017 and June 2018. Instances of misdiagnosis were identified, and referral diagnosis and final diagnosis we...
3 CitationsSource
#1Steve Simpson-Yap (University of Melbourne)H-Index: 4
#2Edward De BrouwerH-Index: 3
Last. Liesbet M. Peeters (University of Hasselt)H-Index: 4
view all 47 authors...
Background: People with multiple sclerosis (MS) are a vulnerable group for severe COVID-19, particularly those taking immunosuppressive disease-modifying therapies (DMTs). We examined the characteristics of COVID-19 severity in an international sample of people with MS. Methods: Data from 12 data-sources in 28 countries were aggregated. Demographic and clinical covariates were queried, alongside COVID-19 clinical severity outcomes, hospitalisation, admission to ICU, requiring artificial ventilat...
11 CitationsSource
#1Angela Vidal-Jordana (Autonomous University of Barcelona)H-Index: 21
#2Alex Rovira (Autonomous University of Barcelona)H-Index: 76
Last. Mar Tintoré (Autonomous University of Barcelona)H-Index: 62
view all 20 authors...
Objective: To assess the added value of the optic nerve region (by using visual evoked potentials-VEPs-) to the current diagnostic criteria. Methods: From the Barcelona clinically isolated syndrome (CIS) cohort, patients with complete information to assess dissemination in space (DIS), the optic nerve region, and dissemination in time (DIT) at baseline (n=388) were selected. Modified DIS (modDIS) criteria were constructed by adding the optic nerve to the current DIS regions. The DIS and modDIS c...
2 CitationsSource