Kenzo Hirao
Tokyo Medical and Dental University
Internal medicineSurgeryCardiologySinus rhythmCatheter ablationVentricular tachycardiaHeart failureCoronary sinusAblationAtrial fibrillationAtrial tachycardiaElectrocardiographyTachycardiaPulmonary veinCatheterSuperior vena cavaLeft atrialIn patientAnesthesiaIncidence (epidemiology)Medicine
Publications 467
#1Atsuhiko YagishitaH-Index: 10
#2Yasuteru YamauchiH-Index: 18
Last. Akihiko NogamiH-Index: 36
view all 5 authors...
Abstract Malignant ventricular arrhythmias arising from the pulmonary artery rarely occur in patients without structural heart disease. We highlight the feasibility and efficacy of a circular cathe...
#1Masaaki ShojiH-Index: 2
#2Koji InabaH-Index: 14
Last. Paul C. Zei (Brigham and Women's Hospital)H-Index: 16
view all 16 authors...
Although catheter ablation is an effective therapy for atrial fibrillation (AF), risks remain and improved efficacy is desired. Stereotactic radiotherapy is a well-established therapy used to noninvasively treat malignancies with precision. We sought to evaluate stereotactic arrhythmia radioablation (STAR) as a therapeutic option for treating AF. Three cancer patients with drug refractory AF were enrolled. Planning software using 3-D CT of the left atrium was used to design a desired ablation vo...
#1Anat Milman (TAU: Tel Aviv University)H-Index: 14
#2Elijah R. Behr (St George’s University Hospitals NHS Foundation Trust)H-Index: 55
Last. Jimmy Jm Juang (NTU: National Taiwan University)
view all 44 authors...
BACKGROUND Brugada syndrome (BrS) is associated with mutations in the cardiac sodium channel gene, SCN5A. However, genetic studies of patients with BrS with arrhythmic events have been limited. We sought to compare various clinical, ECG, and electrophysiological parameters according to SCN5A genotype in a large cohort of BrS probands with first arrhythmic event. METHODS Survey on Arrhythmic Events in Brugada Syndrome is a survey of 10 Western and 4 Asian countries, gathering 678 patients with Br...
#1Yuka Shiheido-Watanabe (Tokyo Medical and Dental University)H-Index: 2
#2Yasuhiro Maejima (Tokyo Medical and Dental University)H-Index: 33
Last. Tetsuo Sasano (Tokyo Medical and Dental University)H-Index: 27
view all 9 authors...
Summary null null This study sought to show the mechanism of how to ameliorate experimental autoimmune myocarditis (EAM) by administering dipeptidyl peptidase 4 (DPP-4) inhibitor linagliptin. The number of RAR-related orphan nuclear receptor gamma–positive Th17 cells infiltrated to the EAM myocardium was significantly attenuated by linagliptin treatment. Tandem mass spectrometry–based analysis demonstrated that DPP-4 binds to cathepsin G in EAM hearts, thereby protecting cathepsin G activity thr...
#1Keita Watanabe (Tokyo Medical and Dental University)H-Index: 4
#2Junichi NittaH-Index: 10
Last. Tetsuo Sasano (Tokyo Medical and Dental University)H-Index: 27
view all 10 authors...
PURPOSE Progress of balloon devices for pulmonary vein (PV) isolation in atrial fibrillation (AF) has been remarkable. However, these techniques were specialized in pulmonary vein treatment; predicting non-PV foci in advance is important to decide the treatment strategy. In this study, we investigate the predictors for paroxysmal AF. METHODS Subjects were consecutive paroxysmal AF patients who underwent high-dose isoproterenol provocation after PV isolation in the first session. The PV group (n ...
We report a 77-year-old human on renal dialysis for end-stage renal disease with heart failure and atrial fibrillation (AF) complicated by a high ventricular frequency. The underlying disease was thought as tachycardia-induced-cardiomyopathy. Intravenous infusion of amiodarone was initiated, and direct current cardioversion succeeded in converting AF to sinus rhythm. Then, excessive increases in the QT and Tpeak-Tend (Tp-e) intervals were seen and hypokalemia induced by hemodialysis led to the d...
#1Koji Higuchi (Cleveland Clinic)H-Index: 6
#2Oussama Wazni (Cleveland Clinic)H-Index: 64
Last. Tetsuo Sasano (Tokyo Medical and Dental University)H-Index: 27
view all 10 authors...
Objectives: The goal of this study was to retrospectively analyze the long-term outcome after persistent atrial fibrillation (AF) ablation by combining continuous wavelet transform (CWT) and left atrial (LA) voltage mapping. Background: CWT analysis is a frequency analysis to search the area of stable high frequency (stable pseudo frequency [sPF]) during AF. Methods: CWT analysis were performed in persistent AF (109 patients, 65{plus minus}10 years) pre-PVI in PVs, and 8 sites in LA to investiga...
Abstract Background and aims The nutritional risk of patients who undergo atrial fibrillation (AF) ablation varies. Its impact on the recurrence after ablation is unclear. We sought to evaluate the relationship between the nutritional risk and arrhythmia recurrence in patients who undergo AF ablation. Methods and results We enrolled 538 patients (median 67 years, 69.9% male) who underwent their first AF ablation. Their nutritional risk was evaluated using the pre-procedural geriatric nutritional...
#1Kaoru OkishigeH-Index: 21
#2Tatsuhiko HiraoH-Index: 5
Last. Kenzo Hirao (Tokyo Medical and Dental University)H-Index: 32
view all 9 authors...
Radiofrequency and cryoballoon applications around the pulmonary veins (PVs) could provoke a vagal reflex (VR) by modulating the intrinsic cardiac autonomic nervous system (ICANS).This study aimed to investigate the incidence, timing, and clinical impact of a VR provoked by a laser balloon application for a PV isolation (PVI).A total of 92 consecutive paroxysmal atrial fibrillation (PAF) patients underwent a laser balloon PVI of PAF. Acute changes in the heart rate and blood pressure were record...
#1Koichi InoueH-Index: 20
#2Kenzo HiraoH-Index: 32
Last. Jacre InvestigatorsH-Index: 2
view all 18 authors...
Abstract Background Catheter ablation (CA) is an important strategy for managing atrial fibrillation (AF). However, long-term anticoagulation strategies and clinical outcomes following CA, including thromboembolism and bleeding, have not yet been elucidated. Methods We established a prospective registry, called the JACRE registry, for patients on rivaroxaban or warfarin administration who received CA for AF. The outcomes up to 30 days following the procedure were reported previously. The present...
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