Alberto Briganti
Vita-Salute San Raffaele University
DissectionInternal medicineRadiologyUrologySurgeryOncologyStage (cooking)Hazard ratioCystectomyBiopsyProstateBiochemical recurrenceProstatectomyProstate cancerBladder cancerLymph nodeIn patientProportional hazards modelMedicineCohort
2,029Publications
96H-index
26.4kCitations
Publications 1533
Newest
#1Mike Wenzel (Goethe University Frankfurt)H-Index: 6
#2Christoph Würnschimmel (UdeM: Université de Montréal)H-Index: 3
Last. Luis A. Kluth (Goethe University Frankfurt)H-Index: 20
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Background null Recently, an increase in the rates of high-risk prostate cancer (PCa) was reported. We tested whether the rates of and low, intermediate, high and very high-risk PCa changed over time. We also tested whether the number of prostate biopsy cores contributed to changes rates over time. null Methods null Within the Surveillance, Epidemiology and End Results (SEER) database (2010-2015), annual rates of low, intermediate, high-risk according to traditional National Comprehensive Cancer...
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#1Abdulmajeed Aydh (Medical University of Vienna)H-Index: 4
#2Keiichiro Mori (Jikei University School of Medicine)H-Index: 8
Last. Pierre I. Karakiewicz (UdeM: Université de Montréal)H-Index: 116
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PURPOSE To evaluate the potential predictive value of the preoperative serum albumin to globulin ratio (AGR) for oncological outcomes in patients treated with radical prostatectomy (RP) for clinically non-metastatic prostate cancer (PCa). METHODS Pre-operative AGR was assessed in a multi-institutional cohort of 6041 patients treated with RP. Logistic regression analyses were performed to assess the association of the AGR with advanced disease. We performed Cox regression analyses to determine th...
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#1Carlo Andrea Bravi (UniSR: Vita-Salute San Raffaele University)H-Index: 10
#2M. DroghettiH-Index: 3
Last. Riccardo SchiavinaH-Index: 38
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Abstract null null Background null The optimal definition and prognostic significance of persistently elevated prostate-specific antigen (PSA) after salvage lymph node dissection (sLND) for node-only recurrent prostate cancer (PCa) remain unknown. null null null Objective null To assess the definition and clinical implications of persistently elevated PSA after sLND for node-only recurrent PCa after radical prostatectomy. null null null Design, setting, and participants null The study included 5...
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#1Neal D. ShoreH-Index: 56
#2Joan Palou Redorta (Autonomous University of Barcelona)H-Index: 16
Last. Gary D. Steinberg (NYU: New York University)H-Index: 5
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Abstract null null Aim null This review article summarizes the current clinical practice guidelines around disease definitions and risk stratifications, and the treatment of non-muscle-invasive bladder cancer (NMIBC). Recently completed and ongoing clinical trials of novel and investigational therapies in Bacillus Calmette-Guerin (BCG)-naive, BCG-recurrent, and BCG-unresponsive patient populations are also described, e.g., those involving immune checkpoint inhibitors, targeted therapies, other c...
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#1Gianluca Giannarini (Misericordia University)H-Index: 33
#2Neeraj Agarwal (HCI: Huntsman Cancer Institute)H-Index: 61
Last. Andrea NecchiH-Index: 35
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Novel immune checkpoint inhibitors hold promise for non-muscle-invasive bladder cancer. Cooperation between urologists and other multidisciplinary bladder cancer specialists can surmount the challenges involved in using these agents in bladder-sparing approaches. This strategy could deliver a new era of comprehensive evaluation and multimodal treatment for this patient population.
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#1Andrea Necchi (UniSR: Vita-Salute San Raffaele University)H-Index: 13
#2Alberto Martini (UniSR: Vita-Salute San Raffaele University)H-Index: 27
Last. Simone Scuderi (UniSR: Vita-Salute San Raffaele University)H-Index: 6
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Abstract null null Introduction null Advances in neoadjuvant therapy for patients with localized, nonmetastatic, upper tract urothelial carcinoma (UTUC) is needed. null null null Patients and methods null PURE-02 was a feasibility study enrolling individuals with UTUC, at clinical stage N0M0, with high-risk features according to the modified European Association of Urology definition, based on the presence of either: high-grade disease, multifocality, tumor size ≥2 cm, and/or hydronephrosis. The...
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#1Pawel Rajwa (Medical University of Silesia)H-Index: 5
#2Victor M. Schuettfort (UHH: University of Hamburg)H-Index: 5
Last. Hadi Mostafaei (Tabriz University of Medical Sciences)H-Index: 8
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Abstract null null Purpose null To evaluate the predictive and prognostic value of the Systemic Immune–inflammation Index (SII) in a large cohort of patients treated with radical prostatectomy (RP) for clinically non–metastatic prostate cancer (PCa). null null null Methods null We retrospectively analyzed our multicenter database comprising 6,039 consecutive patients. The optimal preoperative SII cut–off value was assessed with the Youden index calculated on a time–dependent receiver operating c...
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#1Claudia Collà Ruvolo (University of Naples Federico II)H-Index: 3
#2Christoph Würnschimmel (UniSR: Vita-Salute San Raffaele University)
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AIMS The European Association of Urology guideline for upper tract urothelial carcinoma (UTUC) relies on two grading system: 1973 World Health Organization (WHO) and 2004/2016 WHO. No consensus has been made which classification should supersede the other and both are recommended in clinical practice. We hypothesized that one may be superior to the other. METHODS Newly diagnosed non-metastatic UTUC patients treated with radical nephroureterectomy were abstracted from the Surveillance, Epidemiolo...
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#1Giuseppe Fallara (UniSR: Vita-Salute San Raffaele University)H-Index: 3
#2Marco Bandini (UniSR: Vita-Salute San Raffaele University)H-Index: 24
Last. Roberto Bertini (UniSR: Vita-Salute San Raffaele University)H-Index: 31
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The indications for adjuvant vascular endothelial growth factor-tyrosine kinase inhibitor (VEGF-TKI) agents after curative intent nephrectomy for renal cell carcinoma are still a matter of debate. The ASSURE, PROTECT and ATLAS trials have failed to meet their primary end-points. Conversely, S-TRAC has shown a disease free survival (DFS) benefit. To date, meta-analyses have repeatedly proved the absence of a clinical benefit, in term of DFS and overall survival (OS). Nevertheless, the results of ...
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#1Claudia Collà Ruvolo (University of Naples Federico II)H-Index: 3
#2Luigi Nocera (UdeM: Université de Montréal)H-Index: 5
Last. Fred Saad (UdeM: Université de Montréal)H-Index: 98
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PURPOSE Unmarried status is an established risk factor for worse cancer control outcomes in various malignancies. Moreover, several investigators observed worse outcomes in unmarried males, but not in females. This concept has not been tested in upper tract urothelial carcinoma and represents the topic of the study. METHODS Within Surveillance, Epidemiology and End Results database (2004-2016), we identified 8833 non-metastatic upper tract urothelial carcinoma patients treated with radical nephr...
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