Laura Pasquardini
University of Trento
Surface modificationAnalytical chemistryDetection limitOpticsAptamerAdsorptionBiosensorNanotechnologyX-ray photoelectron spectroscopyChemistryMaterials sciencePhotonicsChemical engineeringOptoelectronicsSiliconPhotonic crystalWhispering-gallery waveAdhesionFluorescenceResonator
Publications 81
#1Nunzio CennamoH-Index: 18
#2Laura PasquardiniH-Index: 15
Last. Luigi ZeniH-Index: 34
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Abstract A specific aptameric sequence has been immobilized on short polyethyleneglycol (PEG) interface on gold nano-film deposited on a D-shaped plastic optical fiber (POFs) probe, and the protein binding has been monitored exploiting the very sensitive surface plasmon resonance (SPR) phenomenon. The receptor-binding domain (RBD) of the SARS-CoV-2 spike glycoprotein has been specifically used to develop an aptasensor. Surface analysis techniques coupled to fluorescence microscopy and plasmonic ...
#1Laura Pasquardini (University of Trento)H-Index: 15
#2Alessandro Roncador (University of Trento)H-Index: 2
Last. Sandra Dirè (University of Trento)H-Index: 23
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Abstract The neuroscience field has increased enormously over the last decades, achieving the possible real application of neuronal cultures not only for reproducing neural architectures resembling in vivo tissues, but also for the development of functional devices. In this context, surface patterning for cell confinement is crucial, and new active materials together with new protocols for preparing substrates suitable for confining cells, guiding their processes in the desired configuration are...
The molecular imprinting of proteins is the process of forming biomimetics with entailed protein-recognition by means of a template-assisted synthesis. Protein-imprinted polymers (pMIPs) have been successfully employed in separations, assays, sensors, and imaging. From a technical point of view, imprinting a protein is both costly, for protein expression and purification, and challenging, for the preservation of the protein's structural properties. In fact, the imprinting process needs to guaran...
#1Laura PasquardiniH-Index: 15
#2Nunzio CennamoH-Index: 18
Last. Alessandra BossiH-Index: 28
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Postoperative pancreatic fistula (POPF), the major driver of morbidity and mortality following pancreatectomy, is caused by an abnormal communication between the pancreatic ductal epithelium and another epithelial surface containing pancreas-derived, enzyme-rich fluid. There is a strong correlation between the amylase content in surgically-placed drains early in the postoperative course and the development of POPF. A simple and cheap method to determine the amylase content from the drain effluen...
#1Carlotta Peruzzi (University of Parma)H-Index: 1
#2Silvia BattistoniH-Index: 10
Last. Salvatore IannottaH-Index: 31
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In several biomedical applications, the detection of biomarkers demands high sensitivity, selectivity and easy-to-use devices. Organic electrochemical transistors (OECTs) represent a promising class of devices combining a minimal invasiveness and good signal transduction. However, OECTs lack of intrinsic selectivity that should be implemented by specific approaches to make them well suitable for biomedical applications. Here, we report on a biosensor in which selectivity and a high sensitivity a...
#1Lorenzo LunelliH-Index: 18
Last. Cecilia PederzolliH-Index: 21
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Epitope imprinting is an effective strategy to prepare molecularly imprinted polymers (MIPs) for protein recognition. Indeed, the idea to use as a template just a fragment of the protein of interest, called the epitope, instead of the whole protein, presents some key advantages for the imprinting process, in particular: cutting the costs for MIP production and avoiding protein unfolding during the imprinting process, so to ultimately improve the quality of the stamped binding sites. How to selec...
#1A. Chiappini (fondazione bruno kessler)H-Index: 12
#1Andrea Chiappini (fondazione bruno kessler)H-Index: 22
Last. Alessandra BossiH-Index: 28
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Optical sensing, taking advantage of the variety of available optical structures, is a rapidly expanding area. Over recent years, whispering gallery mode resonators, photonic crystals, optical waveguides, optical fibers and surface plasmon resonance have been exploited to devise different optical sensing configurations. In the present review, we report on the state of the art of optical sensing devices based on the aforementioned optical structures and on synthetic receptors prepared by means of...
4 CitationsSource
#1Gabriele Frigenti (UniFI: University of Florence)H-Index: 3
#1G. Frigenti (UniFI: University of Florence)
Last. Silvia Soria (IFAC: International Federation of Accountants)H-Index: 21
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We report on chemical, biochemical and physical sensors based on whispering gallery mode resonators. We characterized the resonators, improved the mitigation of fluctuations, and developed different types of optical sensors, labelled and label-free sensors for chemical and biochemical sensing, and pressure, temperature and nanoparticle sensing.
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