Yoshiyuki Abe
Juntendo University
Internal medicineUnivariate analysisAntibodyAdverse effectRheumatologyImmunologyHazard ratioSurvival rateSystemic lupus erythematosusInterstitial lung diseaseRheumatoid arthritisDermatomyositisAutoimmune diseaseSingle CenterGlucocorticoidMyositisIn patientMonoclonal antibodyMedicineComplicationGastroenterology
26Publications
6H-index
102Citations
Publications 26
Newest
#1Yoshiyuki Abe (Juntendo University)H-Index: 6
#2Keigo Saeki (Nara Medical University)H-Index: 24
Last. Naoto Tamura (Juntendo University)H-Index: 19
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Objectives: Malignant rheumatoid arthritis (MRA) is defined as rheumatoid arthritis (RA) with systemic vasculitis or other severe extra-articular manifestations. Japan has a nationwide database for...
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#1Yasushi Matsushita (Juntendo University)
#2Makio Kusaoi (Juntendo University)H-Index: 12
Last. Toshio Naito (Juntendo University)H-Index: 19
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We retrospectively analyzed the characteristics and outcomes of five patients with COVID-19 who were received glucocorticoid (with or without pulse therapy) and therapeutic plasma exchange. The efficacy of the treatment was determined by whether the patient was able to be transferred from the COVID-19 exclusive ICU to the general ward. In comparing patients who received prednisolone pulse therapy (3 cases) with those who did not (2 cases), 2/3 (66%) and 0/2 (0%) patients could be discharged from...
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#1Yoshiyuki Abe (Juntendo University)H-Index: 6
#2Kurisu Tada (Juntendo University)H-Index: 10
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 4 authors...
Objectives. Mycophenolate mofetil (MMF) is the standard treatment for lupus nephritis. In Japan, it was approved for lupus nephritis in 2015. We investigated its real-world safety and effectiveness in Japanese patients with systemic lupus erythematosus (SLE). Methods. We analyzed the continuation rate, adverse events, and reasons for discontinuation of MMF in Japanese patients with SLE in a retrospective single-center study. We included 119 patients who received MMF from 31 July 2015 to 31 May 2...
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#1Yoshiyuki AbeH-Index: 6
#2Taiga KugaH-Index: 2
Last. Naoto TamuraH-Index: 19
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Background: This is an extended report of our study [1]. Anti-melanoma differentiation-associated gene 5 (MDA5) antibodies, which are closely related to interstitial lung disease (ILD) with or without rapid progression, are a type of myositis-specific autoantibody. Since rapid progressive-ILD (RP-ILD) with anti-MDA5 antibodies is refractory and fatal, intensive immunosuppressive therapy with combination calcineurin inhibitor, and intravenous pulse cyclophosphamide was developed, and was shown to...
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#1Masakazu MatsushitaH-Index: 10
#2Hirofumi AmanoH-Index: 20
Last. Naoto TamuraH-Index: 19
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Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology that affects mostly young women. Multiorgan complications and prolonged treatment significantly cause physical and mental stress in patients. Improving patients’ quality of life (QOL) in SLE treatment is essential. We examined the treatment effects on disease activity and QOL of SLE patients. Objectives: In recent years, lupus low disease activity state (LLDAS) has been proposed as a treatment targ...
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#1Yoshiyuki Abe (Juntendo University)H-Index: 6
#2Kazutoshi Fujibayashi (Juntendo University)H-Index: 11
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 9 authors...
Glucocorticoids (GCs) have long played a central role in the treatment of systemic lupus erythematosus (SLE), but these drugs have many adverse effects. We will determine whether rapid weekly GC tapering is non-inferior to conventional biweekly tapering in patients with severe SLE. This is a randomized, open-label, multicenter controlled trial. The primary outcome is the relapse-free survival rate at 52 weeks. The main secondary outcome is the prevalence of the Lupus Low Disease Activity State a...
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#1Yoshiyuki Abe (Juntendo University)H-Index: 6
#2Makio Kusaoi (Juntendo University)H-Index: 12
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 5 authors...
OBJECTIVES: We examined the effectiveness of plasma exchange (PE) therapy to reduce the mortality of rapidly progressive interstitial lung disease (RP-ILD) in patients positive for anti-melanoma differentiation-associated gene 5 (MDA5) antibodies. METHODS: Among 142 patients newly diagnosed with PM/DM or clinically amyopathic DM from 2008 to 2019 at our hospital, 10 were diagnosed with refractory RP-ILD and were positive for anti-MDA5 antibodies. PE was used as an adjunct to standard therapy and...
8 CitationsSource
#1Yoshiyuki Abe (Juntendo University)H-Index: 6
#2Ken Yamaji (Juntendo University)H-Index: 17
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 9 authors...
: Diffuse alveolar hemorrhage (DAH) is well known as a serious complication of microscopic polyangiitis (MPA). We examined the effectiveness of plasma exchange (PLEX) therapy to reduce mortality in Japanese DAH patients with MPA. This retrospective, double-center, observational cohort study included 20 DAH patients with MPA who were admitted to Juntendo University Hospital or Juntendo Koto Geriatric Medical Center between April 1998 and March 2018. The primary outcome was non-disease-specific mo...
2 CitationsSource
#1Nagachika Sugisaki (Juntendo University)H-Index: 4
#2Kurisu Tada (Juntendo University)H-Index: 10
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 8 authors...
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#1Yoshiyuki Abe (Juntendo University)H-Index: 6
#2Mariko Harada (Juntendo University)
Last. Naoto Tamura (Juntendo University)H-Index: 19
view all 5 authors...
AbstractObjectives: Secondary central nervous system vasculitis (SCNSV) is an extremely rare, refractory, and fatal disease in patients with giant cell arteritis (GCA). We compared the characterist...
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