Shuichiro Shiina
Juntendo University
Internal medicineRadiologySurgeryPathologyOncologyImmunologyHepatitis C virusHepatitis CCirrhosisRadiofrequency ablationCarcinomaHepatocellular carcinomaPercutaneous ethanol injectionPercutaneousLiver functionHepatologyCancer researchMedicineBiologyGastroenterology
Publications 310
#1Hironao Okubo (Juntendo University)H-Index: 9
#2Hitoshi Ando (Kanazawa University)H-Index: 32
Last. Akihito Nagahara (Juntendo University)H-Index: 35
view all 7 authors...
Abstract null null This prospective study examined the impact of genetic polymorphisms on the pharmacokinetics and clinical efficacy and safety of lenvatinib, a substrate of ATP-binding transporters, in a cohort of 48 Japanese patients with hepatocellular carcinoma (HCC). Pharmacokinetic studies were performed at the start of lenvatinib therapy (day 1) and on day 15. The coefficients of variation in AUC0–24h of lenvatinib on days 1 and 15 were 44.0% and 52.4%, respectively. Although the ABCB1 34...
#1Masaya Sato (UTokyo: University of Tokyo)H-Index: 15
#2Ryosuke Tateishi (UTokyo: University of Tokyo)H-Index: 58
Last. Koji Uchino (UTokyo: University of Tokyo)H-Index: 12
view all 17 authors...
Abstract null Background and Aims null Radiofrequency ablation (RFA) is a widely accepted, minimally invasive treatment for hepatocellular carcinoma (HCC). This study aimed to develop a machine learning (ML) model to predict the risk of HCC recurrence after RFA treatment for individual patients. null Methods null We included a total of 1778 treatment-naive HCC patients who underwent RFA. The cumulative probability of overall recurrence after the initial RFA treatment was 78.9% and 88.0% at 5 and...
#1Hitoshi Maruyama (Juntendo University)H-Index: 24
#2Shuichiro Shiina (Juntendo University)H-Index: 62
#1Hitoshi MaruyamaH-Index: 24
#2Shuichiro ShiinaH-Index: 62
#1Masatoshi KudoH-Index: 119
#2Namiki IzumiH-Index: 73
Last. Shoji KuboH-Index: 59
view all 13 authors...
In the 21st Nationwide Follow-up Survey of Primary Liver Cancer in Japan, data from 22,134 new patients and 41,956 previously followed patients were compiled from 546 institutions over a 2-year period from 1 January 2010 to 31 December 2011. Basic statistics compiled for patients newly registered in the 21st survey were cause of death, past medical history, clinical diagnosis, imaging diagnosis, treatment-related factors, pathological diagnosis, recurrence status, and autopsy findings. Compared ...
#18Norihiro KokudoH-Index: 100
#19Shoji Kubo (OCU: Osaka City University)H-Index: 59
Aim We reviewed the data of a nationwide follow-up survey to determine the impact of hepatitis C virus (HCV) infection on the outcomes of hepatectomy for intrahepatic cholangiocarcinoma (ICC) of the mass-forming (MF) type and combined mass-forming and periductal infiltrating (MF+PI) types. Methods In total, 956 patients with ICC who underwent curative hepatic resection were included in this cohort study, and patients were classified according to virus status. Patients were classified according t...
#1Masatoshi KudoH-Index: 119
#2Yusuke KawamuraH-Index: 41
Last. Tetsuo TakeharaH-Index: 72
view all 25 authors...
#1Tadatoshi Takayama (Nihon University)H-Index: 92
#2Shintaro Yamazaki (Nihon University)H-Index: 17
Last. Osamu Nakashima (Kurume University)H-Index: 50
view all 13 authors...
BACKGROUND Surgical treatment for hepatocellular carcinoma (HCC) is advancing, but a robust prediction model for survival after resection is not available. The aim of this study was to propose a prognostic grading system for resection of HCC. METHODS This was a retrospective, multicentre study of patients who underwent first resection of HCC with curative intent between 2000 and 2007. Patients were divided randomly by a cross-validation method into training and validation sets. Prognostic factor...
#1Michitoshi Goto (Juntendo University)H-Index: 7
#2Kazuhiro Sakamoto (Juntendo University)H-Index: 19
Last. Shuichiro Shiina (Juntendo University)H-Index: 62
view all 12 authors...
We report our experience of an extremely rare case of a simultaneous extrahepatic metastasis of hepatocellular carcinoma (HCC) with long-term relapse-free survival, treated by laparoscopic resection of an abdominal wall tumor and subsequent radiofrequency ablation (RFA) of an intrahepatic lesion. A 76-year-old man visited a local clinic for right lower abdominal pain. He was treated with antibiotics and the symptom resolved. However, a mass was detected in the same region and he was referred to ...
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