Falk Kiefer
Heidelberg University
PsychiatryInternal medicineEndocrinologyPsychologyNeuroscienceNaltrexoneCue reactivityFunctional magnetic resonance imagingAlcohol dependenceAlcohol use disorderCravingAcamprosateAbstinenceAlcoholRelapse preventionAddictionAudiologyAnxietyClinical psychologyMedicinePharmacology
430Publications
60H-index
8,170Citations
Publications 418
Newest
#1Bernd Lenz (FAU: University of Erlangen-Nuremberg)H-Index: 22
#2Christian Weinland (FAU: University of Erlangen-Nuremberg)H-Index: 11
Last. Christiane Mühle (FAU: University of Erlangen-Nuremberg)H-Index: 24
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Alcohol use disorder (AUD) is a severe illness, for which we lack sufficient mechanistic understanding. Preliminary evidence associates AUD with the oxytocin (OXT) system. Here we investigated alterations in endogenous OXT blood concentrations in patients with AUD and their association with alcohol drinking and prospective course. In sex-separated analyses, OXT serum concentrations of 200 in-patients with AUD (56.5% male; baseline, 24-72 h of abstinence) were compared with those of 240 age-match...
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#1Falk Kiefer (Heidelberg University)H-Index: 60
#2Anna E. Goudriaan (UvA: University of Amsterdam)H-Index: 53
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#1Anne Koopmann (Heidelberg University)H-Index: 14
#2Ekaterini Georgiadou (Paracelsus Private Medical University of Salzburg)H-Index: 11
Last. Thomas Hillemacher (Paracelsus Private Medical University of Salzburg)H-Index: 42
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BACKGROUND: Similar to other countries, the government of Germany has implemented various restrictions of social life in March 2020 to slow the spread of COVID-19 pandemic. This results in millions of people being isolated for long periods, which may increase feelings of worry and anxiety. As the consumption of alcohol and tobacco is an often used dysfunctional strategy to cope with such feelings, these restrictions might cause an increase of consumption. Already at the beginning of the COVID-19...
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#1Patrick Bach (Heidelberg University)H-Index: 11
#2Georg Weil (Heidelberg University)H-Index: 3
Last. Wolfgang H. Sommer (Heidelberg University)H-Index: 51
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Pharmacological treatment in alcohol use disorder suffers from modest effect sizes. Efforts have been undertaken to identify patient characteristics that help to select individuals that benefit from pharmacological treatment. Previous studies indicated that neural alcohol cue-reactivity (CR) might provide a marker that identifies patients, which benefit from naltrexone treatment.We investigated the reproducibility of the association between ventral striatum (VS) activation and naltrexone (NTX) t...
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#1Anil BatraH-Index: 26
#2Falk Kiefer (Heidelberg University)H-Index: 60
Last. Kay Uwe PetersenH-Index: 12
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Zusammenfassung. Einleitung: Neben der Pravention des Tabakkonsums bleibt die Herstellung und Sicherung eines hohen Niveaus der Behandlungsqualitat bei schadlichem Gebrauch und Abhangigkeit von Tab...
1 CitationsSource
#1Anil Batra (University of Tübingen)H-Index: 26
#2Falk Kiefer (Heidelberg University)H-Index: 60
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#1Damian Karl (Heidelberg University)H-Index: 3
#2J. Malte Bumb (Heidelberg University)H-Index: 7
Last. Sabine Vollstädt-Klein (Heidelberg University)H-Index: 29
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Rationale Alcohol use disorder is a common and devastating mental illness for which satisfactory treatments are still lacking. Nalmefene, as an opioid receptor modulator, could pharmacologically support the reduction of drinking by reducing the (anticipated) rewarding effects of alcohol and expanding the range of treatment options. It has been hypothesized that nalmefene acts via an indirect modulation of the mesolimbic reward system. So far, only a few imaging findings on the neuronal response ...
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#1Falk Kiefer (Heidelberg University)H-Index: 60
#2Anil BatraH-Index: 26
Last. Sabine HoffmannH-Index: 13
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1 CitationsSource
#2Anne KoopmannH-Index: 14
Last. Falk KieferH-Index: 60
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Background: During the lockdown, governmental restrictions resulted in changes to the day-to-day routines of many individuals. Some people appear to cope with stress by panic buying in an attempt to stockpile specific goods, resulting in empty supermarket shelves. Moreover, e-commerce experienced significant growth during this period. We aimed to investigate potential changes in shopping frequencies and preferred shopping type (offline/online) and their relationship with pandemic-specific anxiet...
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#1Patrick Bach (Heidelberg University)H-Index: 11
#2Martin Grosshans (Heidelberg University)H-Index: 17
Last. Falk Kiefer (Heidelberg University)H-Index: 60
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ABSTRACT Prevalence rates of overweight and obesity are increasing worldwide and are amongst the leading causes of death. Participants with obesity also suffer from poorer mental health with a concomitant reduced quality of life. Bariatric surgery outperforms other existing weight optimization approaches. However, hitherto, it was not possible to identify factors predicting weight loss following surgery. Therefore, we aimed at investigating neural and behavioral predictors of weight loss, as wel...
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