Elisabetta Garibaldi
University of Turin
Internal medicineRadiologyUrologySurgeryOncologyProspective cohort studyMedical physicsCohort studyExternal beam radiotherapyProstateTomotherapyUrinary incontinenceProstate cancerUrinary symptomsToxicityNuclear medicinePost prostatectomyRadiation therapyMedicineUrinary systemImage-guided radiation therapy
99Publications
12H-index
323Citations
Publications 97
Newest
#1Fernando Munoz (AUSL: Academy for Urban School Leadership)H-Index: 11
#2Giuseppe SanguinetiH-Index: 37
Last. A. FaiellaH-Index: 5
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Background: Baseline urinary incontinence (UI) strongly modulates UI recovery after adjuvant/salvage radiotherapy (ART/SRT), inducing clinicians to postpone it “as much as possible”, maximizing UI recovery but possibly reducing efficacy. This series aims to analyze the trend of UI recovery and its predictors at radiotherapy start. Methods: A population of 408 patients treated with ART/SRT enrolled in a cohort study (ClinicalTrials.gov #NCT02803086) aimed at developing predictive models of radiat...
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#1Andrea BresolinH-Index: 1
#2A. FaiellaH-Index: 5
Last. Cesare CozzariniH-Index: 43
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Abstract Background and purpose To assess bowel dose-volume relationships for acute patient-reported intestinal symptoms of patients treated with whole-pelvis intensity-modulated radiotherapy (WPRT) for prostate cancer. Materials and methods Complete data of 415 patients enrolled in a multi institute, prospective trial (#NCT02803086) treated with radical (31%), adjuvant (33%) and salvage (36%) intent at a median dose to pelvic nodes/lymph-nodal area of 53Gy were available. The most severe change...
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#1Xiaodong Zhuang (University of Birmingham)H-Index: 10
#1Xiaodong Zhuang (University of Birmingham)H-Index: 6
Last. Steven P. Lee (University of Birmingham)H-Index: 29
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Engineering T cells to express chimeric antigen receptors (CARs) specific for antigens on hematological cancers has yielded remarkable clinical responses, but with solid tumors, benefit has been more limited. This may reflect lack of suitable target antigens, immune evasion mechanisms in malignant cells, and/or lack of T cell infiltration into tumors. An alternative approach, to circumvent these problems, is targeting the tumor vasculature rather than the malignant cells directly. CLEC14A is a g...
16 CitationsSource
#1Fernando MunozH-Index: 11
#2Giuseppe SanguinetiH-Index: 37
Last. Cesare CozzariniH-Index: 43
view all 20 authors...
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#2Andrea BresolinH-Index: 1
Last. Cesare CozzariniH-Index: 43
view all 20 authors...
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#1Andrea BresolinH-Index: 1
Last. Cesare CozzariniH-Index: 43
view all 20 authors...
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#1Tim Rattay (University of Leicester)H-Index: 9
#2Petra Seibold (DKFZ: German Cancer Research Center)H-Index: 27
Last. Sheryl GreenH-Index: 18
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Background: Acute skin toxicity is a common and usually transient side-effect of breast radiotherapy although, if sufficiently severe, it can affect breast cosmesis, aftercare costs and the patient's quality-of-life. The aim of this study was to develop predictive models for acute skin toxicity using published risk factors and externally validate the models in patients recruited into the prospective multi-center REQUITE (validating pREdictive models and biomarkers of radiotherapy toxicity to red...
1 CitationsSource
#1Igor MonsellatoH-Index: 6
Last. Sara OrecchiaH-Index: 1
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Neoadjuvant chemoradiotherapy followed by surgery is the mainstay treatment for locally advanced rectal cancer, leading to significant decrease in tumor size (downsizing) and a shift towards earlier disease stage (downstaging). Extensive histopathological work-up of the tumor specimen after surgery including tumor regression grading and lymph node status helped to visualize individual tumor sensitivity to chemoradiotherapy, retrospectively. As the response to neoadjuvant chemoradiotherapy is het...
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#1Andrea Bresolin (UniSR: Vita-Salute San Raffaele University)H-Index: 1
Last. Cesare Cozzarini (UniSR: Vita-Salute San Raffaele University)
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Objective. To investigate predictors of patient-reported urinary incontinence (PRUI) in the first 2 years after post-prostatectomy radiotherapy (PORT) with particular emphasis on possible dose-effect relationships. Patients and Methods. Two-hundred-thirteen patients, whose clinical and dosimetric data were prospectively collected within a registered multi-institutional cohort study, underwent PORT with adjuvant (n=106) or salvage (n=107) intent with conventional (n=123, prescribed dose to the pr...
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#1Petra Seibold (DKFZ: German Cancer Research Center)H-Index: 27
#2A Webb (University of Leicester)H-Index: 9
Last. William Li (The Queen's Medical Center)H-Index: 1
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Abstract Purpose REQUITE aimed to establish a resource for multi-national validation of models and biomarkers that predict risk of late toxicity following radiotherapy. The purpose of this article is to provide summary descriptive data. Methods An international, prospective cohort study recruited cancer patients in 26 hospitals in eight countries between April 2014 and March 2017. Target recruitment was 5300 patients. Eligible patients had breast, prostate or lung cancer and planned potentially ...
15 CitationsSource