Jonas Oldgren
Uppsala University
Internal medicineSurgeryCardiologyRandomized controlled trialIntensive care medicineWarfarinAntithromboticAspirinClopidogrelAnticoagulantCoronary artery diseaseDabigatranAtrial fibrillationPercutaneous coronary interventionIn patientAnesthesiaConventional PCIMyocardial infarctionStrokeMedicine
Publications 183
#1David Eccleston (University of Melbourne)H-Index: 13
#2Joseph M. Kim (Brigham and Women's Hospital)
Last. Christopher P. Cannon (Brigham and Women's Hospital)H-Index: 168
view all 14 authors...
Background The RE-DUAL PCI trial demonstrated that in patients with nonvalvular atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI), dual therapy with dabigatran and a P2Y12 inhibitor, either clopidogrel or ticagrelor, reduced the risk of bleeding without an increased risk of thromboembolic events as compared to triple therapy with warfarin in addition to a P2Y12 inhibitor and aspirin. What remains unclear is whether this effect is consistent between males and females un...
#1Alexander P. Benz (Population Health Research Institute)H-Index: 3
#2Ziad Hijazi (Uppsala University)H-Index: 25
Last. Lars Wallentin (Uppsala University)H-Index: 150
view all 8 authors...
Background: The novel ABC (Age, Biomarkers, Clinical History) scores outperform traditional risk scores for stroke, major bleeding and death in patients with atrial fibrillation (AF) receiving oral...
1 CitationsSource
#1Jan SteffelH-Index: 35
#2Ronan Collins (Trinity College, Dublin)H-Index: 22
Last. Mark Field (University of Liverpool)H-Index: 4
view all 29 authors...
1 CitationsSource
#1Benjamin E Peterson (Brigham and Women's Hospital)H-Index: 4
#2Deepak L. Bhatt (Brigham and Women's Hospital)H-Index: 167
Last. InvestigatorsH-Index: 11
view all 16 authors...
Abstract Objectives The aim of this study was to explore the early versus late benefits and risks of dabigatran dual therapy versus warfarin triple therapy in the RE-DUAL PCI (Randomized Evaluation of Dual Antithrombotic Therapy With Dabigatran Versus Triple Therapy With Warfarin in Patients With Nonvalvular Atrial Fibrillation Undergoing Percutaneous Coronary Intervention) trial. Background Patients with atrial fibrillation who undergo percutaneous coronary intervention are at increased risk fo...
#1Giuseppe Gargiulo (University of Naples Federico II)H-Index: 26
#2Christopher P. Cannon (Brigham and Women's Hospital)H-Index: 168
Last. Marco Valgimigli (University of Bern)H-Index: 117
view all 11 authors...
AIMS Safety and efficacy of antithrombotic regimens in patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) may differ based on clinical presentation. We sought to comparing double vs. triple antithrombotic therapy (DAT vs TAT) in AF patients with or without acute coronary syndrome (ACS) undergoing PCI. METHODS AND RESULTS A systematic review and meta-analysis was performed using PubMed to search for non-vitamin K antagonist oral anticoagulant (NOAC)-based r...
4 CitationsSource
#1David Erlinge (Lund University)H-Index: 75
#2Akiko Maehara (NewYork–Presbyterian Hospital)H-Index: 10
Last. Zhipeng ZhouH-Index: 1
view all 140 authors...
Summary Background Near-infrared spectroscopy (NIRS) and intravascular ultrasound are promising imaging modalities to identify non-obstructive plaques likely to cause coronary-related events. We aimed to assess whether combined NIRS and intravascular ultrasound can identify high-risk plaques and patients that are at risk for future major adverse cardiac events (MACEs). Methods PROSPECT II is an investigator-sponsored, multicentre, prospective natural history study done at 14 university hospitals...
4 CitationsSource
#1Jonas Oldgren (Uppsala University)H-Index: 51
#2Sanna M. Laurila (TYKS: Turku University Hospital)H-Index: 1
Last. Pirjo Nuutila (TYKS: Turku University Hospital)H-Index: 87
view all 16 authors...
Aims To explore early effects of dapagliflozin on myocardial function and metabolism in patients with type 2 diabetes without heart failure. Materials and methods Patients with type 2 diabetes on metformin treatment were randomized to double-blind 6-week placebo or dapagliflozin 10 mg daily treatment. Investigations included cardiac function and structure with myocardial resonance imaging (MRI); cardiac oxygen consumption, perfusion and efficiency with [11 C]-acetate positron emission tomography...
#1Larissa Fabritz (University of Birmingham)H-Index: 45
#2Harry J.G.M. Crijns (Maastricht University Medical Centre)H-Index: 83
Last. Paulus Kirchhof (University of Birmingham)H-Index: 108
view all 58 authors...
AIMS The risk of developing atrial fibrillation (AF) and its complications continues to increase, despite good progress in preventing AF-related strokes. METHODS AND RESULTS This article summarizes the outcomes of the 7th Consensus Conference of the Atrial Fibrillation NETwork (AFNET) and the European Heart Rhythm Association (EHRA) held in Lisbon in March 2019. Sixty-five international AF specialists met to present new data and find consensus on pressing issues in AF prevention, management and ...
3 CitationsSource
#1Jonas OldgrenH-Index: 14
#1Jonas OldgrenH-Index: 51
Last. Pirjo NuutilaH-Index: 87
view all 16 authors...
#1Maria Tomasdottir (Uppsala University)H-Index: 1
#2Claes Held (Uppsala University)H-Index: 67
Last. Ziad Hijazi (Uppsala University)H-Index: 25
view all 20 authors...
Abstract Background In patients with coronary heart disease (CHD), atrial fibrillation (AF) is associated with increased morbidity and mortality. We investigated the associations between clinical risk factors and biomarkers with incident AF in patients with CHD. Methods and Results 13,153 patients with optimally treated CHD included in the STABILITY trial with plasma samples obtained at randomization. Mean follow-up time was 3.5 years. The association between clinical risk factors and biomarkers...