Ashley K. Clift
University of Oxford
Internal medicineRadiologySurgeryPathologyOncologyResectionIntensive care medicineAppendixPancreasNeuroendocrine tumorsDiseaseLiver transplantationDebulkingPopulationRadionuclide therapyCoronavirus disease 2019 (COVID-19)Peptide receptorIn patientCancer researchProportional hazards modelRadiation therapyClinical trialMedicineCohortGastroenterology
56Publications
13H-index
405Citations
Publications 58
Newest
#1Tom A. Ranger (University of Oxford)H-Index: 1
#2Judith Burchardt (University of Oxford)
Last. Julia Hippisley-Cox (University of Oxford)H-Index: 70
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Introduction null Hormone replacement therapy (HRT) can help women experiencing menopausal symptoms, but usage has declined due to uncertainty around risks of cancer and some cardiovascular diseases (CVD). Moreover, improved cancer survival rates mean that more women who survive cancer go on to experience menopausal symptoms. Understanding these relationships is important so that women and their clinicians can make informed decisions around the risks and benefits of HRT. This study's primary aim...
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#1Ashley K. Clift (University of Oxford)H-Index: 13
#2Defne Saatci (University of Oxford)H-Index: 1
Last. Covid
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#1Weiqi Liao (University of Oxford)H-Index: 1
#2Ashley K. Clift (University of Oxford)H-Index: 13
Last. Julia Hippisley-Cox (University of Oxford)H-Index: 70
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Background: Pancreatic cancer has the worst survival rate among all cancers. Almost 70% of patients were diagnosed at Stage IV. Aim: This study aimed to investigate the symptoms associated with the diagnoses of pancreatic ductal adenocarcinoma (PDAC) and neuroendocrine neoplasms (PNEN), comparatively characterise the symptomatology between the two tumour types to inform earlier diagnosis. Design and Setting: A nested case-control study was conducted using data from the QResearch database. Patien...
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#1Ashley K. Clift (University of Oxford)H-Index: 13
#2Andrea Frilling (Imperial College London)H-Index: 19
Abstract Surgery represents a fundamental component of treatment strategies in neuroendocrine neoplasms. Resection of the primary tumour as well as loco-regional and distant deposits is currently the only modality possessing chance of cure from neuroendocrine neoplasia disease. However, surgical intervention may also have legitimate palliative intents, such as cytoreduction of hormonally active tumour bulk that is not responsive to medical therapy and/or causes local symptoms. In some scenarios,...
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#1Hajira Dambha-Miller (University of Cambridge)H-Index: 7
#2Pui San Tan (University of Oxford)H-Index: 14
Last. Julia Hippisley-Cox (University of Oxford)H-Index: 70
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Introduction Recent evidence suggests that ethnic minority groups are disproportionately at increased risk of hospitalisation and death from SARS-CoV-2 infection. Population-based evidence on potential explanatory factors across minority groups and within subgroups is lacking. This study aims to quantify the association between ethnicity and the risk of hospitalisation and mortality due to COVID-19. Methods and analysis This is a retrospective cohort study of adults registered across a represent...
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#1Ashley K. Clift (University of Oxford)H-Index: 13
#2Carol Coupland (University of Nottingham)H-Index: 76
Last. Julia Hippisley-Cox (University of Oxford)H-Index: 70
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48 CitationsSource
#1Paul Aveyard (University of Oxford)H-Index: 65
#2Min Gao (PKU: Peking University)H-Index: 4
Last. Julia Hippisley-Cox (University of Oxford)H-Index: 70
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Summary Background Previous studies suggested that the prevalence of chronic respiratory disease in patients hospitalised with COVID-19 was lower than its prevalence in the general population. The aim of this study was to assess whether chronic lung disease or use of inhaled corticosteroids (ICS) affects the risk of contracting severe COVID-19. Methods In this population cohort study, records from 1205 general practices in England that contribute to the QResearch database were linked to Public H...
19 CitationsSource
#1Andrea Frilling (Imperial College London)H-Index: 19
#2Ashley K. Clift (Imperial College London)H-Index: 13
Last. Richard P. BaumH-Index: 63
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Rationale: Neuroendocrine neoplasia (NEN) of small bowel (SBNEN) frequently present with metastatic disease. Theranostics (molecular imaging followed by targeting therapy) allow for personalised medicine. Liquid biopsies enable precise identification of residual disease and real-time monitoring of therapeutic response. Our aim was to determine the clinical utility of a combination of surgery, theranostics, and a multigene blood measurement in metastasised SBNEN. Methods: Inclusion criteria were ...
1 CitationsSource
#1Ashley K. Clift (University of Oxford)H-Index: 13
#2Andrea Frilling (Imperial College London)H-Index: 13
PURPOSE OF REVIEW To comprehensively synthesise and appraise the available evidence regarding therapies for metastatic neuroendocrine neoplasms that exploit the hepatic vasculature to deliver therapy to liver metastases. RECENT FINDINGS Various techniques including transarterial embolisation/chemoembolisation (TAE/TACE) and selective internal radiotherapy (SIRT, also termed radioembolisation [RE]) have been examined in patents with neuroendocrine liver metastases. Variations in the radioactive a...
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