Robin Prestwich
Leeds Teaching Hospitals NHS Trust
CancerInternal medicineRadiologySurgeryOncologyRetrospective cohort studyStage (cooking)Positron emission tomographyHead and neck cancerChemotherapyHead and neck squamous-cell carcinomaCarcinomaChemoradiotherapyOropharyngeal CarcinomaNuclear medicineHead and neckRadiation therapyMedicineOncolytic virusBiologyImmune system
Publications 136
Salivary gland cancers are uncommon neoplasms of the head and neck that exhibit considerable pathological, biological, and clinical diversity, resulting in a paucity of prospective data regarding the use of non-surgical treatments. Chemotherapy has shown limited activity in patients with metastatic disease, and there has been little exploration of its use in definitive management. There is no standard recommendation for the use of systemic therapy, with palliative chemotherapy being considered o...
#1D. Bird (Leeds Teaching Hospitals NHS Trust)H-Index: 4
#2Andrew Scarsbrook (Leeds Teaching Hospitals NHS Trust)H-Index: 29
Last. Robin Prestwich (Leeds Teaching Hospitals NHS Trust)H-Index: 28
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Background This study aimed to quantify the variation in oropharyngeal squamous cell carcinoma gross tumour volume (GTV) delineation between CT, MR and FDG PET-CT imaging.
32 CitationsSource
#1Stephanie R. McKeown (Ulster University)H-Index: 28
#2Paul Hatfield (St James's University Hospital)H-Index: 10
Last. Roger E. Taylor (Swansea University)H-Index: 24
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Most radiotherapy (RT) involves the use of high doses (>50 Gy) to treat malignant disease. However, low to intermediate doses (approximately 3–50 Gy) can provide effective control of a number of benign conditions, ranging from inflammatory/proliferative disorders (e.g. Dupuytren's disease, heterotopic ossification, keloid scarring, pigmented villonodular synovitis) to benign tumours (e.g. glomus tumours or juvenile nasopharyngeal angiofibromas). Current use in UK RT departments is very variable....
43 CitationsSource
#1Robin PrestwichH-Index: 28
#2Sriram VaidyanathanH-Index: 15
Last. Andrew ScarsbrookH-Index: 8
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The identification of robust prognostic and predictive biomarkers would transform the ability to implement an individualised approach to radiotherapy. In this regard, there has been a surge of interest in the use of functional imaging to assess key underlying biological processes within tumours and their response to therapy. Importantly, functional imaging biomarkers hold the potential to evaluate tumour heterogeneity/biology both spatially and temporally. An ever-increasing range of functional ...
10 CitationsSource
#1Ekin ErmişH-Index: 6
#2Mark TeoH-Index: 14
Last. Robin PrestwichH-Index: 28
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Introduction A wide variety of fractionation schedules have been employed for the treatment of early glottic cancer. The aim is to report our 10-year experience of using hypofractionated radiotherapy with 55Gy in 20 fractions at 2.75Gy per fraction.
24 CitationsSource
#1Sumerya Duru BirgiH-Index: 3
#2Mark TeoH-Index: 14
Last. Robin PrestwichH-Index: 28
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Background The aim of this study was to evaluate the disease outcomes of patients treated with definitive and adjuvant radiotherapy for squamous cell carcinomas of the nasal cavity and paranasal sinuses in a single institution.
10 CitationsSource
#1Roger E. Taylor (Swansea University)H-Index: 24
#2P. Hatfield (Leeds Teaching Hospitals NHS Trust)H-Index: 4
Last. R. Shaffer (Royal Surrey County Hospital)H-Index: 3
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Most patients treated by external beam radiotherapy are being treated for cancer. However, historically, many patients have been treated with radiotherapy for a variety of benign (i.e. non-neoplastic) conditions. Furthermore, radiotherapy is also used for the treatment of a wide range of benign tumours [1]. In recent years, the Faculty of Clinical Oncology of the Royal College of Radiologists has become aware that, within the UK, the use of radiotherapy for benign conditions has declined, with v...
8 CitationsSource
#1F. SlevinH-Index: 3
#2Manil SubesingheH-Index: 12
Last. Robin PrestwichH-Index: 28
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Objective:To assess the accuracy of a 4-month post-(chemo)radiotherapy 18-fludeoxyglucose (18F-FDG) positron emission tomography (PET)-CT for head and neck squamous cell carcinoma (HNSCC).Methods:105 patients who underwent a baseline and response assessment 18F-FDG PET-CT scan between 2008 and April 2013 were identified. 18F-FDG PET-CT outcomes were analysed with reference to clinicopathological outcomes.Results:79 of 105 (75%) 18F-FDG PET-CT scans demonstrated a complete metabolic response; 19 ...
29 CitationsSource
#1Louise Murray (University of Leeds)H-Index: 18
#2B. SethugavalarH-Index: 2
Last. Robin PrestwichH-Index: 28
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Abstract Aims Recent radiotherapy guidelines for lymphoma have included involved site radiotherapy (ISRT), involved node radiotherapy (INRT) and irradiation of residual volume after full-course chemotherapy. In the absence of late toxicity data, we aim to compare organ at risk (OAR) dose-metrics and calculated second malignancy risks. Materials and methods Fifteen consecutive patients who had received mediastinal radiotherapy were included. Four radiotherapy plans were generated for each patient...
16 CitationsSource
#1D. BirdH-Index: 4
#2Richard SpeightH-Index: 10
Last. Robin PrestwichH-Index: 28
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