Nicola Alessandro Iacovelli
University of Milan
Quality of lifeCancerInternal medicineRadiologySurgeryPathologyOncologyStage (cooking)Physical therapyHead and neck cancerInduction chemotherapyChemotherapyNasopharyngeal carcinomaPopulationNuclear medicineNasopharyngeal cancerSinonasal cancerLocally advancedIn patientHead and neckNon endemicRadiation therapyMedicine
68Publications
9H-index
247Citations
Publications 67
Newest
#1Marco Bologna (Polytechnic University of Milan)H-Index: 6
#2Valentina D. A. Corino (Polytechnic University of Milan)H-Index: 15
Last. Ester OrlandiH-Index: 23
view all 21 authors...
Advanced stage nasopharyngeal cancer (NPC) shows highly variable treatment outcomes, suggesting the need for independent prognostic factors. This study aims at developing a magnetic resonance imaging (MRI)-based radiomic signature as a prognostic marker for different clinical endpoints in NPC patients from non-endemic areas. A total 136 patients with advanced NPC and available MRI imaging (T1-weighted and T2-weighted) were selected. For each patient, 2144 radiomic features were extracted from th...
1 CitationsSource
Objective: This study aimed to look into the relationship between intensity-modulated-radiotherapy (IMRT)- or volumetric-modulated-arc-therapy (VMAT)-based dose-volume parameters and 5-year outcome for a consecutive series of non-metastatic nasopharyngeal cancer (NPC) patients (pts) treated in a single institution in a non-endemic area in order to identify potential prognostic factors. Materials and methods: A retrospective analysis of consecutive non-metastatic NPC pts treated curatively with I...
2 CitationsSource
#1Rossana IngargiolaH-Index: 2
#2Maria De SantisH-Index: 35
Last. Ester OrlandiH-Index: 23
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This study was an open-label, 2-arms, monocentric, randomized clinical trial comparing Xonrid®, a topical medical device, versus standard of care (SOC) in preventing and treating acute radiation dermatitis (ARD) in Head and Neck Cancer (HNC) and Breast Cancer (BC) patients undergoing radiotherapy (RT). Eligible HNC and BC patients were randomized 1:1 to receive Xonrid® + SOC or SOC during RT. Patients were instructed to apply Xonrid® on the irradiated area three times daily, starting on the firs...
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#1Ester OrlandiH-Index: 23
Last. Piero Nicolai (UNIPD: University of Padua)H-Index: 64
view all 8 authors...
Malignancies of the anterior skull base are rare and recur in 40-80% of treated cases, varying with substantial variance according to histology, stage at primary diagnosis, and other factors. Most recurrences manifest within 2-5 years after primary treatment, but some histologies can relapse even decades after the first presentation. Management of recurrent anterior skull base tumors is challenging and a wide variety of treatment options are available. Similar to the primary setting, surgery is ...
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#1Mauro GuglielmoH-Index: 2
#2Patricia Di PedeH-Index: 2
Last. Paolo Bossi (University of Milan)H-Index: 39
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PURPOSE Fatigue is a distressing symptom in head & neck cancer patients before during and at the end of curative therapy. Pharmacologic and not pharmacologic treatments have been proposed with scarce or no evidence of efficacy. The aim of the study is to evaluate the efficacy of American ginseng in respect to placebo in reducing fatigue in patients treated for head and neck cancer with curative intent. METHODS Thirty-two patients who had completed oncological treatment for a primary Head & neck ...
1 CitationsSource
Jul 1, 2020 in EMBC (International Conference of the IEEE Engineering in Medicine and Biology Society)
#1Marco Bologna (Polytechnic University of Milan)H-Index: 6
#2Valentina D. A. Corino (Polytechnic University of Milan)H-Index: 15
Last. Luca T. Mainardi (Polytechnic University of Milan)H-Index: 35
view all 16 authors...
The purpose of this study was to establish a methodology and technology for the development of an MRI-based radiomic signature for prognosis of overall survival (OS) in nasopharyngeal cancer from non-endemic areas. The signature was trained using 1072 features extracted from the main tumor in T1-weighted and T2-weighted images of 142 patients. A model with 2 radiomic features was obtained (RAD model). Tumor volume and a signature obtained by training the model on permuted survival data (RADperm ...
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#1Ester Orlandi (University of Milan)H-Index: 23
#2Stefano Cavalieri (University of Milan)H-Index: 11
Last. Paolo Bossi (University of Brescia)H-Index: 39
view all 21 authors...
OBJECTIVE: Outcomes of locally advanced epithelial sinonasal cancers remain unsatisfactory; moreover, only limited and heterogeneous data exist on prognostic factors. METHODS: We reviewed all consecutive patients with American Joint Committee Cancer stage III to IV epithelial sinonasal cancers treated with platinum-based induction chemotherapy (IC) followed by locoregional treatment between 1996 and 2015. RESULTS: We identified 69 patients treated with a multimodal approach (IC, surgery, radioth...
6 CitationsSource
#1L. FerellaH-Index: 3
#2Anna CavalloH-Index: 7
Last. Ester OrlandiH-Index: 23
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Background:We evaluated the prognostic role of gross tumor volumes (GTVs) of primary tumor and positive lymph nodes on overall survival (OS) and progression-free survival (PFS) in locally advanced ...
2 CitationsSource
#1Ester OrlandiH-Index: 23
Last. Francesca De Felice (Sapienza University of Rome)H-Index: 21
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Abstract In the last decade, human microbiome research is rapidly growing involving several fields of clinical medicine and population health. Although the microbiome seems to be linked to all sorts of diseases, cancer has the biggest potential to be investigated. Following the publication of the National Institute of Health - Human Microbiome Project (NIH-HMP), the link between Head and Neck Cancer (HNC) and microbiome seems to be a fast-moving field in research area. However, robust evidence-b...
11 CitationsSource
#1Eliana Ivaldi (University of Sassari)H-Index: 2
#2Dalila Di Mario (University of Sassari)H-Index: 1
Last. Ester OrlandiH-Index: 23
view all 10 authors...
Abstract Early stage (T1-2, N0-1) oral squamous cell carcinoma (OSCC) has a generally favorable prognostic outcome. However, locoregional recurrences can occur in up to 30–35% of patients, and 20% will eventually die of disease. National and international treatment guidelines do not recommend the use of postoperative radiotherapy (PORT) in a setting of early OSCC, and highlight surgery alone as the standard single modality treatment. Notwithstanding, the negative prognostic impact of some advers...
4 CitationsSource