Marc G. Besselink
University of Amsterdam
CancerInternal medicineRadiologySurgeryOncologyResectionRetrospective cohort studyRandomized controlled trialIntensive care medicinePancreatitisAcute pancreatitisPancreasMEDLINEPancreatic cancerPercutaneousPancreatic fistulaIn patientGeneral surgeryMedicineGastroenterology
Publications 736
#1Jony van Hilst (UvA: University of Amsterdam)H-Index: 17
#2Nine de Graaf (UvA: University of Amsterdam)H-Index: 1
Last. Marc G. Besselink (UvA: University of Amsterdam)H-Index: 84
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#1Marinus A. Kempeneers (UvA: University of Amsterdam)H-Index: 5
#2Y. Issa (UvA: University of Amsterdam)H-Index: 11
Last. Hjalmar C. van SantvoortH-Index: 55
view all 29 authors...
Objective Pain in chronic pancreatitis is subdivided in a continuous or intermittent pattern, each thought to represent a different entity, requiring specific treatment. Because evidence is missing, we studied pain patterns in a prospective longitudinal nationwide study. Design 1131 patients with chronic pancreatitis (fulfilling M-ANNHEIM criteria) were included between 2011 and 2018 in 30 Dutch hospitals. Patients with continuous or intermittent pain were compared for demographics, pain charact...
3 CitationsSource
#1Esther N. Pijnappel (UvA: University of Amsterdam)H-Index: 1
#2Willemieke P.M. Dijksterhuis (UvA: University of Amsterdam)H-Index: 4
Last. Hanneke W. M. van Laarhoven (UvA: University of Amsterdam)H-Index: 40
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BACKGROUND Metastatic pancreatic ductal adenocarcinoma (PDAC) is characterized by a poor survival rate, which can be improved by systemic treatment. Consensus on the most optimal first- and second-line palliative systemic treatment is lacking. The aim of this study was to describe the use of first- and second-line systemic treatment, overall survival (OS), and time to failure (TTF) of first- and second-line treatment in metastatic PDAC in a real-world setting. PATIENTS AND METHODS Patients with ...
#1Fleur van der Sijde (EUR: Erasmus University Rotterdam)H-Index: 3
#2Zakia Azmani (EUR: Erasmus University Rotterdam)
Last. Quisette P Janssen (EUR: Erasmus University Rotterdam)H-Index: 3
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Background:Biomarkers predicting treatment response may be used to stratify pancreatic ductal adenocarcinoma (PDAC) patients for therapy. The aim of this study was to identify circulating tumor DNA...
#1Emma S. Zwanenburg (UvA: University of Amsterdam)
#2Roel Hompes (UvA: University of Amsterdam)H-Index: 15
Last. Matthijs W N Oomen (UvA: University of Amsterdam)H-Index: 5
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Abstract Introduction: Congenital hyperinsulinism (CHI), or nesidioblastosis, is the most common cause of severe persistent hypoglycemia in neonates. When left untreated, CHI may cause serious brai...
#1Ekaterina PetrovaH-Index: 5
#2J. Annelie Suurmeijer (UvA: University of Amsterdam)
Last. Tobias KeckH-Index: 41
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Abstract null null Background null Evidence on the optimal pancreatic anastomosis during pancreatoduodenectomy is inconclusive. Large multicenter and nationwide registries may provide additional insights. The study compared the practice and outcome of different pancreatic anastomoses during pancreatoduodenectomy, focusing on the rate of postoperative pancreatic fistula, in two large audits of pancreatic surgery. null null null Methods null Posthoc analysis of patients after pancreatoduodenectomy...
#1Nikolaos MachairasH-Index: 2
#2Dimitri A. RaptisH-Index: 32
Last. Charles J. YeoH-Index: 155
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OBJECTIVE The aim of this study was to evaluate whether neoadjuvant therapy (NAT) critically influenced microscopically complete resection (R0) rates and long-term outcomes for patients with pancreatic ductal adenocarcinoma who underwent pancreatoduodenectomy (PD) with portomesenteric vein resection (PVR) from a diverse, world-wide group of high-volume centers. SUMMARY BACKGROUND DATA Limited size studies suggest that NAT improves R0 rates and overall survival compared to upfront surgery in rese...
#1Bobby K Pranger (UMCG: University Medical Center Groningen)H-Index: 2
#2Jacob L. van Dam (EUR: Erasmus University Rotterdam)H-Index: 3
Last. Vincent E de Meijer (UMCG: University Medical Center Groningen)H-Index: 22
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Abstract Background The aim of this study was to determine pancreatic surgery specific short- and long-term complications of pediatric, adolescent and young adult (PAYA) patients who underwent pancreatic resection, as compared to a comparator cohort of adults. Methods A nationwide retrospective cohort study was performed in PAYA patients who underwent pancreatic resection between 2007 and 2016. PAYA was defined as all patients Results A total of 230 patients were included in the PAYA cohort (112...
#1Asbjørn Mohr Drewes (AAU: Aalborg University)H-Index: 78
#2Melena D. Bellin (UMN: University of Minnesota)H-Index: 41
Last. John A. Windsor (University of Auckland)H-Index: 71
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Abstract null null Pain is the most common symptom in chronic pancreatitis (CP) with a major impact on quality of life. Few validated questionnaires to assess pain in CP exist, and the lack of consensus negatively impacts clinical management, research and meta-analysis. This guideline aims to review generic pain questionnaires for their usability in CP, to outline how pain assessment can be modified by confounding factors and pain types, to assess the value of additional measures such as quality...