Usman H. Malabu
James Cook University
Internal medicineEndocrinologySurgeryOdds ratioPediatricsProspective cohort studyAmputationHypothalamusType 2 diabetesDiabetic footDiabetic foot ulcerInsulinDialysisPopulationRisk factorDiabetes mellitusMedicineCohortGastroenterologyNeuropeptide Y receptor
122Publications
17H-index
890Citations
Publications 112
Newest
Background and Aims: Nerve conduction study (NCS) measures how fast an electrical impulse moves through the nerve and is a standard technique for diagnosing and assessing neurological diseases. Despite diabetes and obesity being a common accompaniment of peripheral neuropathy, their effects on NCS patterns have not been elucidated conclusively. Our study aimed to assess several anthropometric and metabolic factors with NCS outcomes to address this gap. Research Design and Methods: This retrospec...
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#1Mimi Wong (UQ: University of Queensland)
#2Usman H. Malabu (JCU: James Cook University)H-Index: 17
Last. YongMong Tan (JCU: James Cook University)H-Index: 1
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Whilst literature is expanding on pasireotide use in the management of Cushing’s disease (CD), there is still currently much unknown about long-term and low-dose pasireotide use in CD. We present a 60-year-old female with residual CD after transphenoidal surgery (TSS), being successfully managed with S.C. pasireotide for over 10 years. For 6 years, her S.C. pasireotide was inadvertently administered at 360 µg twice daily (BID), almost half the recommended dose of 600 µg BID. Despite the low-dose...
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Background: Diabetes mellitus causes a large majority of non-traumatic major and minor amputations globally. Patients with diabetes are clinically complex with a multifactorial association between diabetic foot ulcers (DFU) and subsequent lower extremity amputations (LEA). Few studies show the long-term outcomes within the cohort of DFU-associated LEA. Aim: To highlight the long-term outcomes of LEA as a result of DFU. Methods: PubMed/MEDLINE and Google Scholar were searched for key terms, "diab...
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#1Mary D. Adu (JCU: James Cook University)H-Index: 5
#2Usman H. Malabu (JCU: James Cook University)H-Index: 17
Last. Bunmi S. Malau-Aduli (JCU: James Cook University)H-Index: 13
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Background: Mobile health apps are commonly used to support diabetes self-management. However, there is limited research assessing if such apps are able to meet the basic requirements to retain and engage users. Objective: In this study, we aimed to evaluate participants' retention and engagement with My Care Hub (MCH), a mobile app for diabetes self-management. Methods: This study employed an explanatory mixed-method design. Participants were people with type 1 or type 2 diabetes who used the h...
2 CitationsSource
#1Mary D. Adu (JCU: James Cook University)H-Index: 5
#2Usman H. Malabu (JCU: James Cook University)H-Index: 17
Last. Bunmi S. Malau-Aduli (JCU: James Cook University)H-Index: 13
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The aim of this study was to evaluate the preliminary efficacy and user acceptance of My Care Hub (MCH) mobile app—developed to provide evidenced-based support and education on diabetes self-management (DSM). Using a mixed-methods design, the efficacy and acceptability of MCH were measured among people with type 1 or type 2 diabetes after three weeks of intervention. The primary outcome measure was level of involvement with DSM, while the mediating factors were skills and self-efficacy for DSM. ...
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#1Usman H. Malabu (JCU: James Cook University)H-Index: 17
#2Oyelola A. Adegboye (Australian Institute of Tropical Health and Medicine)H-Index: 10
Last. Kunwarjit S. Sangla (JCU: James Cook University)H-Index: 14
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Aims To evaluate outcomes of diabetic inpatient hypoglycemia among Aboriginal and Torres Strait Islander (ATSI) compared with Australian Caucasian patients.
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#1Mary D. Adu (JCU: James Cook University)H-Index: 5
#2Usman H. Malabu (JCU: James Cook University)H-Index: 17
Last. Bunmi S. Malau-Aduli (JCU: James Cook University)H-Index: 13
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Non-adherence to self-management poses a serious risk to diabetes complications. Digital behavioural change interventions have the potential to provide education and motivate users to regularly engage with self-management of diabetes. This paper describes the development of My Care Hub mobile phone application (app) aimed at supporting self-management in people with type 1 or type 2 diabetes. The development of My Care Hub involved a comprehensive process of healthy behavioural change identifica...
10 CitationsSource
#1Corey S. MoranH-Index: 23
#2Ramesh VeluH-Index: 6
Last. Erik BirosH-Index: 23
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Aneurysms demonstrate vascular smooth muscle cells (VSMC) phenotypic modulation characterized by the prevailing of synthetic over contractile properties. We have shown previously the ability of interferon-gamma (IFN-γ) to switch VSMC from contractile to synthetic phenotype via upregulating the truncated form of tryptophanyl-tRNA synthetase (mini-TrpRS) in vitro. Here we discuss a possible role of the IFN-γ/mini-TrpRS signalling axis in the pathology of human abdominal aortic aneurysm (AAA).
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#1Arnon Gal (UIUC: University of Illinois at Urbana–Champaign)H-Index: 10
#2Stacey E. Burton (Victoria University of Wellington)
Last. Richard K. Burchell (JCU: James Cook University)H-Index: 5
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Abstract Sodium-glucose cotransporter type-2 inhibitors (SGLT2is) reduce glomerular hyperfiltration in diabetic people with early diabetic nephropathy. The objective of this report was to assess changes in glomerular filtration rate in healthy cats after treatment with a SGLT2i. Eight healthy research adult castrated male cats were used in a randomized, controlled, cross-over study design. We induced isolated renal tubular glucosuria by dosing cats with the SGLT2i dapagliflozin. The cats receive...
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#1Erik BirosH-Index: 23
#2Venkat N. VangavetiH-Index: 14
Last. Usman H. MalabuH-Index: 17
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Diabetic foot syndrome demonstrates wound chronicity due to impaired tissue perfusion in lower limbs. Previous studies showed interferon-gamma (IFN-γ), a central inflammatory mediator in diabetic foot syndrome, to induce the truncated form of tryptophanyl-tRNA synthetase (mini-TrpRS) that has strong angiostatic properties. Recently we reported that mini-TrpRS signalling could be blocked in the presence of IFN-γ with D-tryptophan in vitro. Here we discuss the IFN-γ/mini-TrpRS axis in the patholog...
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