Bradley N. Reames
Johns Hopkins University
Internal medicineRadiologySurgeryOncologyLogistic regressionResectionRetrospective cohort studyIntensive care medicinePsychological interventionRegional variationHepatectomyEsophagectomyPancreaticoduodenectomyLocally advanced pancreatic cancerHospital volumePerioperativeMedical educationFamily medicineGeneral surgeryQuality managementMedicine
Publications 40
#1Alex B. Blair (Johns Hopkins University)H-Index: 17
#2Bradley N. Reames (Johns Hopkins University)H-Index: 19
Last. Nita Ahuja (Yale University)H-Index: 63
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BACKGROUND: Margin negative resection offers the best chance of long-term survival in retroperitoneal sarcoma (RPS). En-bloc resection of adjacent structures, including the inferior vena cava (IVC), is often required to achieve negative margins. We review our 20-year experience of en-bloc IVC and RPS resection. METHODS: Retrospective review of patients with RPS resection involving the IVC were matched 1:3 by age and histology to RPS without IVC resection. Prognostic factors for overall survival ...
9 CitationsSource
#1Michele M. Gage (Johns Hopkins University)H-Index: 3
#2Bradley N. Reames (Johns Hopkins University)H-Index: 19
Last. Jin HeH-Index: 40
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Resection with clean margin (R0 resection) is associated with better survival in patients with pancreatic cancer. Over the last decade, advancements in preoperative chemotherapy and radiation therapy in pancreatic cancer have led to expansion of indications for surgical resection. Current guidelines define pancreatic cancer with unreconstructable vascular involvement as locally advanced, or surgically unresectable. We present our experience in managing patients with locally advanced pancreatic c...
3 CitationsSource
#1Bradley N. Reames (Johns Hopkins University)H-Index: 19
#2Michele M. Gage (Johns Hopkins University)H-Index: 3
Last. Jin He (Johns Hopkins University)H-Index: 40
view all 9 authors...
#1Bradley N. Reames (Johns Hopkins University)H-Index: 19
#2Fabio Bagante (University of Verona)H-Index: 27
Last. Timothy M. Pawlik (The Ohio State University Wexner Medical Center)H-Index: 118
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Abstract Background The benefit of adjuvant chemotherapy for resected intrahepatic cholangiocarcinoma (ICC) is unclear. The aim of the current study was to investigate the impact of adjuvant chemotherapy on survival among patients undergoing resection of ICC using a multi-institutional database. Methods 1154 ICC patients undergoing curative-intent hepatectomy between 1990 and 2015 were identified from 14 institutions. Cox proportional hazard modeling was used to determine the impact of adjuvant ...
39 CitationsSource
#1Bradley N. Reames (Johns Hopkins University)H-Index: 19
#2Aslam Ejaz (Johns Hopkins University)H-Index: 34
Last. Timothy M. Pawlik (The Ohio State University Wexner Medical Center)H-Index: 118
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Background Major vascular involvement (IVC or portal vein) for intrahepatic cholangiocarcinoma (ICC) has traditionally been considered a contraindication to resection. We sought to define perioperative outcomes and survival of ICC patients undergoing hepatectomy with major vascular resection in a large international multi-institutional database. Methods A total of 1087 ICC patients who underwent curative-intent hepatectomy between 1990 and 2016 were identified from 13 institutions. Multivariable...
25 CitationsSource
#1Aslam Ejaz (Johns Hopkins University)H-Index: 34
#2Bradley N. Reames (Johns Hopkins University)H-Index: 19
Last. Timothy M. Pawlik (OSU: Ohio State University)H-Index: 118
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Abstract Background Management of neuroendocrine liver metastasis (NELM) in the setting of unresectable disease is poorly defined and the role of debulking remains controversial. The objective of the current study was to define outcomes following non-curative intent liver-directed therapy (debulking) among patients with NELM. Methods 612 patients were identified who underwent liver-directed therapy of NELM from a multi-institutional database. Outcomes were stratified according to curative (R0/R1...
16 CitationsSource
#1Andrea T. Obi (UM: University of Michigan)H-Index: 16
#2Bradley N. Reames (UM: University of Michigan)H-Index: 19
Last. Thomas W. Wakefield (UM: University of Michigan)H-Index: 81
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BackgroundPatients with painful varicose veins and venous insufficiency can be treated by eliminating axial reflux only or by eliminating axial reflux plus phlebectomy with transilluminated powered phlebectomy. This study was undertaken with the aim of determining and improving signs and symptoms of venous disease (measured by venous clinical severity score) and complications (by routine surveillance ultrasound and long-term post-operative follow up) for each treatment strategy.MethodsWe perform...
17 CitationsSource
#1Bradley N. Reames (UM: University of Michigan)H-Index: 19
#2Christopher P. Scally (UM: University of Michigan)H-Index: 11
Last. Hari Nathan (UM: University of Michigan)H-Index: 37
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Abstract Background Management of cystic lesions of the pancreas (CLP) is controversial. In this study, we sought to evaluate national changes in the resection of CLP over time, to better understand the impact of evolving guidelines on CLP management. Methods We used Medicare data to examine CLP resection among patients undergoing pancreatic resection between 2001 and 2012. Patients with a diagnosis of CLP were identified and compared to patients with non-CLP indications. We then examined change...
4 CitationsSource
#1Bradley N. Reames (UM: University of Michigan)H-Index: 19
#2Kyle H. Sheetz (UM: University of Michigan)H-Index: 23
Last. Seth A. Waits (UM: University of Michigan)H-Index: 18
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Objective Although it has been suggested that social-networking services such as Twitter could be used as a tool for medical education, few studies have evaluated its use in this setting. We sought to evaluate the use of Twitter as a novel educational tool in a medical school surgery clerkship. We hypothesized that Twitter can enhance the educational experience of clerkship students. Design We performed a prospective observational study. We created a new Twitter account, and delivered approximat...
25 CitationsSource
#1Mitchell Alameddine (UM: University of Michigan)H-Index: 6
#2Jake Claflin (UM: University of Michigan)H-Index: 5
Last. Sandra L. Wong (UM: University of Michigan)H-Index: 51
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Objective The development of operative skills during general surgery residency depends largely on the resident surgeons’ (residents) ability to accurately self-assess and identify areas for improvement. We compared evaluations of laparoscopic skills and comfort level of residents from both the residents’ and attending surgeons’ (attendings’) perspectives. Design We prospectively observed 111 elective cholecystectomies at the University of Michigan as part of a larger quality improvement initiati...
15 CitationsSource