Cristina Velasquillo
National Autonomous University of Mexico
Self-healing hydrogelsBiomedical engineeringSurgeryPathologyHumanitiesRegeneration (biology)ChemistryExtracellular matrixMaterials scienceGraftingBiocompatibilityChitosanPolycaprolactoneCartilageChondrocyteChemical engineeringTissue engineeringViability assayMedicineBiologyNanocompositeCell biology
45Publications
10H-index
306Citations
Publications 47
Newest
BACKGROUND Few randomized controlled trials with a midterm follow-up have compared matrix-assisted autologous chondrocyte transplantation (MACT) with microfracture (MFx) for knee cartilage lesions. PURPOSE To compare the structural, clinical, and safety outcomes at midterm follow-up of MACT versus MFx for treating symptomatic knee cartilage lesions. STUDY DESIGN Randomized controlled trial; Level of evidence, 1. METHODS A total of 48 patients aged between 18 and 50 years, with 1- to 4-cm2 Intern...
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#1Ximena Vidal-Gutiérrez (UNAM: National Autonomous University of Mexico)H-Index: 1
#2Gina Prado-ProneH-Index: 4
Last. Argelia Almaguer-Flores (UNAM: National Autonomous University of Mexico)H-Index: 11
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Periodontitis is a chronic, multifactorial, inflammatory disease characterized by the progressive destruction of the periodontal tissues. Guided Tissue Regeneration (GTR), involving the use of barrier membranes, is one of the most successful clinical procedures for periodontal therapy. Nevertheless, rapid degradation of the membranes and membrane-related infections are considered two of the major reasons for GTR clinical failure. Recently, integration of non-antibiotic, antimicrobial materials t...
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#2Ilian Haide Serrano-Aguilar (UNAM: National Autonomous University of Mexico)
Last. Cristina VelasquilloH-Index: 10
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Abstract A novel brush-like poly(2-aminoethyl methacrylate) (PAEMA) was grafted onto chitosan (CS) through gamma radiation-induced polymerization. The copolymer (CS-g-PAEMA) was used to prepare a sodium acetate leached poly(urethane-urea) scaffold. The above derivatives were developed, synthesized, and characterized to meet the specific characteristics of biomaterials. The results revealed that this method is an easy and successful route for grafting PAEMA onto CS. The feasibility of preparing a...
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Last. José González-Valdez (Tec: Monterrey Institute of Technology and Higher Education)H-Index: 14
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Abstract This work aims to study the bio-interfacial properties of poly(ester-urethane) composite scaffolds based on poly (3-hydroxybutyrate) [PHB] and modified by surface plasma-radiation-induced graft polymerization of N-isopropylacrylamide (NIPAAm). The delivering power of the Argon radio-frequency plasma was increased from 5−20 W. The yields over the polyurethane surface, grafting density, topographical dimensions, architecture, surface energy, and wettability were surveyed in the establishe...
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#1Eric Ivan Ochoa-Segundo (UNAM: National Autonomous University of Mexico)H-Index: 1
Last. Rogelio Rodríguez-Talavera (UNAM: National Autonomous University of Mexico)H-Index: 2
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Abstract This study aimed at investigating the synthesis, characterization, and search for a biotechnological application proposal for poly [(R)-3-hydroxybutyric acid] (PHB) grafted with the n-hydroxyethyl acrylamide (HEAA) monomer. The novel copolymer was prepared by 60Co gamma radiation-induced-graft polymerization. The effect of different solvents in the graft polymerization; the degree of grafting, crystallinity, and hydrophilicity; the morphology and the thermal properties were evaluated. T...
1 CitationsSource
#2Alberto Ramírez-Mata (BUAP: Benemérita Universidad Autónoma de Puebla)H-Index: 5
Last. Cristina VelasquilloH-Index: 10
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Abstract A poly(ester-urethane) nanocomposite based on 1,6-hexamethylene diisocyanate-trimer, poly(3-hydroxybutyrate), and silica nanoparticles was prepared. The porosity model involved the sodium-acetate in situ particulate leaching technique. Also, the diversity of applications (multifunctionality) of these composite scaffolds is currently unknown. Herein, the scaffold surface topography, cell adhesion, viability, and the use of Azospirillum brasilense to produce biofilms were investigated. Th...
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#1Valentina Alejandra Segovia-Hernández (IPN: Instituto Politécnico Nacional)H-Index: 1
Last. Rosa María Ribas-Aparicio (IPN: Instituto Politécnico Nacional)H-Index: 10
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Abstract The synthesis of the poly(ester-urethanes) using poly(3-hydroxybutyrate) has gained increasing interest as scaffolds for use in tissue engineering despite their moderate hydrophobicity and biocompatibility. However, it is not yet known if the grafting of poly(N‐hydroxyethyl acrylamide) is suitable to improve the degree of hydrophilicity of the surface. This study aims to tailor the surface of these biopolymers by plasma-induced graft polymerization of N‐hydroxyethyl acrylamide. The synt...
3 CitationsSource
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#1Enrique VillalobosH-Index: 3
#2Antonio Madrazo-Ibarra (UP: Panamerican University)H-Index: 1
Last. Clemente IbarraH-Index: 13
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: Objective. To evaluate minimum biosecurity parameters (MBP) for arthroscopic matrix-encapsulated autologous chondrocyte implantation (AMECI) based on patients' clinical outcomes, magnetic resonance imaging (MRI) T2-mapping, Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score, and International Cartilage Repair Society (ICRS) second-look arthroscopic evaluation, laying the basis for a future multicenter study. Design. Pilot clinical study. We analyzed the logistics to perfo...
2 CitationsSource
#1Gina Prado-Prone (UNAM: National Autonomous University of Mexico)H-Index: 4
Last. Argelia Almaguer-Flores (UNAM: National Autonomous University of Mexico)H-Index: 11
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The bacterial colonization of absorbable membranes used for Guided Tissue Regeneration (GTR) as well as their rapid degradation that can cause their rupture, are considered the major reasons of clinical failure. To address this, composite membranes of polycaprolactone (PCL) and gelatin (Gel) loaded with ZnO-NPs (1, 3 and 6 w% relative to PCL content) were fabricated by electrospinning. To fabricate homogeneous fibrillar membranes, acetic acid was used as a sole common solvent to enhance the misc...
6 CitationsSource