Satomi Kasashima
Kanazawa University
RadiologySurgeryPathologyCholine acetyltransferaseImmunohistochemistryAneurysmRetroperitoneal fibrosisEndovascular aneurysm repairAdventitiaAortic aneurysmAortitisAutoimmune pancreatitisAortaAbdominal aortic aneurysmIgG4-related diseaseAbdominal aortaFibrosisMedicineBiologyGastroenterology
58Publications
21H-index
3,626Citations
Publications 58
Newest
#1Kenji NotoharaH-Index: 37
#2Terumi KamisawaH-Index: 60
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 68
view all 29 authors...
The biopsy-based diagnosis of autoimmune pancreatitis (AIP) is difficult but is becoming imperative for pathologists due to the increased amount of endoscopic ultrasound-guided biopsy tissue. To cope with this challenge, we propose guidance for the biopsy diagnosis of type 1 AIP. This guidance is for pathologists and comprises three main parts. The first part includes basic issues on tissue acquisition, staining, and final diagnosis, and is intended for gastroenterologists as well. The second pa...
5 CitationsSource
#1Ryosuke Ota (Kanazawa University)H-Index: 1
#1Ryosuke Ota (Kanazawa University)H-Index: 5
Last. Toshinari Minamoto (Kanazawa University)H-Index: 43
view all 21 authors...
The molecular and clinical characteristics of non-ampullary duodenal adenomas and intramucosal adenocarcinomas are not fully understood because they are rare. To clarify these characteristics, we performed genetic and epigenetic analysis of cancer-related genes in these lesions. One-hundred seven non-ampullary duodenal adenomas and intramucosal adenocarcinomas, including 100 small intestinal type tumors (90 adenomas and 10 intramucosal adenocarcinomas) and 7 gastric type tumors (2 pyloric gland ...
2 CitationsSource
#1Satomi Kasashima (Kanazawa University)H-Index: 21
#2Atsuhiro KawashimaH-Index: 25
Last. Satoru Ozaki (Kanazawa University)H-Index: 19
view all 5 authors...
A 78-year-old male was admitted to our hospital with lumbar pain and was found to have an abdominal aortic aneurysm (AAA) and femoral artery aneurysm (FAA). Initially, the patient underwent endovascular aneurysm repair (EVAR) for the AAA and aneurysmectomy for the FAA. The FAA was diagnosed by histology as immunoglobulin G4-related disease (IgG4-RD). The preoperative serum IgG4 level was within the normal range, although a slight serum interleukin-6 (IL-6) elevation was observed. Four years late...
Source
#1Kenji NotoharaH-Index: 37
#2Terumi KamisawaH-Index: 60
Last. Kazuichi Okazaki (Kansai Medical University)H-Index: 68
view all 16 authors...
Abstract Objectives We examined the efficacy and limitations of acquiring large specimens by endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for diagnosing type 1 autoimmune pancreatitis (AIP). Methods Patients from 12 institutions with non-neoplastic diseases or pancreatic ductal adenocarcinoma (PDAC) with large EUS-FNB specimens were investigated. Slides stained with hematoxylin-eosin, elastic, IgG4, and IgG stains were evaluated. The IgG4-and IgG-positive cell numbers were counted i...
8 CitationsSource
#1Fuminori KasashimaH-Index: 12
#2Satomi KasashimaH-Index: 21
Last. Yoshitaka YamamotoH-Index: 25
view all 5 authors...
Source
#1Satomi Kasashima (Kanazawa University)H-Index: 21
#2Atsuhiro KawashimaH-Index: 25
Last. Hirofumi Takemura (Kanazawa University)H-Index: 16
view all 7 authors...
Abstract Objective Immunoglobulin G4 (IgG4)-related diseases are systemic inflammatory fibrous lesions characterized by elevated serum IgG4 and infiltration of IgG4-positive plasmacytes. They can manifest in vascular lesions as frequently formed aneurysms with prominent thickening of the adventitia (IgG4-related abdominal aortic aneurysm; IgG4-AAA). Matrix metalloproteinases (MMPs) degrade the extracellular matrix, mainly in the tunica media, resulting in destruction of aortic structures to caus...
Source
#1Ichiro Mizushima (Kanazawa University)H-Index: 12
#2Satomi Kasashima (Kanazawa University)H-Index: 21
Last. Nobukazu Ishizaka (Osaka Medical College)H-Index: 34
view all 17 authors...
: IgG4-related disease is a systemic disease, characterized by elevation of serum IgG4 and, histopathologically, massive infiltration of IgG4+ lymphocyte and plasma cell infiltration, storiform fibrosis, causing enlargement, nodules or thickening. It may affect various organs simultaneously or metachronously. Here we analyzed the clinical and pathological characteristics of 99 patients diagnosed with IgG4-related periaortitis/periarteritis and retroperitoneal fibrosis. Of 99 patients (women/men,...
9 CitationsSource
#1Satomi Kasashima (Kanazawa University)H-Index: 21
#2Atsuhiro KawashimaH-Index: 25
Last. Mitsutaka SuzukiH-Index: 1
view all 7 authors...
OBJECTIVE: Immunoglobulin (Ig)G4-related disease is a recently described systemic immune-mediated fibro-inflammatory disease that frequently occurs in tumorous form. Herein, we elucidated the clinicopathological and cytological characteristics of IgG4-related pleural lesions (PLs). PATIENTS AND METHODS: Among 22 patients with fibro-inflammatory PLs of idiopathic aetiology, eight cases were diagnosed as IgG4-PL and the remaining 14 as non-IgG4-PL according to comprehensive diagnostic criteria for...
3 CitationsSource
#1Ichiro Mizushima (Kanazawa University)H-Index: 12
#2Satomi Kasashima (Kanazawa University)H-Index: 21
Last. Nobukazu Ishizaka (Osaka Medical College)H-Index: 34
view all 5 authors...
AbstractPeriaortitis and periarteritis are one of the clinical features of IgG4-related disease. Such vascular manifestations are reported to be present in 10–30% of overall IgG4-related disease, a...
12 CitationsSource
#1Toshiyuki KitaH-Index: 15
#2Tomoyuki ArayaH-Index: 7
Last. Kazuo Kasahara (Kanazawa University)H-Index: 27
view all 7 authors...
Abstract A 65-year-old man was admitted for productive cough and dyspnea. Bilateral pleural effusions were observed on chest X-ray. Although the bilateral pleural effusions were exudative with an increased number of lymphocytes, bacterial culture and polymerase chain reaction analysis for Mycobacterium tuberculosis were negative. Immunological examinations showed high levels of immunoglobulin G4 (IgG4) in both serum and pleural effusion fluid. Pathologic evaluation of a left pleural biopsy speci...
11 CitationsSource